MU178_SCHPO
ID MU178_SCHPO Reviewed; 225 AA.
AC O43006;
DT 19-JUL-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-1998, sequence version 1.
DT 25-MAY-2022, entry version 94.
DE RecName: Full=Meiotically up-regulated gene 178 protein;
GN Name=mug178; ORFNames=SPBC2G2.07c;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP FUNCTION IN MEIOSIS.
RX PubMed=16303567; DOI=10.1016/j.cub.2005.10.038;
RA Martin-Castellanos C., Blanco M., Rozalen A.E., Perez-Hidalgo L.,
RA Garcia A.I., Conde F., Mata J., Ellermeier C., Davis L., San-Segundo P.,
RA Smith G.R., Moreno S.;
RT "A large-scale screen in S. pombe identifies seven novel genes required for
RT critical meiotic events.";
RL Curr. Biol. 15:2056-2062(2005).
CC -!- FUNCTION: Has a role in meiosis. {ECO:0000269|PubMed:16303567}.
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DR EMBL; CU329671; CAA17887.1; -; Genomic_DNA.
DR PIR; T40146; T40146.
DR RefSeq; NP_596436.1; NM_001022355.2.
DR AlphaFoldDB; O43006; -.
DR BioGRID; 276995; 36.
DR STRING; 4896.SPBC2G2.07c.1; -.
DR MaxQB; O43006; -.
DR PaxDb; O43006; -.
DR EnsemblFungi; SPBC2G2.07c.1; SPBC2G2.07c.1:pep; SPBC2G2.07c.
DR GeneID; 2540467; -.
DR KEGG; spo:SPBC2G2.07c; -.
DR PomBase; SPBC2G2.07c; mug178.
DR VEuPathDB; FungiDB:SPBC2G2.07c; -.
DR eggNOG; ENOG502SBK0; Eukaryota.
DR HOGENOM; CLU_1185618_0_0_1; -.
DR OMA; EDYDKFA; -.
DR PRO; PR:O43006; -.
DR Proteomes; UP000002485; Chromosome II.
DR GO; GO:0005763; C:mitochondrial small ribosomal subunit; ISO:PomBase.
DR GO; GO:0003735; F:structural constituent of ribosome; ISO:PomBase.
DR GO; GO:0051321; P:meiotic cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0070124; P:mitochondrial translational initiation; IBA:GO_Central.
DR InterPro; IPR016712; Mt_Rbsml_MRP51_fun.
DR PANTHER; PTHR28058; PTHR28058; 1.
DR Pfam; PF11709; Mit_ribos_Mrp51; 1.
PE 1: Evidence at protein level;
KW Meiosis; Reference proteome.
FT CHAIN 1..225
FT /note="Meiotically up-regulated gene 178 protein"
FT /id="PRO_0000116520"
SQ SEQUENCE 225 AA; 25672 MW; 5CA71BAC44B079BE CRC64;
MKFPDLLRCS RAVSLARPDL PRNSPDVYDT KIPILQAITA KKCQRFRGDW GAKRKLPILK
NRHISIQKFD TFEHQCAFIS SDRFVRTLKR IYDLKLPVPL NDYEQISPYL LQKYNTFSSS
NPKSRPTLPP GILYAKLKLL DSFSDSEKKR LSLVSFIQTK KVPLPFTYGK FAPDSKECLF
GVSGVIAATS LKGITSTKNR YVIRSLNVDE TGKTIPNITR ENRSI