MUC19_MOUSE
ID MUC19_MOUSE Reviewed; 7524 AA.
AC Q6PZE0; A7UN62; A7UN63; A7UN64; A7UN66; Q6P7U5; Q6Y0X6; Q80UR5;
DT 01-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT 25-OCT-2004, sequence version 2.
DT 03-AUG-2022, entry version 111.
DE RecName: Full=Mucin-19;
DE Short=MUC-19;
DE AltName: Full=Gel-forming secreted mucin-19;
DE AltName: Full=Sublingual apomucin;
DE Flags: Precursor;
GN Name=Muc19;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], AND TISSUE SPECIFICITY.
RC STRAIN=NFS; TISSUE=Sublingual gland;
RX PubMed=15340121; DOI=10.1152/physiolgenomics.00161.2004;
RA Culp D.J., Latchney L.R., Fallon M.A., Denny P.A., Denny P.C.,
RA Couwenhoven R.I., Chuang S.;
RT "The gene encoding mouse Muc19: cDNA, genomic organization and relationship
RT to Smgc.";
RL Physiol. Genomics 19:303-318(2004).
RN [2]
RP NUCLEOTIDE SEQUENCE [MRNA] OF 6711-7524, AND TISSUE SPECIFICITY.
RC STRAIN=Swiss Webster; TISSUE=Sublingual gland;
RX PubMed=12847143; DOI=10.1152/physiolgenomics.00151.2002;
RA Fallon M.A., Latchney L.R., Hand A.R., Johar A., Denny P.A., Georgel P.T.,
RA Denny P.C., Culp D.J.;
RT "The sld mutation is specific for sublingual salivary mucous cells and
RT disrupts apomucin gene expression.";
RL Physiol. Genomics 14:95-106(2003).
RN [3]
RP NUCLEOTIDE SEQUENCE [MRNA] OF 6918-7524, AND TISSUE SPECIFICITY.
RC STRAIN=C57BL/6 X DBA/2;
RX PubMed=12882755; DOI=10.1165/rcmb.2003-0103oc;
RA Chen Y., Zhao Y.H., Kalaslavadi T.B., Hamati E., Nehrke K., Le A.D.,
RA Ann D.K., Wu R.;
RT "Genome-wide search and identification of a novel gel-forming mucin
RT MUC19/Muc19 in glandular tissues.";
RL Am. J. Respir. Cell Mol. Biol. 30:155-165(2004).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 7276-7524.
RC STRAIN=FVB/N; TISSUE=Salivary gland;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- FUNCTION: May function in ocular mucus homeostasis. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=6;
CC Comment=Isoform 1 and isoform 2-6 share the first 17 amino acid
CC residues that correspond to the signal sequence.;
CC Name=1; Synonyms=Mucin-19;
CC IsoId=Q6PZE0-1; Sequence=Displayed;
CC Name=2; Synonyms=Smgc;
CC IsoId=Q6JHY2-1; Sequence=External;
CC Name=3;
CC IsoId=Q6JHY2-2; Sequence=External;
CC Name=4;
CC IsoId=Q6JHY2-3; Sequence=External;
CC Name=5; Synonyms=t-Smgc;
CC IsoId=Q6JHY2-4; Sequence=External;
CC Name=6;
CC IsoId=Q6JHY2-5; Sequence=External;
CC -!- TISSUE SPECIFICITY: Specifically expressed in sublingual salivary
CC glands. Expressed by mucous cells of the submandibular gland and
CC submucosal gland of the trachea. Expression is altered in sld
CC (sublingual gland differentiation arrest) mutants.
CC {ECO:0000269|PubMed:12847143, ECO:0000269|PubMed:12882755,
CC ECO:0000269|PubMed:15340121}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAO49800.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Sequence of unknown origin in the N-terminal part.; Evidence={ECO:0000305};
CC -!- WEB RESOURCE: Name=Mucin database;
CC URL="http://www.medkem.gu.se/mucinbiology/databases/";
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DR EMBL; AY570293; AAS77382.2; -; mRNA.
DR EMBL; EU089955; ABU50842.1; -; mRNA.
DR EMBL; EU089956; ABU50843.1; -; mRNA.
DR EMBL; EU089957; ABU50844.1; -; mRNA.
DR EMBL; EU089959; ABU50846.1; -; mRNA.
DR EMBL; AY172172; AAO38851.1; -; mRNA.
DR EMBL; AY193891; AAO49800.1; ALT_SEQ; mRNA.
DR EMBL; BC061502; AAH61502.1; -; mRNA.
DR RefSeq; NP_997126.2; NM_207243.2.
DR SMR; Q6PZE0; -.
DR BioGRID; 232106; 3.
DR STRING; 10090.ENSMUSP00000085907; -.
DR PhosphoSitePlus; Q6PZE0; -.
DR EPD; Q6PZE0; -.
DR MaxQB; Q6PZE0; -.
DR PaxDb; Q6PZE0; -.
DR PRIDE; Q6PZE0; -.
DR ProteomicsDB; 290071; -. [Q6PZE0-1]
DR Antibodypedia; 66808; 5 antibodies from 4 providers.
DR Ensembl; ENSMUST00000239545; ENSMUSP00000159433; ENSMUSG00000118670. [Q6PZE0-1]
DR UCSC; uc007xie.1; mouse. [Q6PZE0-1]
DR MGI; MGI:2676278; Muc19.
DR eggNOG; KOG1216; Eukaryota.
DR GeneTree; ENSGT00940000164528; -.
DR InParanoid; Q6PZE0; -.
DR OMA; TTGEYEF; -.
DR OrthoDB; 12226at2759; -.
DR Reactome; R-MMU-913709; O-linked glycosylation of mucins.
DR Reactome; R-MMU-977068; Termination of O-glycan biosynthesis.
DR BioGRID-ORCS; 239611; 1 hit in 20 CRISPR screens.
DR ChiTaRS; Muc19; mouse.
DR Proteomes; UP000000589; Chromosome 15.
DR RNAct; Q6PZE0; protein.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0060689; P:cell differentiation involved in salivary gland development; IMP:MGI.
DR GO; GO:0002244; P:hematopoietic progenitor cell differentiation; IGI:MGI.
DR GO; GO:0050728; P:negative regulation of inflammatory response; IMP:MGI.
DR InterPro; IPR006207; Cys_knot_C.
DR InterPro; IPR036084; Ser_inhib-like_sf.
DR InterPro; IPR002919; TIL_dom.
DR InterPro; IPR014853; Unchr_dom_Cys-rich.
DR InterPro; IPR001007; VWF_dom.
DR InterPro; IPR001846; VWF_type-D.
DR Pfam; PF08742; C8; 3.
DR Pfam; PF01826; TIL; 1.
DR Pfam; PF00094; VWD; 3.
DR SMART; SM00832; C8; 2.
DR SMART; SM00041; CT; 1.
DR SMART; SM00214; VWC; 2.
DR SMART; SM00215; VWC_out; 2.
DR SMART; SM00216; VWD; 3.
DR SUPFAM; SSF57567; SSF57567; 3.
DR PROSITE; PS01185; CTCK_1; 1.
DR PROSITE; PS01225; CTCK_2; 1.
DR PROSITE; PS01208; VWFC_1; 1.
DR PROSITE; PS50184; VWFC_2; 1.
DR PROSITE; PS51233; VWFD; 3.
PE 2: Evidence at transcript level;
KW Alternative splicing; Disulfide bond; Reference proteome; Repeat; Secreted;
KW Signal.
FT SIGNAL 1..20
FT /evidence="ECO:0000255"
FT CHAIN 21..7524
FT /note="Mucin-19"
FT /id="PRO_5000093121"
FT DOMAIN 55..225
FT /note="VWFD 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00580"
FT DOMAIN 298..353
FT /note="TIL"
FT DOMAIN 392..568
FT /note="VWFD 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00580"
FT DOMAIN 851..1025
FT /note="VWFD 3"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00580"
FT REPEAT 1321..1483
FT /note="1"
FT REPEAT 1484..1646
FT /note="2"
FT REPEAT 1647..1809
FT /note="3"
FT REPEAT 1810..1972
FT /note="4"
FT REPEAT 1973..2135
FT /note="5"
FT REPEAT 2136..2298
FT /note="6"
FT REPEAT 2299..2461
FT /note="7"
FT REPEAT 2462..2624
FT /note="8"
FT REPEAT 2625..2787
FT /note="9"
FT REPEAT 2788..2950
FT /note="10"
FT REPEAT 2951..3113
FT /note="11"
FT REPEAT 3114..3276
FT /note="12"
FT REPEAT 3277..3439
FT /note="13"
FT REPEAT 3440..3602
FT /note="14"
FT REPEAT 3603..3765
FT /note="15"
FT REPEAT 3766..3928
FT /note="16"
FT REPEAT 3929..4091
FT /note="17"
FT REPEAT 4092..4254
FT /note="18"
FT REPEAT 4255..4417
FT /note="19"
FT REPEAT 4418..4580
FT /note="20"
FT REPEAT 4581..4743
FT /note="21"
FT REPEAT 4744..4906
FT /note="22"
FT REPEAT 4907..5069
FT /note="23"
FT REPEAT 5070..5232
FT /note="24"
FT REPEAT 5233..5395
FT /note="25"
FT REPEAT 5396..5558
FT /note="26"
FT REPEAT 5559..5721
FT /note="27"
FT REPEAT 5722..5884
FT /note="28"
FT REPEAT 5885..6047
FT /note="29"
FT REPEAT 6048..6210
FT /note="30"
FT REPEAT 6211..6373
FT /note="31"
FT REPEAT 6374..6536
FT /note="32"
FT REPEAT 6537..6699
FT /note="33"
FT REPEAT 6700..6862
FT /note="34"
FT REPEAT 6863..7025
FT /note="35"
FT REPEAT 7026..7188
FT /note="36"
FT DOMAIN 7302..7368
FT /note="VWFC 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00220"
FT DOMAIN 7370..7432
FT /note="VWFC 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00220"
FT DOMAIN 7435..7519
FT /note="CTCK"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00039"
FT REGION 20..47
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1244..7217
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1321..7188
FT /note="Approximate repeats"
FT REGION 7249..7297
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 21..45
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1244..1302
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1318..7217
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 7249..7292
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 79..224
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00580"
FT DISULFID 394..529
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00580"
FT DISULFID 434..442
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00580"
FT DISULFID 853..989
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00580"
FT DISULFID 875..1024
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00580"
FT DISULFID 884..986
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00580"
FT DISULFID 900..907
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00580"
FT DISULFID 7435..7482
FT /evidence="ECO:0000250"
FT DISULFID 7449..7496
FT /evidence="ECO:0000250"
FT DISULFID 7458..7512
FT /evidence="ECO:0000250"
FT DISULFID 7462..7514
FT /evidence="ECO:0000250"
FT DISULFID ?..7518
FT /evidence="ECO:0000250"
FT CONFLICT 7111
FT /note="V -> A (in Ref. 3; AAO49800)"
FT /evidence="ECO:0000305"
FT CONFLICT 7178
FT /note="P -> L (in Ref. 2; AAO38851 and 3; AAO49800)"
FT /evidence="ECO:0000305"
FT CONFLICT 7293
FT /note="E -> V (in Ref. 2; AAO38851, 3; AAO49800 and 4;
FT AAH61502)"
FT /evidence="ECO:0000305"
FT CONFLICT 7333
FT /note="V -> L (in Ref. 2; AAO38851 and 4; AAH61502)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 7524 AA; 693499 MW; B99A4519CE1EF6D4 CRC64;
MKLILLYLAV VLCFVGKGAA RSPTTTRTPT PSTSEKASHV PEATPTYSEA NEVAGEATMW
GKDKYKALNG HIFSFESECT FTFCRDCAEP GGDFNIEIKK HKNGDIEEIK ALIDDVEILV
VRNSISVNEE RVKVPFSNKM IHIKKQGNHY SLKTRRRILS LKWSKDKLSL ILYSHYTTCG
LCGNFDSVPG DDVNEHIASS KISNDCPSPL SRSNEVCEDG VQYCDKIIET YFEKCSKVSP
LSREYKNVCA DEYCRKGGGK QTTCDTYSEL ARLCAYDGPG DYEHWRDDSA VVCAKEQCPG
KHIYKECGPS NPPTCSNVAP FQDSECVSGC TCPEGYLLDD IGEKGKCVLK EKCPCESNGK
VYKPGKVREG PCGSRCTCQE AKWSCTEARC PGICKVEGSS FTTFDDNKFS HPGDCHFLAV
HNDEISISVE IHPCGNGQTG SCLTSVMVLQ NSSSSSNRYV FNRDGTVTKD GVIIKGYYYS
DDVQIFNSSS SYMQAEILSH IKLQIQLAPR MQLYVSLAPN TSTDTVGLCG SFNNKAEDDF
MSSQNILEST AQAFANSWEM MPCSEGSPSS CVSIETEKFA ESNCEILLSS SGPFAACHQT
VNPKFYHEEC KKYTCSCENG QDCLCTVLGN YVKACAEKEI YLVGWRDGLC EVSCPSGLVF
NYKVKTCNSS CRSLSARDRS CDIEDIPVDG CTCPDGMYQN NEGNCVQKSE CDCYVNDEIV
QPGKSILIDD NKCVCQDGVL HCQTPLDLTL QNCSRGAEYI DCKDPKAQRR TERTCATRNI
PDFEGDLPCK RGCYCPVGMV RNSKGICIHP DDCPCSFGDR EYEQGSVTSV GCNECTCIKG
SWNCTQNECQ STCHVYGEGH FRTFDGESYS FDGLCQYTFL EDYCGQENGT FRILIESVPC
CENGLTCSRK VIVTFQDQNI ILQDGKVTAV QTAESTDCRE RSANLYSIHT VGLYLIVKLL
NGIILIWDKY TKVSVILDPS WQNKVCGLCG NNNGDLKDDF TTRHSSVAAG ALEFANSWKT
SQECSDTVTQ SFPCDSNPYC KAWAEKRCEI LRDDTFRDCH SKVDPTTYYD ACIEEACSCD
MEGKYLGFCT AVAMYAEACN AAGVCVSWRK PNLCPVYCDY YNAPGECSWH YEPCGTVTAK
TCKDQVIGQK FSSLLEGCYA KCPENAPYLD ENTMKCVQLS ECSCFYNDVI PAGGAVVDDC
GRTCSCSAGE LECSETPPNS TTTTTATTAA VSTATTTSVL STSAAATRAS SSTSGSVETS
VPATTSTSKA QAHITTASST ETSALNSTAV YPKATTREGL LSSSGPGAFV AERPDNTPRP
AVSTTSAGST SARAATTSPG GSSGSSAPAS STSGRAATTT STSAATTTTT TTATTVGSAG
SSAPTASSTA AGSGLREAAN ATSAPASTSG QPGASTGSSG TSSSVSSTAA ATTAGTTTAA
SNETSAPAST AGPTSSATTA APASSSASSA TTPAETAGST TGPAVSTTSA GSTSARAATT
SPGGSSGSSA PASSTSGRAA TTTSTATTTT TTTTTATTVG SAGSSAPTAS STAAGSGLRE
AANATSAPAS TSGQPGASTG SSGTSSSVSS TAAATTAGTT TAASNETSAP ASTAGPTSSA
TTAAPASSSA SSATTPAETA GSTTGPAVST TSAGSTSARA ATTSPGGSSG SSAPASSTSG
RAATTTSTAT TTTTTTTTAT TVGSAGSSAP TASSTAAGSG LREAANATSA PASTSGQPGA
STGSSGTSSS VSSTAAATTA GTTTAASNET SAPASTAGPT SSATTAAPAS SSASSATTPA
ETAGSTTGPA VSTTSAGSTS ARAATTSPGG SSGSSAPASS TSGRAATTTS TATTTTTTTT
TATTVGSAGS SAPTASSTAA GSGLREAANA TSAPASTSGQ PGASTGSSGT SSSVSSTAAA
TTAGTTTAAS NETSAPASTA GPTSSATTAA PASSSASSAT TPAETAGSTT GPAVSTTSAG
STSARAATTS PGGSSGSSAP ASSTSGRAAT TTSTATTTTT TTTTATTVGS AGSSAPTASS
TAAGSGLREA ANATSAPAST SGQPGASTGS SGTSSSVSST AAATTAGTTT AASNETSAPA
STAGPTSSAT TAAPASSSAS SATTPAETAG STTGPAVSTT SAGSTSARAA TTSPGGSSGS
SAPASSTSGR AATTTSTATT TTTTTTTATT VGSAGSSAPT ASSTAAGSGL REAANATSAP
ASTSGQPGAS TGSSGTSSSV SSTAAATTAG TTTAASNETS APASTAGPTS SATTAAPASS
SASSATTPAE TAGSTTGPAV STTSAGSTSA RAATTSPGGS SGSSAPASST SGRAATTTST
ATTTTTTTTT ATTVGSAGSS APTASSTAAG SGLREAANAT SAPASTSGQP GASTGSSGTS
SSVSSTAAAT TAGTTTAASN ETSAPASTAG PTSSATTAAP ASSSASSATT PAETAGSTTG
PAVSTTSAGS TSARAATTSP GGSSGSSAPA SSTSGRAATT TSTATTTTTT TTTATTVGSA
GSSAPTASST AAGSGLREAA NATSAPASTS GQPGASTGSS GTSSSVSSTA AATTAGTTTA
ASNETSAPAS TAGPTSSATT AAPASSSASS ATTPAETAGS TTGPAVSTTS AGSTSARAAT
TSPGGSSGSS APASSTSGRA ATTTSTATTT TTTTTTATTV GSAGSSAPTA SSTAAGSGLR
EAANATSAPA STSGQPGAST GSSGTSSSVS STAAATTAGT TTAASNETSA PASTAGPTSS
ATTAAPASSS ASSATTPAET AGSTTGPAVS TTSAGSTSAR AATTSPGGSS GSSAPASSTS
GRAATTTSTA TTTTTTTTTA TTVGSAGSSA PTASSTAAGS GLREAANATS APASTSGQPG
ASTGSSGTSS SVSSTAAATT AGTTTAASNE TSAPASTAGP TSSATTAAPA SSSASSATTP
AETAGSTTGP AVSTTSAGST SARAATTSPG GSSGSSAPAS STSGRAATTT STATTTTTTT
TTATTVGSAG SSAPTASSTA AGSGLREAAN ATSAPASTSG QPGASTGSSG TSSSVSSTAA
ATTAGTTTAA SNETSAPAST AGPTSSATTA APASSSASSA TTPAETAGST TGPAVSTTSA
GSTSARAATT SPGGSSGSSA PASSTSGRAA TTTSTATTTT TTTTTATTVG SAGSSAPTAS
STAAGSGLRE AANATSAPAS TSGQPGASTG SSGTSSSVSS TAAATTAGTT TAASNETSAP
ASTAGPTSSA TTAAPASSSA SSATTPAETA GSTTGPAVST TSAGSTSARA ATTSPGGSSG
SSAPASSTSG RAATTTSTAT TTTTTTTTAT TVGSAGSSAP TASSTAAGSG LREAANATSA
PASTSGQPGA STGSSGTSSS VSSTAAATTA GTTTAASNET SAPASTAGPT SSATTAAPAS
SSASSATTPA ETAGSTTGPA VSTTSAGSTS ARAATTSPGG SSGSSAPASS TSGRAATTTS
TATTTTTTTT TATTVGSAGS SAPTASSTAA GSGLREAANA TSAPASTSGQ PGASTGSSGT
SSSVSSTAAA TTAGTTTAAS NETSAPASTA GPTSSATTAA PASSSASSAT TPAETAGSTT
GPAVSTTSAG STSARAATTS PGGSSGSSAP ASSTSGRAAT TTSTATTTTT TTTTATTVGS
AGSSAPTASS TAAGSGLREA ANATSAPAST SGQPGASTGS SGTSSSVSST AAATTAGTTT
AASNETSAPA STAGPTSSAT TAAPASSSAS SATTPAETAG STTGPAVSTT SAGSTSARAA
TTSPGGSSGS SAPASSTSGR AATTTSTATT TTTTTTTATT VGSAGSSAPT ASSTAAGSGL
REAANATSAP ASTSGQPGAS TGSSGTSSSV SSTAAATTAG TTTAASNETS APASTAGPTS
SATTAAPASS SASSATTPAE TAGSTTGPAV STTSAGSTSA RAATTSPGGS SGSSAPASST
SGRAATTTST ATTTTTTTTT ATTVGSAGSS APTASSTAAG SGLREAANAT SAPASTSGQP
GASTGSSGTS SSVSSTAAAT TAGTTTAASN ETSAPASTAG PTSSATTAAP ASSSASSATT
PAETAGSTTG PAVSTTSAGS TSARAATTSP GGSSGSSAPA SSTSGRAATT TSTATTTTTT
TTTATTVGSA GSSAPTASST AAGSGLREAA NATSAPASTS GQPGASTGSS GTSSSVSSTA
AATTAGTTTA ASNETSAPAS TAGPTSSATT AAPASSSASS ATTPAETAGS TTGPAVSTTS
AGSTSARAAT TSPGGSSGSS APASSTSGRA ATTTSTATTT TTTTTTATTV GSAGSSAPTA
SSTAAGSGLR EAANATSAPA STSGQPGAST GSSGTSSSVS STAAATTAGT TTAASNETSA
PASTAGPTSS ATTAAPASSS ASSATTPAET AGSTTGPAVS TTSAGSTSAR AATTSPGGSS
GSSAPASSTS GRAATTTSTA TTTTTTTTTA TTVGSAGSSA PTASSTAAGS GLREAANATS
APASTSGQPG ASTGSSGTSS SVSSTAAATT AGTTTAASNE TSAPASTAGP TSSATTAAPA
SSSASSATTP AETAGSTTGP AVSTTSAGST SARAATTSPG GSSGSSAPAS STSGRAATTT
STATTTTTTT TTATTVGSAG SSAPTASSTA AGSGLREAAN ATSAPASTSG QPGASTGSSG
TSSSVSSTAA ATTAGTTTAA SNETSAPAST AGPTSSATTA APASSSASSA TTPAETAGST
TGPAVSTTSA GSTSARAATT SPGGSSGSSA PASSTSGRAA TTTSTATTTT TTTTTATTVG
SAGSSAPTAS STAAGSGLRE AANATSAPAS TSGQPGASTG SSGTSSSVSS TAAATTAGTT
TAASNETSAP ASTAGPTSSA TTAAPASSSA SSATTPAETA GSTTGPAVST TSAGSTSARA
ATTSPGGSSG SSAPASSTSG RAATTTSTAT TTTTTTTTAT TVGSAGSSAP TASSTAAGSG
LREAANATSA PASTSGQPGA STGSSGTSSS VSSTAAATTA GTTTAASNET SAPASTAGPT
SSATTAAPAS SSASSATTPA ETAGSTTGPA VSTTSAGSTS ARAATTSPGG SSGSSAPASS
TSGRAATTTS TATTTTTTTT TATTVGSAGS SAPTASSTAA GSGLREAANA TSAPASTSGQ
PGASTGSSGT SSSVSSTAAA TTAGTTTAAS NETSAPASTA GPTSSATTAA PASSSASSAT
TPAETAGSTT GPAVSTTSAG STSARAATTS PGGSSGSSAP ASSTSGRAAT TTSTATTTTT
TTTTATTVGS AGSSAPTASS TAAGSGLREA ANATSAPAST SGQPGASTGS SGTSSSVSST
AAATTAGTTT AASNETSAPA STAGPTSSAT TAAPASSSAS SATTPAETAG STTGPAVSTT
SAGSTSARAA TTSPGGSSGS SAPASSTSGR AATTTSTATT TTTTTTTATT VGSAGSSAPT
ASSTAAGSGL REAANATSAP ASTSGQPGAS TGSSGTSSSV SSTAAATTAG TTTAASNETS
APASTAGPTS SATTAAPASS SASSATTPAE TAGSTTGPAV STTSAGSTSA RAATTSPGGS
SGSSAPASST SGRAATTTST ATTTTTTTTT ATTVGSAGSS APTASSTAAG SGLREAANAT
SAPASTSGQP GASTGSSGTS SSVSSTAAAT TAGTTTAASN ETSAPASTAG PTSSATTAAP
ASSSASSATT PAETAGSTTG PAVSTTSAGS TSARAATTSP GGSSGSSAPA SSTSGRAATT
TSTATTTTTT TTTATTVGSA GSSAPTASST AAGSGLREAA NATSAPASTS GQPGASTGSS
GTSSSVSSTA AATTAGTTTA ASNETSAPAS TAGPTSSATT AAPASSSASS ATTPAETAGS
TTGPAVSTTS AGSTSARAAT TSPGGSSGSS APASSTSGRA ATTTSTATTT TTTTTTATTV
GSAGSSAPTA SSTAAGSGLR EAANATSAPA STSGQPGAST GSSGTSSSVS STAAATTAGT
TTAASNETSA PASTAGPTSS ATTAAPASSS ASSATTPAET AGSTTGPAVS TTSAGSTSAR
AATTSPGGSS GSSAPASSTS GRAATTTSTA TTTTTTTTTA TTVGSAGSSA PTASSTAAGS
GLREAANATS APASTSGQPG ASTGSSGTSS SVSSTAAATT AGTTTAASNE TSAPASTAGP
TSSATTAAPA SSSASSATTP AETAGSTTGP AVSTTSAGST SARAATTSPG GSSGSSAPAS
STSGRAATTT STATTTTTTT TTATTVGSAG SSAPTASSTA AGSGLREAAN ATSAPASTSG
QPGASTGSSG TSSSVSSTAA ATTAGTTTAA SNETSAPAST AGPTSSATTA APASSSASSA
TTPAETAGST TGPAVSTTSA GSTSARAATT SPGGSSGSSA PASSTSGRAA TTTSTATTTT
TTTTTATTVG SAGSSAPTAS STAAGSGLRE AANATSAPAS TSGQPGASTG SSGTSSSVSS
TAAATTAGTT TAASNETSAP ASTAGPTSSA TTAAPASSSA SSATTPAETA GSTTGPAVST
TSAGSTSARA ATTSPGGSSG SSAPASSTSG RAATTTSTAT TTTTTTTTAT TVGSAGSSAP
TASSTAAGSG LREAANATSA PASTSGQPGA STGSSGTSSS VSSTAAATTA GTTTAASNET
SAPASTAGPT SSATTAAPAS SSASSATTPA ETAGSTTGPA VSTTSAGSTS ARAATTSPGG
SSGSSAPASS TSGRAATTTS TATTTTTTTT TATTVGSAGS SAPTASSTAA GSGLREAANA
TSAPASTSGQ PGASTGSSGT SSSVSSTAAA TTAGTTTAAS NETSAPASTA GPTSSATTAA
PASSSASSAT TPAETAGSTT GPAVSTTSAG STSARAATTS PGGSSGSSAP ASSTSGRAAT
TTSTATTTTT TTTTATTVGS AGSSAPTASS TAAGSGLREA ANATSAPAST SGQPGASTGS
SGTSSSVSST AAATTAGTTT AASNETSAPA STAGPTSSAT TAAPASSSAS SATTPAETAG
STTGPAVSTT SAGSTSARAA TTSPGGSSGS SAPASSTSGR AATTTSTATT TTTTTTTATT
VGSAGSSAPT ASSTAAGSGL REAANATSAP VSTSGQPGAS TGSSGTSSSV SSTAAATTAG
TTTAASNETS APASTAGPTS SATTAAPASS SASSATTPAE TAGSTTGPAV STTSAGSTSA
RAATTSPGGS SGSSSLAIST MSVSSSSFIS PSGHPVPSTA SVAFLSSPSV IKTGGTTGTT
AKSNETTGRT TSMPASTSVA PGVTTSPNIS QPECPDSLPP TPVCHGPLGE EKSPGDVWIS
NCHQCTCTEK QAVDCKPKEC PSPPTCKDGE KLMKFKSNDS CCEIGHCEPR TCLFNNTDYA
IGSSFDDPSN PCLSYTCNPT GLVAVVQDCP KQTWCAEEER IYDSNKCCYK CKNDCRTTPV
NVTVKYNGCR KRVEMARCIG ECKRSVKYNY ETFQLENSCS CCREENYEFR DIALECSDGS
TIPYRYRHTT TCSCRDQCEQ SKAS
