ID   MU133_SCHPO             Reviewed;         513 AA.
AC   Q10240;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   25-MAY-2022, entry version 92.
DE   RecName: Full=Meiotically up-regulated gene 133 protein;
GN   Name=mug133; ORFNames=SPAC4G9.07;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   FUNCTION IN MEIOSIS.
RX   PubMed=16303567; DOI=10.1016/j.cub.2005.10.038;
RA   Martin-Castellanos C., Blanco M., Rozalen A.E., Perez-Hidalgo L.,
RA   Garcia A.I., Conde F., Mata J., Ellermeier C., Davis L., San-Segundo P.,
RA   Smith G.R., Moreno S.;
RT   "A large-scale screen in S. pombe identifies seven novel genes required for
RT   critical meiotic events.";
RL   Curr. Biol. 15:2056-2062(2005).
RN   [3]
RP   SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX   PubMed=16823372; DOI=10.1038/nbt1222;
RA   Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA   Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA   Yoshida M.;
RT   "ORFeome cloning and global analysis of protein localization in the fission
RT   yeast Schizosaccharomyces pombe.";
RL   Nat. Biotechnol. 24:841-847(2006).
CC   -!- FUNCTION: Has a role in meiosis. {ECO:0000269|PubMed:16303567}.
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus {ECO:0000269|PubMed:16823372}.
CC       Vacuole membrane {ECO:0000269|PubMed:16823372}.
CC   -!- SIMILARITY: Belongs to the UPF0300 family. {ECO:0000305}.
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DR   EMBL; CU329670; CAA93557.1; -; Genomic_DNA.
DR   PIR; T38866; T38866.
DR   RefSeq; NP_593689.1; NM_001019121.2.
DR   AlphaFoldDB; Q10240; -.
DR   STRING; 4896.SPAC4G9.07.1; -.
DR   PaxDb; Q10240; -.
DR   EnsemblFungi; SPAC4G9.07.1; SPAC4G9.07.1:pep; SPAC4G9.07.
DR   GeneID; 2543433; -.
DR   KEGG; spo:SPAC4G9.07; -.
DR   PomBase; SPAC4G9.07; mug133.
DR   VEuPathDB; FungiDB:SPAC4G9.07; -.
DR   HOGENOM; CLU_038731_0_0_1; -.
DR   OMA; ILLESCY; -.
DR   PhylomeDB; Q10240; -.
DR   PRO; PR:Q10240; -.
DR   Proteomes; UP000002485; Chromosome I.
DR   GO; GO:0000329; C:fungal-type vacuole membrane; HDA:PomBase.
DR   GO; GO:0005794; C:Golgi apparatus; HDA:PomBase.
DR   GO; GO:0051321; P:meiotic cell cycle; IEA:UniProtKB-KW.
DR   InterPro; IPR013903; Meiotic_expression.
DR   Pfam; PF08594; UPF0300; 1.
PE   1: Evidence at protein level;
KW   Golgi apparatus; Meiosis; Membrane; Reference proteome; Vacuole.
FT   CHAIN           1..513
FT                   /note="Meiotically up-regulated gene 133 protein"
FT                   /id="PRO_0000118857"
SQ   SEQUENCE   513 AA;  60362 MW;  3025AE8E81A89402 CRC64;
     MEECKLDINK GKDAEILYEE YKYHEIKEMS FSSCARTSPE LLKKFGCDAH VITSVEGAPK
     KENKKIWEFF KGSNKIKNLF TMFTCCFAND EEEIWGEETN ESVVYKEYTY NSRWKIEIPS
     YPVREIPYVV ADTPYNKLLC PLSSLEWVSK LILMDNANSI GMKNNRYSTN PFIYGMCYII
     RNNANRILLE SCYCENSTGM STCPRILEFM PYEPLLKYNS YRLLSTYENS YKELSEMLTN
     NNAPLEVLIH HVMLYHYYPS FLQSALWTAV SSYLEERCNN GLYSKLLVKA AKQHFGDIRL
     YFVTPDDIYT FDHCNNWIAI VTRNFMAYIE TKRKLEFDSI PFNCPLITQL FPLISSPKEM
     AWLLLIVCTD SNESWFPVHA YINTKTRILR PRSPKLDFFL KESDLLYFQD KQSISEFDII
     RKDLLEDLIQ CDSYVNTREQ LRRRRETLNR KRITIAKLQN NHSQITFPYK RHNIHKSVDS
     IQFCKPASNL LTLKDNSYTQ IPLEPLLLAE ISV