MUG33_SCHPO
ID MUG33_SCHPO Reviewed; 336 AA.
AC O74472;
DT 20-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1998, sequence version 1.
DT 25-MAY-2022, entry version 102.
DE RecName: Full=Meiotically up-regulated gene 33 protein;
GN Name=mug33; ORFNames=SPCC1739.10;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP FUNCTION IN MEIOSIS.
RX PubMed=16303567; DOI=10.1016/j.cub.2005.10.038;
RA Martin-Castellanos C., Blanco M., Rozalen A.E., Perez-Hidalgo L.,
RA Garcia A.I., Conde F., Mata J., Ellermeier C., Davis L., San-Segundo P.,
RA Smith G.R., Moreno S.;
RT "A large-scale screen in S. pombe identifies seven novel genes required for
RT critical meiotic events.";
RL Curr. Biol. 15:2056-2062(2005).
RN [3]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=16823372; DOI=10.1038/nbt1222;
RA Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA Yoshida M.;
RT "ORFeome cloning and global analysis of protein localization in the fission
RT yeast Schizosaccharomyces pombe.";
RL Nat. Biotechnol. 24:841-847(2006).
CC -!- FUNCTION: Has a role in meiosis. {ECO:0000269|PubMed:16303567}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:16823372}.
CC Note=Localizes to the barrier septum and the cell tip.
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DR EMBL; CU329672; CAA20784.1; -; Genomic_DNA.
DR PIR; T41118; T41118.
DR RefSeq; NP_588418.1; NM_001023409.2.
DR AlphaFoldDB; O74472; -.
DR BioGRID; 275947; 47.
DR STRING; 4896.SPCC1739.10.1; -.
DR iPTMnet; O74472; -.
DR MaxQB; O74472; -.
DR PaxDb; O74472; -.
DR PRIDE; O74472; -.
DR EnsemblFungi; SPCC1739.10.1; SPCC1739.10.1:pep; SPCC1739.10.
DR GeneID; 2539381; -.
DR KEGG; spo:SPCC1739.10; -.
DR PomBase; SPCC1739.10; mug33.
DR VEuPathDB; FungiDB:SPCC1739.10; -.
DR eggNOG; ENOG502QVGD; Eukaryota.
DR HOGENOM; CLU_831978_0_0_1; -.
DR InParanoid; O74472; -.
DR OMA; FADYSME; -.
DR PRO; PR:O74472; -.
DR Proteomes; UP000002485; Chromosome III.
DR GO; GO:0032153; C:cell division site; IDA:PomBase.
DR GO; GO:0051286; C:cell tip; HDA:PomBase.
DR GO; GO:0005737; C:cytoplasm; HDA:PomBase.
DR GO; GO:0030139; C:endocytic vesicle; IDA:PomBase.
DR GO; GO:0070382; C:exocytic vesicle; IDA:PomBase.
DR GO; GO:0035838; C:growing cell tip; IMP:PomBase.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0031520; C:plasma membrane of cell tip; IDA:PomBase.
DR GO; GO:0051321; P:meiotic cell cycle; IEA:UniProtKB-KW.
DR InterPro; IPR009571; SUR7/Rim9-like_fungi.
DR Pfam; PF06687; SUR7; 1.
PE 1: Evidence at protein level;
KW Cytoplasm; Meiosis; Reference proteome.
FT CHAIN 1..336
FT /note="Meiotically up-regulated gene 33 protein"
FT /id="PRO_0000278497"
FT REGION 232..336
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 246..262
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 314..329
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 336 AA; 37075 MW; 4021F9B9778166C6 CRC64;
MRIRSATPSL ILLVIAIVFF VLAICTPPLA NNLTLGKYGD VRFGVFGYCL NSNCSKPLVG
YNSDYLDEHA KDGFRTSVIV RQRASYGLVI VPVSACICLI STIMTIFAHI GAIARSPGFF
NVIGTITFFN IFITAIAFVI CVITFVPHIQ WPSWLVLANV GIQLIVLLLL LVARRQATRL
QAKHLRRATS GSLGYNPYSL QNSSNIFSTS SRKGDLPKFS DYSAEKPMYD TISEDDGLKR
GGSVSKLKPT FSNDSRSLSS YAPTVREPVP VPKSNSGFRF PFMRNKPAEQ APENPFRDPE
NPFKDPASAP APNPWSINDV QANNDKKPSR FSWGRS
