ID   MUG64_SCHPO             Reviewed;         286 AA.
AC   Q10253;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   22-SEP-2009, sequence version 3.
DT   03-AUG-2022, entry version 108.
DE   RecName: Full=Meiotically up-regulated gene 64 protein;
GN   Name=mug64; ORFNames=SPAC56F8.05c;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   FUNCTION IN MEIOSIS.
RX   PubMed=16303567; DOI=10.1016/j.cub.2005.10.038;
RA   Martin-Castellanos C., Blanco M., Rozalen A.E., Perez-Hidalgo L.,
RA   Garcia A.I., Conde F., Mata J., Ellermeier C., Davis L., San-Segundo P.,
RA   Smith G.R., Moreno S.;
RT   "A large-scale screen in S. pombe identifies seven novel genes required for
RT   critical meiotic events.";
RL   Curr. Biol. 15:2056-2062(2005).
RN   [3]
RP   SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX   PubMed=16823372; DOI=10.1038/nbt1222;
RA   Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA   Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA   Yoshida M.;
RT   "ORFeome cloning and global analysis of protein localization in the fission
RT   yeast Schizosaccharomyces pombe.";
RL   Nat. Biotechnol. 24:841-847(2006).
CC   -!- FUNCTION: Has a role in meiosis. {ECO:0000269|PubMed:16303567}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:16823372}.
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DR   EMBL; CU329670; CAA93576.3; -; Genomic_DNA.
DR   PIR; T38915; T38915.
DR   RefSeq; NP_593220.2; NM_001018616.3.
DR   AlphaFoldDB; Q10253; -.
DR   BioGRID; 279657; 12.
DR   IntAct; Q10253; 1.
DR   MINT; Q10253; -.
DR   STRING; 4896.SPAC56F8.05c.1; -.
DR   iPTMnet; Q10253; -.
DR   MaxQB; Q10253; -.
DR   PaxDb; Q10253; -.
DR   PRIDE; Q10253; -.
DR   EnsemblFungi; SPAC56F8.05c.1; SPAC56F8.05c.1:pep; SPAC56F8.05c.
DR   GeneID; 2543229; -.
DR   KEGG; spo:SPAC56F8.05c; -.
DR   PomBase; SPAC56F8.05c; mug64.
DR   VEuPathDB; FungiDB:SPAC56F8.05c; -.
DR   eggNOG; ENOG502QQ2V; Eukaryota.
DR   HOGENOM; CLU_059017_0_0_1; -.
DR   InParanoid; Q10253; -.
DR   OMA; SYDYPKE; -.
DR   PhylomeDB; Q10253; -.
DR   PRO; PR:Q10253; -.
DR   Proteomes; UP000002485; Chromosome I.
DR   GO; GO:0005737; C:cytoplasm; HDA:PomBase.
DR   GO; GO:0030173; C:integral component of Golgi membrane; ISO:PomBase.
DR   GO; GO:0006897; P:endocytosis; ISO:PomBase.
DR   GO; GO:0051321; P:meiotic cell cycle; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.1270.60; -; 1.
DR   InterPro; IPR027267; AH/BAR_dom_sf.
DR   InterPro; IPR018859; BAR_dom-cont.
DR   Pfam; PF10455; BAR_2; 1.
DR   SUPFAM; SSF103657; SSF103657; 1.
PE   1: Evidence at protein level;
KW   Cytoplasm; Meiosis; Reference proteome.
FT   CHAIN           1..286
FT                   /note="Meiotically up-regulated gene 64 protein"
FT                   /id="PRO_0000116567"
SQ   SEQUENCE   286 AA;  31748 MW;  2EC915AC7CED234B CRC64;
     METFKTHITG QFNATVSSIT PFAKKTTHYL RTKIGSRVEE LSLPEDYVEL EQQVDSLKEA
     YNLVLPIVET VEVDGYDYPT NFRDSITDFG KTVSGKVRNL GNLTPLEQTP LASVGKNLEE
     KEAAAKPSRT LYNAISRAAS EATTKMGAGN PLSSAFGQIS VLEEKVGNLQ GERDSAISKN
     FCEQVRAVLY PRFAEAHRVK ADVQDKRLQL EMAKLDVESA KPENLEHCKS AVRSAEDELN
     GAIEHAKILY EQILNKDYNT DLLRSIIKNQ LKFHQDAAAA LSDITI