ID   MTXL_SCHPO              Reviewed;         450 AA.
AC   Q9UUA5;
DT   20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   25-MAY-2022, entry version 115.
DE   RecName: Full=Metaxin-like protein C409.19c;
GN   ORFNames=SPBC409.19c;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX   PubMed=16823372; DOI=10.1038/nbt1222;
RA   Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA   Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA   Yoshida M.;
RT   "ORFeome cloning and global analysis of protein localization in the fission
RT   yeast Schizosaccharomyces pombe.";
RL   Nat. Biotechnol. 24:841-847(2006).
CC   -!- FUNCTION: May be involved in transport of proteins into the
CC       mitochondrion. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus
CC       {ECO:0000269|PubMed:16823372}. Mitochondrion outer membrane
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the metaxin family. {ECO:0000305}.
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DR   EMBL; CU329671; CAB52621.1; -; Genomic_DNA.
DR   PIR; T40446; T40446.
DR   RefSeq; NP_595469.1; NM_001021379.2.
DR   AlphaFoldDB; Q9UUA5; -.
DR   SMR; Q9UUA5; -.
DR   BioGRID; 277474; 7.
DR   STRING; 4896.SPBC409.19c.1; -.
DR   MaxQB; Q9UUA5; -.
DR   PaxDb; Q9UUA5; -.
DR   EnsemblFungi; SPBC409.19c.1; SPBC409.19c.1:pep; SPBC409.19c.
DR   PomBase; SPBC409.19c; -.
DR   VEuPathDB; FungiDB:SPBC409.19c; -.
DR   eggNOG; KOG3028; Eukaryota.
DR   HOGENOM; CLU_608540_0_0_1; -.
DR   InParanoid; Q9UUA5; -.
DR   OMA; AQAFRIR; -.
DR   PhylomeDB; Q9UUA5; -.
DR   PRO; PR:Q9UUA5; -.
DR   Proteomes; UP000002485; Chromosome II.
DR   GO; GO:0005737; C:cytoplasm; HDA:PomBase.
DR   GO; GO:0005829; C:cytosol; HDA:PomBase.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0001401; C:SAM complex; ISS:PomBase.
DR   GO; GO:0007005; P:mitochondrion organization; IBA:GO_Central.
DR   GO; GO:0007008; P:outer mitochondrial membrane organization; ISS:PomBase.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   InterPro; IPR036282; Glutathione-S-Trfase_C_sf.
DR   InterPro; IPR033468; Metaxin_GST.
DR   InterPro; IPR019564; Sam37/metaxin_N.
DR   Pfam; PF17171; GST_C_6; 1.
DR   Pfam; PF10568; Tom37; 1.
DR   SUPFAM; SSF47616; SSF47616; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Membrane; Mitochondrion; Mitochondrion outer membrane; Nucleus;
KW   Protein transport; Reference proteome; Transport.
FT   CHAIN           1..450
FT                   /note="Metaxin-like protein C409.19c"
FT                   /id="PRO_0000358933"
FT   REGION          355..407
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          423..450
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        359..401
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   450 AA;  51183 MW;  152D949888522887 CRC64;
     MLQLFIYSPG LGQPTMDPGC LAALIYCALA VPKDEIEILR TANSGMSPTH KLPALWDGHV
     WIGSLKNILI YLKQKGYNLD NFDAKQLANV MAFTSLLEGS VNDLWLLEAF VNEENFVEAI
     RPAWSKALKF PHNYLTPNAL QRQAKERLAQ TLGIRDEEVS YEASRMPISH KWTNATRHRQ
     ALLRTQARRI RISSLARQVY GSLESLISDS KFIFGEKPTS LDCLFYAYLS FHAFTNELPQ
     ATLRPCLQFN SPKLYAYLKS LRETWFSDDS NILSPLSIKV QPENLLTIAR LAWNNVTAKA
     NDTRKSITKF SVPPERKLLW ARNGFFIFAS AFSFVWFVIS NGIVVIETED DEASFEEVDD
     AKESIQEKEI DETTESKATH DSSETSSSKE LPKEEEKESS SFDLQPLSAQ DLLFSGFAED
     EIMDEEFGYD DDDDEEFDLD DLDDLEEEIV