MU191_SCHPO
ID MU191_SCHPO Reviewed; 442 AA.
AC O14131;
DT 20-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1998, sequence version 1.
DT 03-AUG-2022, entry version 118.
DE RecName: Full=Meiotically up-regulated gene 191 protein;
GN Name=mug191; ORFNames=SPAC3C7.05c;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP FUNCTION IN MEIOSIS.
RX PubMed=16303567; DOI=10.1016/j.cub.2005.10.038;
RA Martin-Castellanos C., Blanco M., Rozalen A.E., Perez-Hidalgo L.,
RA Garcia A.I., Conde F., Mata J., Ellermeier C., Davis L., San-Segundo P.,
RA Smith G.R., Moreno S.;
RT "A large-scale screen in S. pombe identifies seven novel genes required for
RT critical meiotic events.";
RL Curr. Biol. 15:2056-2062(2005).
RN [3]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=16823372; DOI=10.1038/nbt1222;
RA Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA Yoshida M.;
RT "ORFeome cloning and global analysis of protein localization in the fission
RT yeast Schizosaccharomyces pombe.";
RL Nat. Biotechnol. 24:841-847(2006).
RN [4]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-361, AND IDENTIFICATION BY
RP MASS SPECTROMETRY.
RX PubMed=18257517; DOI=10.1021/pr7006335;
RA Wilson-Grady J.T., Villen J., Gygi S.P.;
RT "Phosphoproteome analysis of fission yeast.";
RL J. Proteome Res. 7:1088-1097(2008).
CC -!- FUNCTION: Has a role in meiosis. {ECO:0000269|PubMed:16303567}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus
CC {ECO:0000269|PubMed:16823372}.
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DR EMBL; CU329670; CAB16736.1; -; Genomic_DNA.
DR PIR; T38691; T38691.
DR RefSeq; NP_593606.1; NM_001019037.2.
DR AlphaFoldDB; O14131; -.
DR SMR; O14131; -.
DR BioGRID; 279620; 4.
DR STRING; 4896.SPAC3C7.05c.1; -.
DR CAZy; GH76; Glycoside Hydrolase Family 76.
DR iPTMnet; O14131; -.
DR MaxQB; O14131; -.
DR PaxDb; O14131; -.
DR PRIDE; O14131; -.
DR EnsemblFungi; SPAC3C7.05c.1; SPAC3C7.05c.1:pep; SPAC3C7.05c.
DR GeneID; 2543191; -.
DR KEGG; spo:SPAC3C7.05c; -.
DR PomBase; SPAC3C7.05c; mug191.
DR VEuPathDB; FungiDB:SPAC3C7.05c; -.
DR eggNOG; ENOG502QR9C; Eukaryota.
DR HOGENOM; CLU_040051_1_0_1; -.
DR InParanoid; O14131; -.
DR OMA; RYWRDPS; -.
DR PhylomeDB; O14131; -.
DR PRO; PR:O14131; -.
DR Proteomes; UP000002485; Chromosome I.
DR GO; GO:0031362; C:anchored component of external side of plasma membrane; ISO:PomBase.
DR GO; GO:0005829; C:cytosol; HDA:PomBase.
DR GO; GO:0005634; C:nucleus; HDA:PomBase.
DR GO; GO:0008496; F:mannan endo-1,6-alpha-mannosidase activity; ISM:PomBase.
DR GO; GO:0051692; P:cellular oligosaccharide catabolic process; IC:PomBase.
DR GO; GO:0009272; P:fungal-type cell wall biogenesis; ISO:PomBase.
DR GO; GO:0051321; P:meiotic cell cycle; IEA:UniProtKB-KW.
DR InterPro; IPR008928; 6-hairpin_glycosidase_sf.
DR InterPro; IPR005198; Glyco_hydro_76.
DR Pfam; PF03663; Glyco_hydro_76; 1.
DR SUPFAM; SSF48208; SSF48208; 1.
PE 1: Evidence at protein level;
KW Cytoplasm; Meiosis; Nucleus; Phosphoprotein; Reference proteome.
FT CHAIN 1..442
FT /note="Meiotically up-regulated gene 191 protein"
FT /id="PRO_0000278631"
FT REGION 416..442
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 361
FT /note="Phosphothreonine"
FT /evidence="ECO:0000269|PubMed:18257517"
SQ SEQUENCE 442 AA; 49780 MW; 67289BC3231B7A3C CRC64;
MSENVYLNEA LNVVDQCFKT FFDKYTDRMG SAFACSGTID KDHIFLVWSV AVYAEAMADS
LRYTSKFERK FEHVFQALKK YWSPVFNACC AFHYFEGNDD VYYDDNAQVA IGLATAGYYT
TNSSRRDHYV SRAESIISLI INKGWNQQRG GIAWHTRTTG PPWTNLNACS TSMSAVAALR
LALALDDPNK KQHLVSFAWN CVRWIQENLL DENHIVCDGL SLKDGKWVLD KARFTYNTGT
TMTAMSLLMG LGEFTKGLQD IEKLPTYLED MARGALDTNG PLYDQSCNGS FKVWSDNTFF
AQHLSEGLMT FSYAMPSSAL AKPAQKMVLD QADFLMKYLR IPKEGLYYRN FGLYKLSPEL
TASFNKFFNA NKQFQPDKDE RIQQEGPVEQ RPLCPTLIGS AGAARMLFSA AEIVNRNNPS
SGESTTLPQP SHGKKDKDCV IS
