MT_PERVI
ID MT_PERVI Reviewed; 73 AA.
AC Q9U568; O96388; Q9U569;
DT 26-SEP-2001, integrated into UniProtKB/Swiss-Prot.
DT 26-SEP-2001, sequence version 2.
DT 03-AUG-2022, entry version 60.
DE RecName: Full=Metallothionein;
DE Short=MT;
GN Name=MT1;
GN and
GN Name=MT2;
OS Perna viridis (Asian green mussel) (Mytilus viridis).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC Autobranchia; Pteriomorphia; Mytilida; Mytiloidea; Mytilidae; Mytilinae;
OC Perna.
OX NCBI_TaxID=73031;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA].
RX PubMed=10451422;
RX DOI=10.1002/(sici)1097-010x(19990901)284:4<445::aid-jez11>3.0.co;2-t;
RA Khoo H.W., Patel K.H.;
RT "Metallothionein cDNA, promoter, and genomic sequences of the tropical
RT green mussel, Perna viridis.";
RL J. Exp. Zool. 284:445-453(1999).
CC -!- FUNCTION: The metallothioneins are involved in the cellular
CC sequestration of toxic metal ions.
CC -!- SIMILARITY: Belongs to the metallothionein superfamily. Type 2 family.
CC {ECO:0000305}.
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DR EMBL; AF092971; AAF22486.1; -; Genomic_DNA.
DR EMBL; AF092972; AAF22487.1; -; Genomic_DNA.
DR EMBL; AF036904; AAD02054.1; -; mRNA.
DR AlphaFoldDB; Q9U568; -.
DR SMR; Q9U568; -.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR InterPro; IPR001008; Metalthion_mollusc.
DR PRINTS; PR00875; MTMOLLUSC.
PE 3: Inferred from homology;
KW Cadmium; Metal-binding; Metal-thiolate cluster.
FT CHAIN 1..73
FT /note="Metallothionein"
FT /id="PRO_0000197334"
FT BINDING 15
FT /ligand="Cd(2+)"
FT /ligand_id="ChEBI:CHEBI:48775"
FT /ligand_label="1"
FT /evidence="ECO:0000250|UniProtKB:P33187"
FT BINDING 19
FT /ligand="Cd(2+)"
FT /ligand_id="ChEBI:CHEBI:48775"
FT /ligand_label="1"
FT /evidence="ECO:0000250|UniProtKB:P33187"
FT BINDING 19
FT /ligand="Cd(2+)"
FT /ligand_id="ChEBI:CHEBI:48775"
FT /ligand_label="2"
FT /evidence="ECO:0000250|UniProtKB:P33187"
FT BINDING 24
FT /ligand="Cd(2+)"
FT /ligand_id="ChEBI:CHEBI:48775"
FT /ligand_label="2"
FT /evidence="ECO:0000250|UniProtKB:P33187"
FT BINDING 26
FT /ligand="Cd(2+)"
FT /ligand_id="ChEBI:CHEBI:48775"
FT /ligand_label="3"
FT /evidence="ECO:0000250|UniProtKB:P33187"
FT BINDING 30
FT /ligand="Cd(2+)"
FT /ligand_id="ChEBI:CHEBI:48775"
FT /ligand_label="3"
FT /evidence="ECO:0000250|UniProtKB:P33187"
FT BINDING 32
FT /ligand="Cd(2+)"
FT /ligand_id="ChEBI:CHEBI:48775"
FT /ligand_label="1"
FT /evidence="ECO:0000250|UniProtKB:P33187"
FT BINDING 32
FT /ligand="Cd(2+)"
FT /ligand_id="ChEBI:CHEBI:48775"
FT /ligand_label="3"
FT /evidence="ECO:0000250|UniProtKB:P33187"
FT BINDING 36
FT /ligand="Cd(2+)"
FT /ligand_id="ChEBI:CHEBI:48775"
FT /ligand_label="1"
FT /evidence="ECO:0000250|UniProtKB:P33187"
FT BINDING 38
FT /ligand="Cd(2+)"
FT /ligand_id="ChEBI:CHEBI:48775"
FT /ligand_label="2"
FT /evidence="ECO:0000250|UniProtKB:P33187"
FT BINDING 41
FT /ligand="Cd(2+)"
FT /ligand_id="ChEBI:CHEBI:48775"
FT /ligand_label="2"
FT /evidence="ECO:0000250|UniProtKB:P33187"
FT BINDING 41
FT /ligand="Cd(2+)"
FT /ligand_id="ChEBI:CHEBI:48775"
FT /ligand_label="3"
FT /evidence="ECO:0000250|UniProtKB:P33187"
FT BINDING 45
FT /ligand="Cd(2+)"
FT /ligand_id="ChEBI:CHEBI:48775"
FT /ligand_label="4"
FT /evidence="ECO:0000250|UniProtKB:P33187"
FT BINDING 47
FT /ligand="Cd(2+)"
FT /ligand_id="ChEBI:CHEBI:48775"
FT /ligand_label="5"
FT /evidence="ECO:0000250|UniProtKB:P33187"
FT BINDING 52
FT /ligand="Cd(2+)"
FT /ligand_id="ChEBI:CHEBI:48775"
FT /ligand_label="5"
FT /evidence="ECO:0000250|UniProtKB:P33187"
FT BINDING 54
FT /ligand="Cd(2+)"
FT /ligand_id="ChEBI:CHEBI:48775"
FT /ligand_label="5"
FT /evidence="ECO:0000250|UniProtKB:P33187"
FT BINDING 54
FT /ligand="Cd(2+)"
FT /ligand_id="ChEBI:CHEBI:48775"
FT /ligand_label="6"
FT /evidence="ECO:0000250|UniProtKB:P33187"
FT BINDING 58
FT /ligand="Cd(2+)"
FT /ligand_id="ChEBI:CHEBI:48775"
FT /ligand_label="4"
FT /evidence="ECO:0000250|UniProtKB:P33187"
FT BINDING 58
FT /ligand="Cd(2+)"
FT /ligand_id="ChEBI:CHEBI:48775"
FT /ligand_label="5"
FT /evidence="ECO:0000250|UniProtKB:P33187"
FT BINDING 64
FT /ligand="Cd(2+)"
FT /ligand_id="ChEBI:CHEBI:48775"
FT /ligand_label="4"
FT /evidence="ECO:0000250|UniProtKB:P33187"
FT BINDING 66
FT /ligand="Cd(2+)"
FT /ligand_id="ChEBI:CHEBI:48775"
FT /ligand_label="6"
FT /evidence="ECO:0000250|UniProtKB:P33187"
FT BINDING 70
FT /ligand="Cd(2+)"
FT /ligand_id="ChEBI:CHEBI:48775"
FT /ligand_label="6"
FT /evidence="ECO:0000250|UniProtKB:P33187"
FT BINDING 72
FT /ligand="Cd(2+)"
FT /ligand_id="ChEBI:CHEBI:48775"
FT /ligand_label="4"
FT /evidence="ECO:0000250|UniProtKB:P33187"
FT BINDING 72
FT /ligand="Cd(2+)"
FT /ligand_id="ChEBI:CHEBI:48775"
FT /ligand_label="6"
FT /evidence="ECO:0000250|UniProtKB:P33187"
FT CONFLICT 38
FT /note="C -> CGC (in Ref. 1; AAD02054)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 73 AA; 7254 MW; 42293A9547DF5CA8 CRC64;
MPSPCNCIET QVCICGTGCS GEGCRCGDAC KCSSGCGCSG CKVVCKCQPG ECACGKQCTG
PDTCKCDSSC SCK
