ID   MU134_SCHPO             Reviewed;         432 AA.
AC   O42654;
DT   29-MAR-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-1998, sequence version 1.
DT   25-MAY-2022, entry version 87.
DE   RecName: Full=Meiotically up-regulated gene 134 protein;
GN   Name=mug134; ORFNames=SPAC10F6.15;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   FUNCTION IN MEIOSIS.
RX   PubMed=16303567; DOI=10.1016/j.cub.2005.10.038;
RA   Martin-Castellanos C., Blanco M., Rozalen A.E., Perez-Hidalgo L.,
RA   Garcia A.I., Conde F., Mata J., Ellermeier C., Davis L., San-Segundo P.,
RA   Smith G.R., Moreno S.;
RT   "A large-scale screen in S. pombe identifies seven novel genes required for
RT   critical meiotic events.";
RL   Curr. Biol. 15:2056-2062(2005).
RN   [3]
RP   SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX   PubMed=16823372; DOI=10.1038/nbt1222;
RA   Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA   Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA   Yoshida M.;
RT   "ORFeome cloning and global analysis of protein localization in the fission
RT   yeast Schizosaccharomyces pombe.";
RL   Nat. Biotechnol. 24:841-847(2006).
CC   -!- FUNCTION: Has a role in meiosis. {ECO:0000269|PubMed:16303567}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cell cortex
CC       {ECO:0000269|PubMed:16823372}.
CC   -!- SIMILARITY: Belongs to the UPF0300 family. {ECO:0000305}.
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DR   EMBL; CU329670; CAA15728.1; -; Genomic_DNA.
DR   PIR; T37509; T37509.
DR   RefSeq; NP_593266.1; NM_001018663.2.
DR   AlphaFoldDB; O42654; -.
DR   BioGRID; 279487; 5.
DR   PaxDb; O42654; -.
DR   EnsemblFungi; SPAC10F6.15.1; SPAC10F6.15.1:pep; SPAC10F6.15.
DR   GeneID; 2543053; -.
DR   KEGG; spo:SPAC10F6.15; -.
DR   PomBase; SPAC10F6.15; -.
DR   VEuPathDB; FungiDB:SPAC10F6.15; -.
DR   HOGENOM; CLU_639613_0_0_1; -.
DR   OMA; EYLRAGP; -.
DR   PhylomeDB; O42654; -.
DR   PRO; PR:O42654; -.
DR   Proteomes; UP000002485; Chromosome I.
DR   GO; GO:0005938; C:cell cortex; HDA:PomBase.
DR   GO; GO:0051321; P:meiotic cell cycle; IEA:UniProtKB-KW.
DR   InterPro; IPR013903; Meiotic_expression.
DR   Pfam; PF08594; UPF0300; 1.
PE   1: Evidence at protein level;
KW   Cytoplasm; Meiosis; Reference proteome.
FT   CHAIN           1..432
FT                   /note="Meiotically up-regulated gene 134 protein"
FT                   /id="PRO_0000118859"
SQ   SEQUENCE   432 AA;  49448 MW;  C6CAEB860CCFDE9F CRC64;
     MNYNANVVKF HSTILHKFAL KISKFLILCM RRNKRQLACM KCQCENPMAA ITYADIEYPH
     NTHFLLLDSI SWIPCTCKIL KLKEFELPDR FDIPNLFYDG WLSYVFHTFS GVYLKIGYEM
     DESGFCLPDQ VYHLIDNHSC IQTAVSHLLR NHQALFKYLC DYLRSGEFPL TVLIHHVMLY
     QYYPKSLQEA LWAAVEHYVN NSGEAYSTVQ KLAVQKKIGN IRMYLVNPRD IFALGSTCNC
     IVVSSSNFQS YVQLRKPLLE NNLPYEIDGF DKILQCANSE ADIGWIAMIH CIGSNGYAFP
     IHLYLNMKKN IFLGKLPEST LLLYNSDGAI FKNPPSSKKE CDFYNQLLLD LCKCRQFNAE
     MECNMKKLFN NPTGLHSLPN LPNFSEAGSA KSSNFCSSKD NCLTNRLTLN CLDTPSDENG
     EDIAIQLIIP AE