ID   MU136_SCHPO             Reviewed;         372 AA.
AC   O43061;
DT   20-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-1998, sequence version 1.
DT   25-MAY-2022, entry version 103.
DE   RecName: Full=Meiotically up-regulated gene 136 protein;
DE   Flags: Precursor;
GN   Name=mug136; ORFNames=SPBC4C3.08;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   FUNCTION IN MEIOSIS.
RX   PubMed=16303567; DOI=10.1016/j.cub.2005.10.038;
RA   Martin-Castellanos C., Blanco M., Rozalen A.E., Perez-Hidalgo L.,
RA   Garcia A.I., Conde F., Mata J., Ellermeier C., Davis L., San-Segundo P.,
RA   Smith G.R., Moreno S.;
RT   "A large-scale screen in S. pombe identifies seven novel genes required for
RT   critical meiotic events.";
RL   Curr. Biol. 15:2056-2062(2005).
RN   [3]
RP   SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX   PubMed=16823372; DOI=10.1038/nbt1222;
RA   Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA   Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA   Yoshida M.;
RT   "ORFeome cloning and global analysis of protein localization in the fission
RT   yeast Schizosaccharomyces pombe.";
RL   Nat. Biotechnol. 24:841-847(2006).
CC   -!- FUNCTION: Has a role in meiosis. {ECO:0000269|PubMed:16303567}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:16823372}.
CC       Endoplasmic reticulum {ECO:0000269|PubMed:16823372}. Golgi apparatus
CC       {ECO:0000269|PubMed:16823372}.
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DR   EMBL; CU329671; CAA16830.1; -; Genomic_DNA.
DR   PIR; T40489; T40489.
DR   RefSeq; NP_596297.1; NM_001022218.2.
DR   AlphaFoldDB; O43061; -.
DR   SMR; O43061; -.
DR   BioGRID; 277521; 11.
DR   STRING; 4896.SPBC4C3.08.1; -.
DR   CAZy; GT8; Glycosyltransferase Family 8.
DR   PaxDb; O43061; -.
DR   PRIDE; O43061; -.
DR   EnsemblFungi; SPBC4C3.08.1; SPBC4C3.08.1:pep; SPBC4C3.08.
DR   GeneID; 2541006; -.
DR   KEGG; spo:SPBC4C3.08; -.
DR   PomBase; SPBC4C3.08; mug136.
DR   VEuPathDB; FungiDB:SPBC4C3.08; -.
DR   eggNOG; KOG1950; Eukaryota.
DR   HOGENOM; CLU_048469_1_1_1; -.
DR   InParanoid; O43061; -.
DR   OMA; WKDQFTK; -.
DR   PhylomeDB; O43061; -.
DR   Reactome; R-SPO-6798695; Neutrophil degranulation.
DR   Reactome; R-SPO-70221; Glycogen breakdown (glycogenolysis).
DR   PRO; PR:O43061; -.
DR   Proteomes; UP000002485; Chromosome II.
DR   GO; GO:0005737; C:cytoplasm; HDA:PomBase.
DR   GO; GO:0005783; C:endoplasmic reticulum; HDA:PomBase.
DR   GO; GO:0005794; C:Golgi apparatus; IDA:PomBase.
DR   GO; GO:0001962; F:alpha-1,3-galactosyltransferase activity; IDA:PomBase.
DR   GO; GO:0016757; F:glycosyltransferase activity; IBA:GO_Central.
DR   GO; GO:0051321; P:meiotic cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0006487; P:protein N-linked glycosylation; IGI:PomBase.
DR   GO; GO:0006493; P:protein O-linked glycosylation; EXP:PomBase.
DR   Gene3D; 3.90.550.10; -; 1.
DR   InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR   SUPFAM; SSF53448; SSF53448; 1.
PE   1: Evidence at protein level;
KW   Cytoplasm; Endoplasmic reticulum; Golgi apparatus; Meiosis;
KW   Reference proteome; Signal.
FT   SIGNAL          1..34
FT                   /evidence="ECO:0000255"
FT   CHAIN           35..372
FT                   /note="Meiotically up-regulated gene 136 protein"
FT                   /id="PRO_0000278627"
SQ   SEQUENCE   372 AA;  43789 MW;  332D751B8CF49611 CRC64;
     MRLYFSAFRH PKRLGLCLLI TLSIILLGWQ CVLLYNHSPE IQRSVYTLTG LAPSSKMAFV
     TMLTVRAANG ENEVENTQQD WYYNSTRLLV HRLVKFKPTK SKYPVVVLAM KGIDQWKLDQ
     LQEDGAIVKV VDPLYAHEVV DDVNDIALLD SRWSMMFTKL RVFEMYEYDR ICFLDSDILP
     IKKMDKVFDV HQLSYSKDSV LFPPTLFYKP RRSIFWRRFT EEFAAYGLTR DDLYPYVFAA
     VSDPGMWHET PPPFKDYFNA GLFVFKPLKA HYKRLMALAR FPKLYDNANM MEQSLLNFAY
     NSAGAFPWES LDWTFNGLWA RKNDLPYLKA VHGKHWQPEG SLGYDEDTSK LWWDAFQEMQ
     TYHDQQRNAD LY