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MU118_SCHPO
ID   MU118_SCHPO             Reviewed;         141 AA.
AC   O94328;
DT   20-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT   22-SEP-2009, sequence version 2.
DT   03-AUG-2022, entry version 90.
DE   RecName: Full=Meiotically up-regulated gene 118 protein;
GN   Name=mug118; ORFNames=SPBC725.12;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   FUNCTION IN MEIOSIS.
RX   PubMed=16303567; DOI=10.1016/j.cub.2005.10.038;
RA   Martin-Castellanos C., Blanco M., Rozalen A.E., Perez-Hidalgo L.,
RA   Garcia A.I., Conde F., Mata J., Ellermeier C., Davis L., San-Segundo P.,
RA   Smith G.R., Moreno S.;
RT   "A large-scale screen in S. pombe identifies seven novel genes required for
RT   critical meiotic events.";
RL   Curr. Biol. 15:2056-2062(2005).
RN   [3]
RP   SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX   PubMed=16823372; DOI=10.1038/nbt1222;
RA   Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA   Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA   Yoshida M.;
RT   "ORFeome cloning and global analysis of protein localization in the fission
RT   yeast Schizosaccharomyces pombe.";
RL   Nat. Biotechnol. 24:841-847(2006).
CC   -!- FUNCTION: Has a role in meiosis. {ECO:0000269|PubMed:16303567}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:16823372}.
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DR   EMBL; CU329671; CAA22184.2; -; Genomic_DNA.
DR   PIR; T40664; T40664.
DR   RefSeq; NP_595492.2; NM_001021403.2.
DR   AlphaFoldDB; O94328; -.
DR   SMR; O94328; -.
DR   BioGRID; 277687; 1.
DR   DIP; DIP-59224N; -.
DR   IntAct; O94328; 1.
DR   STRING; 4896.SPBC725.12.1; -.
DR   MaxQB; O94328; -.
DR   PaxDb; O94328; -.
DR   PRIDE; O94328; -.
DR   EnsemblFungi; SPBC725.12.1; SPBC725.12.1:pep; SPBC725.12.
DR   GeneID; 2541173; -.
DR   KEGG; spo:SPBC725.12; -.
DR   PomBase; SPBC725.12; -.
DR   VEuPathDB; FungiDB:SPBC725.12; -.
DR   HOGENOM; CLU_1856457_0_0_1; -.
DR   OMA; ASTIRMR; -.
DR   PRO; PR:O94328; -.
DR   Proteomes; UP000002485; Chromosome II.
DR   GO; GO:0032133; C:chromosome passenger complex; IDA:PomBase.
DR   GO; GO:0000775; C:chromosome, centromeric region; IBA:GO_Central.
DR   GO; GO:0000776; C:kinetochore; IDA:PomBase.
DR   GO; GO:0072686; C:mitotic spindle; IDA:PomBase.
DR   GO; GO:1990023; C:mitotic spindle midzone; IDA:PomBase.
DR   GO; GO:0005730; C:nucleolus; IDA:PomBase.
DR   GO; GO:0005634; C:nucleus; HDA:PomBase.
DR   GO; GO:0051233; C:spindle midzone; IBA:GO_Central.
DR   GO; GO:0051321; P:meiotic cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0000070; P:mitotic sister chromatid segregation; IMP:PomBase.
DR   InterPro; IPR018851; Borealin_N.
DR   Pfam; PF10444; Nbl1_Borealin_N; 1.
PE   1: Evidence at protein level;
KW   Meiosis; Nucleus; Reference proteome.
FT   CHAIN           1..141
FT                   /note="Meiotically up-regulated gene 118 protein"
FT                   /id="PRO_0000278506"
FT   REGION          106..141
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   141 AA;  16181 MW;  CF82BD195CFD6101 CRC64;
     MMNKRKRVEE LGETKHRQVR QRILQEHKND ILENLAFELS DKVRRLRSNA SLLASTIRMR
     GEMRIAAIPR AQRNMHLRDL KNHLSCNVSA TPWRTKIKEF YNLDELSSQK SARQPTKTVA
     SSSSSSSKST TVSKSSSKSQ V
 
 
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