ID   MUG68_SCHPO             Reviewed;         515 AA.
AC   Q10310;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   25-MAY-2022, entry version 81.
DE   RecName: Full=Meiotically up-regulated gene 68 protein;
GN   Name=mug68; ORFNames=SPAC6C3.07;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   FUNCTION IN MEIOSIS.
RX   PubMed=16303567; DOI=10.1016/j.cub.2005.10.038;
RA   Martin-Castellanos C., Blanco M., Rozalen A.E., Perez-Hidalgo L.,
RA   Garcia A.I., Conde F., Mata J., Ellermeier C., Davis L., San-Segundo P.,
RA   Smith G.R., Moreno S.;
RT   "A large-scale screen in S. pombe identifies seven novel genes required for
RT   critical meiotic events.";
RL   Curr. Biol. 15:2056-2062(2005).
CC   -!- FUNCTION: Has a role in meiosis. {ECO:0000269|PubMed:16303567}.
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DR   EMBL; CU329670; CAA93619.1; -; Genomic_DNA.
DR   PIR; T39031; T39031.
DR   RefSeq; NP_593721.1; NM_001019152.2.
DR   AlphaFoldDB; Q10310; -.
DR   SMR; Q10310; -.
DR   BioGRID; 279394; 1.
DR   STRING; 4896.SPAC6C3.07.1; -.
DR   iPTMnet; Q10310; -.
DR   PaxDb; Q10310; -.
DR   EnsemblFungi; SPAC6C3.07.1; SPAC6C3.07.1:pep; SPAC6C3.07.
DR   GeneID; 2542954; -.
DR   KEGG; spo:SPAC6C3.07; -.
DR   PomBase; SPAC6C3.07; mug68.
DR   VEuPathDB; FungiDB:SPAC6C3.07; -.
DR   HOGENOM; CLU_529090_0_0_1; -.
DR   PRO; PR:Q10310; -.
DR   Proteomes; UP000002485; Chromosome I.
DR   GO; GO:0051321; P:meiotic cell cycle; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Meiosis; Reference proteome.
FT   CHAIN           1..515
FT                   /note="Meiotically up-regulated gene 68 protein"
FT                   /id="PRO_0000116587"
FT   REGION          165..204
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        176..193
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   515 AA;  59035 MW;  B0466464840B3F06 CRC64;
     MNTRNMFDIL RKGIFKDEIT QIEKILLKME DNTYEYVDVF LEKYESQQKL LLKLTKAITE
     YLSNLKPQLS KQENIYVKHI KSSNEAKTEL EIFNCYKEIS ISKEKKINSL LKLVRESAQD
     YTINEENDIL YHSEISAKKN ASPMEFGDAS FDLEKQRLHF ANSNLHSIES ERNESSLSLD
     SGESEKKSEE DNGNGEQNYI PEQYERLDSP VKEKIINTCC KGKAEPPNYE RIKPKAKKGN
     QMQKIKISKL GTAETQTEDV MNKSSQKENN DILRKHKTSV KFPTNLDALN SCTMENHEIN
     ELTATNKMND GPITKCARET INIKNLKTSN LERNQNSPKN KRTVSYERLA NSFSFNALND
     YNLKKGGEKL RKKAIKRALK DRGSQDKAYG GVVQSNSRQP KVGFHVNNSS SGHNDNEGNH
     SLILSSKTKS PQLFNNEKKD ESYSGFSNTN SYAIEETSRA LMGTSKTRKP ENKSKYLIKN
     GWFEDSLNSE IWSDANPLDW RKTDILEEST SIVYK