ID   MUCB_ECOLX              Reviewed;         420 AA.
AC   P07375;
DT   01-APR-1988, integrated into UniProtKB/Swiss-Prot.
DT   01-APR-1988, sequence version 1.
DT   25-MAY-2022, entry version 90.
DE   RecName: Full=Protein MucB;
GN   Name=mucB;
OS   Escherichia coli.
OG   Plasmid IncN pKM101.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=562;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2989816; DOI=10.1073/pnas.82.13.4331;
RA   Perry K.L., Elledge S.J., Mitchell B.B., Marsh L., Walker G.C.;
RT   "umuDC and mucAB operons whose products are required for UV light- and
RT   chemical-induced mutagenesis: UmuD, MucA, and LexA proteins share
RT   homology.";
RL   Proc. Natl. Acad. Sci. U.S.A. 82:4331-4335(1985).
CC   -!- FUNCTION: Involved in UV protection and mutation.
CC   -!- MISCELLANEOUS: The mucAB operon is the plasmid-borne analog of the
CC       E.coli umuDC operon.
CC   -!- SIMILARITY: Belongs to the DNA polymerase type-Y family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; D90147; BAA14176.1; -; Genomic_DNA.
DR   EMBL; M13388; AAA98278.1; -; Genomic_DNA.
DR   PIR; C23157; ZWECBP.
DR   AlphaFoldDB; P07375; -.
DR   SMR; P07375; -.
DR   DIP; DIP-16999N; -.
DR   GO; GO:0003684; F:damaged DNA binding; IEA:InterPro.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0009432; P:SOS response; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.1490.100; -; 1.
DR   Gene3D; 3.30.70.270; -; 1.
DR   InterPro; IPR043502; DNA/RNA_pol_sf.
DR   InterPro; IPR036775; DNA_pol_Y-fam_lit_finger_sf.
DR   InterPro; IPR017961; DNA_pol_Y-fam_little_finger.
DR   InterPro; IPR025188; DUF4113.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   InterPro; IPR001126; UmuC.
DR   Pfam; PF13438; DUF4113; 1.
DR   Pfam; PF00817; IMS; 1.
DR   Pfam; PF11799; IMS_C; 1.
DR   SUPFAM; SSF56672; SSF56672; 1.
DR   PROSITE; PS50173; UMUC; 1.
PE   3: Inferred from homology;
KW   DNA damage; DNA repair; Plasmid; SOS mutagenesis; SOS response.
FT   CHAIN           1..420
FT                   /note="Protein MucB"
FT                   /id="PRO_0000173979"
FT   DOMAIN          2..187
FT                   /note="UmuC"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00216"
SQ   SEQUENCE   420 AA;  46361 MW;  92BA722D10F7F235 CRC64;
     MFALIDVNGM YASCEQAFRP DLANRAVAVL SNNDGNIVAR NYLAKKAGLK MGDPYFKVRP
     IIERHNIAIF SSNYTLYASM SARFAAVVES LASHVEQYSI DELFVDCKGI TAAMSLDAFG
     RQLREEVRRH TTLVCGVGIA RTKTLAKLCN HAAKTWPATG GVVALDDGAR LKKLMSILPV
     AEVWGVGHRT EKALATMGIK TVLDLARADT RLIRKTFGVV LERTVRELRG EACFSLEENP
     PAKQQIVVSR SFGQRVETLT DMQQAVTGFA ARAAEKLRNE RQYCRVISVF IRTSPYSVRD
     TQYANQATEK LTVATQDSRT IIQAAQALAR IWREDIAYAK AGVMLADFSG KEAQLDLFDS
     ATPSAGSEAL MAVLDGINRR GKNQLFFAGQ GIDNSFAMRR QMLSPDYTTD WRSIPIATIK