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MUG62_SCHPO
ID   MUG62_SCHPO             Reviewed;        1487 AA.
AC   Q09773;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   05-OCT-2016, sequence version 2.
DT   03-AUG-2022, entry version 128.
DE   RecName: Full=Meiotically up-regulated gene 62 protein;
GN   Name=mug62; ORFNames=SPAC22F3.04;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   FUNCTION IN MEIOSIS.
RX   PubMed=16303567; DOI=10.1016/j.cub.2005.10.038;
RA   Martin-Castellanos C., Blanco M., Rozalen A.E., Perez-Hidalgo L.,
RA   Garcia A.I., Conde F., Mata J., Ellermeier C., Davis L., San-Segundo P.,
RA   Smith G.R., Moreno S.;
RT   "A large-scale screen in S. pombe identifies seven novel genes required for
RT   critical meiotic events.";
RL   Curr. Biol. 15:2056-2062(2005).
RN   [3]
RP   SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX   PubMed=16823372; DOI=10.1038/nbt1222;
RA   Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA   Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA   Yoshida M.;
RT   "ORFeome cloning and global analysis of protein localization in the fission
RT   yeast Schizosaccharomyces pombe.";
RL   Nat. Biotechnol. 24:841-847(2006).
RN   [4]
RP   GENE MODEL REVISION.
RX   PubMed=24929437; DOI=10.1038/nsmb.2843;
RA   Duncan C.D., Mata J.;
RT   "The translational landscape of fission-yeast meiosis and sporulation.";
RL   Nat. Struct. Mol. Biol. 21:641-647(2014).
CC   -!- FUNCTION: Has a role in meiosis. {ECO:0000269|PubMed:16303567}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:16823372}.
CC       Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole
CC       body {ECO:0000269|PubMed:16823372}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAA91069.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; CU329670; CAA91069.1; ALT_SEQ; Genomic_DNA.
DR   PIR; T38187; S62419.
DR   RefSeq; NP_593037.1; NM_001018436.2.
DR   AlphaFoldDB; Q09773; -.
DR   SMR; Q09773; -.
DR   BioGRID; 278288; 10.
DR   STRING; 4896.SPAC22F3.04.1; -.
DR   PaxDb; Q09773; -.
DR   PRIDE; Q09773; -.
DR   EnsemblFungi; SPAC22F3.04.1; SPAC22F3.04.1:pep; SPAC22F3.04.
DR   GeneID; 2541797; -.
DR   KEGG; spo:SPAC22F3.04; -.
DR   PomBase; SPAC22F3.04; mug62.
DR   VEuPathDB; FungiDB:SPAC22F3.04; -.
DR   eggNOG; KOG3628; Eukaryota.
DR   HOGENOM; CLU_000737_0_0_1; -.
DR   InParanoid; Q09773; -.
DR   PRO; PR:Q09773; -.
DR   Proteomes; UP000002485; Chromosome I.
DR   GO; GO:0005737; C:cytoplasm; HDA:PomBase.
DR   GO; GO:0005829; C:cytosol; HDA:PomBase.
DR   GO; GO:0005739; C:mitochondrion; ISS:PomBase.
DR   GO; GO:0044732; C:mitotic spindle pole body; HDA:PomBase.
DR   GO; GO:0003824; F:catalytic activity; ISM:PomBase.
DR   GO; GO:0006085; P:acetyl-CoA biosynthetic process; ISS:PomBase.
DR   GO; GO:0051321; P:meiotic cell cycle; IEA:UniProtKB-KW.
DR   CDD; cd05905; Dip2; 2.
DR   Gene3D; 3.30.300.30; -; 1.
DR   Gene3D; 3.40.50.12780; -; 2.
DR   InterPro; IPR045851; AMP-bd_C_sf.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig.
DR   InterPro; IPR042099; ANL_N_sf.
DR   InterPro; IPR037337; Dip2-like_dom.
DR   Pfam; PF00501; AMP-binding; 1.
PE   1: Evidence at protein level;
KW   Cytoplasm; Cytoskeleton; Meiosis; Reference proteome.
FT   CHAIN           1..1487
FT                   /note="Meiotically up-regulated gene 62 protein"
FT                   /id="PRO_0000116399"
SQ   SEQUENCE   1487 AA;  169114 MW;  3292E60480F12D25 CRC64;
     MSLKSFFNFN KKTKLHDIEE DVISEIGSAG SALRTDAHML KANDVYYKSE TDSHTVLRFM
     KPSENEKIHP VRHSKYEDKS KLPFETIPDP VLKYVKRARD AELQPQLAKV SQKLFADIST
     ATAAEKLQFT VPRRARFEIN DPRNPTFSMM ALQDIISVLE YRRNKNPTST AHICIDKKGK
     EAVSYSWDKI LNRAKQFASV AQNHVGLKPG TRVILYYRKS EASEYIISIF GCLLLGIVVI
     PLSPSSSSES LKLVVNEEKV RVAFTTEATY RIFIKDTEVN NAKSLAWWKS NDFTNYKFEQ
     IKQYRMRAND TVLIDYTFSS STYNDIKAVY TTKTFLSQMR NLTSSMITNP ARQAGWKLHN
     FEDSKDVLIT NFHPSMPLGL IMGVFNSVFA GYCTIFCDEE VLKTPGLLAY LITKYRCTYS
     LFDYAGLKQT VYNYQEDPKS TLSFKKNYTP NLSSLKLCMV ECEVVDPEFN IIVSDRWLQP
     LGTNNSKEVI TPILCLRKFG GIPISFKDWM ISYTNRQKHE RQMADTCYQE ILVLKSSIEK
     EKVEIVPFLD IRKYSPNEVL CMSPFWYPIP EASVAVVNED SKNICKVGEV GEIWVYSDCL
     PKLKAASVIN NPQGEQLTDY ENNQENKFEK NNSFMDSGLK GFLHNEKIFV LGNKDEQIRQ
     YRKTMVADKL MEEKYVHYSH YLIKKIMKYV PEIFDGVAFE IEIDKAVYSV LVLESPIIKR
     SLIRNNRLKG RDLFSELVKI TESSFQVTQD IFKLDVLSIL IAPYKSLPRS RYMGIQAINT
     NKCKLAFLSG NLPVSYVRFF MDSALPKSKI NLNNSKGIWS KDASKHHREI ISLNVKQKMD
     PYKHQNKVSK ARENLLNHFT ILDFLKTKSA KTPTSPAILT FNAIEKTKVE LTWAHFELKV
     ASHVEYMQLS VKAKARSHIL LLYYDPLEFL ISIHSCFHLG VIPIPFQIRE ISQLIGEIEE
     FTKIAKAFNV EAILVDHKVL ISLKSRDISN HFQQTCIDLN MKAPKIFETT GIPISKRAKK
     ALNLITPGEL NNKGKVALIS INKLEDGSII PTQFSHSSLL AFCHEQKEFV IGNEEKPIIG
     GIEFSSGMGL LHTALLGVYA GVPTLLIKQE NLCNNGSLLF EAIEQNSLSK VMIPLNICQK
     SFSTAQGCNS IVINSTLSSI IVPCYDRPIS SRVNSIIEDI ARIGLAPNKV KLAYSHPINP
     FVCWNADSSM EKMKDYFDAN QLRSGLVNVR EDVLRNRQPL LYGSGTSTLY NEICIVHPEE
     KYICQEGEIG EIWINGKHGS YCENNELNSG CELLVQETLD KKSYSRTGQL GFIHHLKKKD
     QNMEKVPVLY TLDFIWNTLE LNGLNHSVKD IEETIELVHP NICTDGCILF QASGSVVILL
     EVHSQQKFAS LIPIIVATAL AAHEIILDCV AFVPKGTFLR RPTGEKRRAD ILKQWTGGDL
     KHMTSYLIRQ DFLLNEDFVG TELIGTTDSY DYSDENLIIN SSQLNLL
 
 
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