ID   MUG1_SCHPO              Reviewed;         351 AA.
AC   Q9USP4;
DT   20-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   25-MAY-2022, entry version 88.
DE   RecName: Full=Meiotically up-regulated gene 1 protein;
GN   Name=mug1; ORFNames=SPCC11E10.03;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   FUNCTION IN MEIOSIS.
RX   PubMed=16303567; DOI=10.1016/j.cub.2005.10.038;
RA   Martin-Castellanos C., Blanco M., Rozalen A.E., Perez-Hidalgo L.,
RA   Garcia A.I., Conde F., Mata J., Ellermeier C., Davis L., San-Segundo P.,
RA   Smith G.R., Moreno S.;
RT   "A large-scale screen in S. pombe identifies seven novel genes required for
RT   critical meiotic events.";
RL   Curr. Biol. 15:2056-2062(2005).
RN   [3]
RP   SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX   PubMed=16823372; DOI=10.1038/nbt1222;
RA   Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA   Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA   Yoshida M.;
RT   "ORFeome cloning and global analysis of protein localization in the fission
RT   yeast Schizosaccharomyces pombe.";
RL   Nat. Biotechnol. 24:841-847(2006).
CC   -!- FUNCTION: Required for correct meiotic chromosome segregation.
CC       {ECO:0000269|PubMed:16303567}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:16823372}.
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DR   EMBL; CU329672; CAB57845.1; -; Genomic_DNA.
DR   PIR; T40854; T40854.
DR   RefSeq; NP_588199.1; NM_001023189.2.
DR   AlphaFoldDB; Q9USP4; -.
DR   SMR; Q9USP4; -.
DR   BioGRID; 275457; 5.
DR   STRING; 4896.SPCC11E10.03.1; -.
DR   PaxDb; Q9USP4; -.
DR   PRIDE; Q9USP4; -.
DR   EnsemblFungi; SPCC11E10.03.1; SPCC11E10.03.1:pep; SPCC11E10.03.
DR   GeneID; 2538878; -.
DR   KEGG; spo:SPCC11E10.03; -.
DR   PomBase; SPCC11E10.03; mug1.
DR   VEuPathDB; FungiDB:SPCC11E10.03; -.
DR   HOGENOM; CLU_790256_0_0_1; -.
DR   InParanoid; Q9USP4; -.
DR   OMA; AETMNRW; -.
DR   PhylomeDB; Q9USP4; -.
DR   PRO; PR:Q9USP4; -.
DR   Proteomes; UP000002485; Chromosome III.
DR   GO; GO:0005737; C:cytoplasm; HDA:PomBase.
DR   GO; GO:0005829; C:cytosol; HDA:PomBase.
DR   GO; GO:0005869; C:dynactin complex; IPI:PomBase.
DR   GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.
DR   GO; GO:0030989; P:dynein-driven meiotic oscillatory nuclear movement; IMP:PomBase.
DR   GO; GO:0007052; P:mitotic spindle organization; IBA:GO_Central.
DR   GO; GO:0098863; P:nuclear migration by microtubule mediated pushing forces; IC:PomBase.
DR   InterPro; IPR028133; Dynamitin.
DR   PANTHER; PTHR15346; PTHR15346; 1.
PE   1: Evidence at protein level;
KW   Chromosome partition; Cytoplasm; Meiosis; Reference proteome.
FT   CHAIN           1..351
FT                   /note="Meiotically up-regulated gene 1 protein"
FT                   /id="PRO_0000278483"
SQ   SEQUENCE   351 AA;  41248 MW;  2CF896460BC53653 CRC64;
     MKEMINLDSS SEPSIVTKQF SVEECLSKLK EQHCYVPMRT IGRLRLRKSS DQTEKKCWKE
     KLMKIRSELE ELWEQSMMYE EQKELTQLGE MLDRLWDKHI NSEGSKSETI SDTAISGNDD
     TMEKRLEQFS DDTLQDTLET EKNLNSKTSE SLKSPTLSYP FDLDSLDKRI FKLESKIGYA
     DEPLSELLNK CMEKLEIVEQ DPQFWQSRIE SWKQLLAKDF LKHHERNLCS IEKQTTLKNS
     SLKELCTEED IVIMLEICSS QLPFVEQYMP ILPLLLERLK SLQNMHTDAA EAISSWQGSK
     DVMMTMQSEL NEWKNTVERL DHSKFYTQSV EEMRRLSDTV TQLEKRVLKL Q