MUCSM_CANLF
ID MUCSM_CANLF Reviewed; 89 AA.
AC P83762;
DT 01-MAR-2004, integrated into UniProtKB/Swiss-Prot.
DT 27-SEP-2004, sequence version 2.
DT 25-MAY-2022, entry version 54.
DE RecName: Full=Submaxillary mucin;
DE AltName: Full=CSM;
DE Flags: Fragment;
OS Canis lupus familiaris (Dog) (Canis familiaris).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis.
OX NCBI_TaxID=9615;
RN [1] {ECO:0000305}
RP PROTEIN SEQUENCE, AND GLYCOSYLATION.
RC TISSUE=Submandibular gland;
RX PubMed=15274643; DOI=10.1021/bi049178e;
RA Gerken T.A., Tep C., Rarick J.;
RT "Role of peptide sequence and neighboring residue glycosylation on the
RT substrate specificity of the uridine 5'-diphosphate-alpha-N-
RT acetylgalactosamine:polypeptide N-acetylgalactosaminyl transferases T1 and
RT T2: kinetic modeling of the porcine and canine submaxillary gland mucin
RT tandem repeats.";
RL Biochemistry 43:9888-9900(2004).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:15274643}.
CC -!- TISSUE SPECIFICITY: Expressed in the submaxillary salivary gland.
CC {ECO:0000269|PubMed:15274643}.
CC -!- DOMAIN: The mature protein contains tandemly repeated, identical
CC sequences. {ECO:0000269|PubMed:15274643}.
CC -!- PTM: Heavily O-glycosylated at most but not all Ser and Thr residues.
CC {ECO:0000269|PubMed:15274643}.
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DR AlphaFoldDB; P83762; -.
DR STRING; 9612.ENSCAFP00000041846; -.
DR iPTMnet; P83762; -.
DR PaxDb; P83762; -.
DR eggNOG; KOG1216; Eukaryota.
DR Proteomes; UP000002254; Unplaced.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
PE 1: Evidence at protein level;
KW Direct protein sequencing; Glycoprotein; Reference proteome; Secreted.
FT CHAIN <1..>89
FT /note="Submaxillary mucin"
FT /id="PRO_0000158962"
FT REGION 1..89
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CARBOHYD 3
FT /note="O-linked (GalNAc...) serine; partial"
FT /evidence="ECO:0000269|PubMed:15274643"
FT CARBOHYD 7
FT /note="O-linked (GalNAc...) threonine; partial"
FT /evidence="ECO:0000269|PubMed:15274643"
FT CARBOHYD 14
FT /note="O-linked (GalNAc...) threonine; partial"
FT /evidence="ECO:0000269|PubMed:15274643"
FT CARBOHYD 15
FT /note="O-linked (GalNAc...) serine; partial"
FT /evidence="ECO:0000269|PubMed:15274643"
FT CARBOHYD 23
FT /note="O-linked (GalNAc...) threonine; partial"
FT /evidence="ECO:0000269|PubMed:15274643"
FT CARBOHYD 25
FT /note="O-linked (GalNAc...) serine; partial"
FT /evidence="ECO:0000269|PubMed:15274643"
FT CARBOHYD 27
FT /note="O-linked (GalNAc...) threonine; partial"
FT /evidence="ECO:0000269|PubMed:15274643"
FT CARBOHYD 29
FT /note="O-linked (GalNAc...) serine; partial"
FT /evidence="ECO:0000269|PubMed:15274643"
FT CARBOHYD 34
FT /note="O-linked (GalNAc...) threonine; partial"
FT /evidence="ECO:0000269|PubMed:15274643"
FT CARBOHYD 38
FT /note="O-linked (GalNAc...) serine; partial"
FT /evidence="ECO:0000269|PubMed:15274643"
FT CARBOHYD 42
FT /note="O-linked (GalNAc...) threonine; partial"
FT /evidence="ECO:0000269|PubMed:15274643"
FT CARBOHYD 47
FT /note="O-linked (GalNAc...) serine; partial"
FT /evidence="ECO:0000269|PubMed:15274643"
FT CARBOHYD 49
FT /note="O-linked (GalNAc...) serine; partial"
FT /evidence="ECO:0000269|PubMed:15274643"
FT CARBOHYD 50
FT /note="O-linked (GalNAc...) threonine; partial"
FT /evidence="ECO:0000269|PubMed:15274643"
FT CARBOHYD 54
FT /note="O-linked (GalNAc...) serine; partial"
FT /evidence="ECO:0000269|PubMed:15274643"
FT CARBOHYD 59
FT /note="O-linked (GalNAc...) threonine; partial"
FT /evidence="ECO:0000269|PubMed:15274643"
FT CARBOHYD 60
FT /note="O-linked (GalNAc...) threonine; partial"
FT /evidence="ECO:0000269|PubMed:15274643"
FT CARBOHYD 67
FT /note="O-linked (GalNAc...) threonine; partial"
FT /evidence="ECO:0000269|PubMed:15274643"
FT CARBOHYD 68
FT /note="O-linked (GalNAc...) threonine; partial"
FT /evidence="ECO:0000269|PubMed:15274643"
FT CARBOHYD 73
FT /note="O-linked (GalNAc...) serine; partial"
FT /evidence="ECO:0000269|PubMed:15274643"
FT CARBOHYD 76
FT /note="O-linked (GalNAc...) serine; partial"
FT /evidence="ECO:0000269|PubMed:15274643"
FT CARBOHYD 78
FT /note="O-linked (GalNAc...) threonine; partial"
FT /evidence="ECO:0000269|PubMed:15274643"
FT CARBOHYD 83
FT /note="O-linked (GalNAc...) serine; partial"
FT /evidence="ECO:0000269|PubMed:15274643"
FT NON_TER 1
FT /evidence="ECO:0000303|PubMed:15274643"
FT NON_TER 89
FT /evidence="ECO:0000303|PubMed:15274643"
SQ SEQUENCE 89 AA; 7866 MW; 2D80EF6CA5F5A84D CRC64;
AGSVGRTAGG PGFTSPGRVA GGTGSPTASA RGGTPGGSEG FTAAPGSEST GGHSGAPGTT
LAGRAGTTLG PRSEPSGTGV GGSPVATTL
