ID   MU172_SCHPO             Reviewed;         331 AA.
AC   Q9P6R4;
DT   20-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   25-MAY-2022, entry version 85.
DE   RecName: Full=Meiotically up-regulated gene 172 protein;
GN   Name=mug172; ORFNames=SPBC13E7.06;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   FUNCTION IN MEIOSIS.
RX   PubMed=16303567; DOI=10.1016/j.cub.2005.10.038;
RA   Martin-Castellanos C., Blanco M., Rozalen A.E., Perez-Hidalgo L.,
RA   Garcia A.I., Conde F., Mata J., Ellermeier C., Davis L., San-Segundo P.,
RA   Smith G.R., Moreno S.;
RT   "A large-scale screen in S. pombe identifies seven novel genes required for
RT   critical meiotic events.";
RL   Curr. Biol. 15:2056-2062(2005).
RN   [3]
RP   SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX   PubMed=16823372; DOI=10.1038/nbt1222;
RA   Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA   Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA   Yoshida M.;
RT   "ORFeome cloning and global analysis of protein localization in the fission
RT   yeast Schizosaccharomyces pombe.";
RL   Nat. Biotechnol. 24:841-847(2006).
CC   -!- FUNCTION: Has a role in meiosis. {ECO:0000269|PubMed:16303567}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:16823372}.
CC   -!- SIMILARITY: Belongs to the ADIP family. {ECO:0000305}.
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DR   EMBL; CU329671; CAB89881.1; -; Genomic_DNA.
DR   RefSeq; NP_596261.1; NM_001022181.2.
DR   AlphaFoldDB; Q9P6R4; -.
DR   SMR; Q9P6R4; -.
DR   BioGRID; 276454; 68.
DR   STRING; 4896.SPBC13E7.06.1; -.
DR   MaxQB; Q9P6R4; -.
DR   PaxDb; Q9P6R4; -.
DR   PRIDE; Q9P6R4; -.
DR   EnsemblFungi; SPBC13E7.06.1; SPBC13E7.06.1:pep; SPBC13E7.06.
DR   GeneID; 2539908; -.
DR   KEGG; spo:SPBC13E7.06; -.
DR   PomBase; SPBC13E7.06; -.
DR   VEuPathDB; FungiDB:SPBC13E7.06; -.
DR   HOGENOM; CLU_794913_0_0_1; -.
DR   InParanoid; Q9P6R4; -.
DR   OMA; HANAPIL; -.
DR   PhylomeDB; Q9P6R4; -.
DR   PRO; PR:Q9P6R4; -.
DR   Proteomes; UP000002485; Chromosome II.
DR   GO; GO:0005737; C:cytoplasm; HDA:PomBase.
DR   GO; GO:0072686; C:mitotic spindle; IDA:PomBase.
DR   GO; GO:0044732; C:mitotic spindle pole body; IDA:PomBase.
DR   GO; GO:1990811; C:MWP complex; IDA:PomBase.
DR   GO; GO:0005634; C:nucleus; IDA:PomBase.
DR   GO; GO:0051321; P:meiotic cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:1990810; P:microtubule anchoring at mitotic spindle pole body; IMP:PomBase.
DR   GO; GO:0000070; P:mitotic sister chromatid segregation; IMP:PomBase.
DR   GO; GO:1902440; P:protein localization to mitotic spindle pole body; IMP:PomBase.
DR   InterPro; IPR021622; Afadin/alpha-actinin-bd.
DR   Pfam; PF11559; ADIP; 1.
PE   1: Evidence at protein level;
KW   Coiled coil; Cytoplasm; Meiosis; Reference proteome.
FT   CHAIN           1..331
FT                   /note="Meiotically up-regulated gene 172 protein"
FT                   /id="PRO_0000278517"
FT   COILED          72..166
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   331 AA;  38449 MW;  AEBE8EB8055BFE2D CRC64;
     MTTPIVFCNP SNIEESLLYI NKSLFSKGVI QAEKLRLSHD IRDNCNIVNI IYRLLRATDE
     ERLEKESLLD AIKNNEYEKQ RDNNTIKRLK NELELYQNEC QLQLNKVRTL ERDQAELITQ
     NKGLKDVNAK NELTLKALKN QLSVSLRQHE QQMETLKGNY GLVKARKGRN LNSMLIVKEP
     IKQNTNAPIL PETASFLQQN DENSNFLNSR VNNDEFQLLK GLNNELKKSN GTLLTCLSGT
     LNSLVEMLSP LYERPNSNPF EVCELNAILL DAKIQNQLLF IRNLLHERKY VSIDELDAIL
     EENEKNKHLI NILQKENKRV FEFLTNMHDK F