ID   MTXH_METMA              Reviewed;         310 AA.
AC   Q8Q081;
DT   16-JAN-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2002, sequence version 1.
DT   25-MAY-2022, entry version 104.
DE   RecName: Full=Putative methyltransferase mtx subunit H;
DE            EC=2.1.1.-;
GN   Name=mtxH; OrderedLocusNames=MM_0256;
OS   Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM
OS   11833 / OCM 88) (Methanosarcina frisia).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC   Methanosarcinales; Methanosarcinaceae; Methanosarcina.
OX   NCBI_TaxID=192952;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88;
RX   PubMed=12125824;
RA   Deppenmeier U., Johann A., Hartsch T., Merkl R., Schmitz R.A.,
RA   Martinez-Arias R., Henne A., Wiezer A., Baeumer S., Jacobi C.,
RA   Brueggemann H., Lienard T., Christmann A., Boemecke M., Steckel S.,
RA   Bhattacharyya A., Lykidis A., Overbeek R., Klenk H.-P., Gunsalus R.P.,
RA   Fritz H.-J., Gottschalk G.;
RT   "The genome of Methanosarcina mazei: evidence for lateral gene transfer
RT   between Bacteria and Archaea.";
RL   J. Mol. Microbiol. Biotechnol. 4:453-461(2002).
CC   -!- SUBUNIT: May be part of a complex composed of 3 subunits; MtxA, MtxH
CC       and MtxX. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the MtrH family. {ECO:0000305}.
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DR   EMBL; AE008384; AAM29952.1; -; Genomic_DNA.
DR   RefSeq; WP_011032210.1; NC_003901.1.
DR   AlphaFoldDB; Q8Q081; -.
DR   SMR; Q8Q081; -.
DR   STRING; 192952.MM_0256; -.
DR   EnsemblBacteria; AAM29952; AAM29952; MM_0256.
DR   GeneID; 24882382; -.
DR   GeneID; 66135014; -.
DR   KEGG; mma:MM_0256; -.
DR   PATRIC; fig|192952.21.peg.311; -.
DR   eggNOG; arCOG04336; Archaea.
DR   HOGENOM; CLU_048697_0_0_2; -.
DR   OMA; NAPSAWN; -.
DR   Proteomes; UP000000595; Chromosome.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   GO; GO:0006730; P:one-carbon metabolic process; IEA:InterPro.
DR   InterPro; IPR011005; Dihydropteroate_synth-like.
DR   InterPro; IPR023467; MeTrfase_MtrH/MtxH.
DR   InterPro; IPR028342; MtrH.
DR   Pfam; PF02007; MtrH; 1.
DR   PIRSF; PIRSF500206; MtrH; 1.
DR   PIRSF; PIRSF004960; MtrH_MtxH; 1.
DR   SUPFAM; SSF51717; SSF51717; 1.
DR   TIGRFAMs; TIGR01114; mtrH; 1.
PE   3: Inferred from homology;
KW   Methyltransferase; Reference proteome; Transferase.
FT   CHAIN           1..310
FT                   /note="Putative methyltransferase mtx subunit H"
FT                   /id="PRO_0000147571"
SQ   SEQUENCE   310 AA;  33503 MW;  F32281BC369F965D CRC64;
     MFKFQKEQEI ANIAGIKVGG QPGELPTVLA GTIFYNRHEI VEDAAKGLFD RDAAEKLVNL
     QESGSDTTGN PHMVHIFGTT AESITRYIDF IAEVSDSPFL IDSPEGPVRA HAAGYVSEIG
     LADRAVYNSI NMSINTSEMK ALEQSDIDSS IILGFNAKDS SLQGRMEMLE TGAGLLEEGL
     LSIADRCGIV NKLIDPSITP MGNGAGIALR MTIAAKAKWG HPTGSGIHNA PSAWNWLNRQ
     KEKDPVLYKI CDIGSTCLQQ AAAGDFILYG PIEYAEYVFP MAAMSDIMIA EAVADLDIEP
     VERHPINFLV