位置:首页 > 蛋白库 > MUG72_SCHPO
MUG72_SCHPO
ID   MUG72_SCHPO             Reviewed;         574 AA.
AC   Q9Y7P6; Q9UTU8;
DT   29-MAR-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1999, sequence version 1.
DT   25-MAY-2022, entry version 117.
DE   RecName: Full=Meiotically up-regulated gene 72 protein;
GN   Name=mug72; ORFNames=SPCC1902.02, SPCC663.16c;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] OF 357-536, AND SUBCELLULAR
RP   LOCATION.
RC   STRAIN=ATCC 38364 / 968;
RX   PubMed=10759889; DOI=10.1046/j.1365-2443.2000.00317.x;
RA   Ding D.-Q., Tomita Y., Yamamoto A., Chikashige Y., Haraguchi T.,
RA   Hiraoka Y.;
RT   "Large-scale screening of intracellular protein localization in living
RT   fission yeast cells by the use of a GFP-fusion genomic DNA library.";
RL   Genes Cells 5:169-190(2000).
RN   [3]
RP   FUNCTION IN MEIOSIS.
RX   PubMed=16303567; DOI=10.1016/j.cub.2005.10.038;
RA   Martin-Castellanos C., Blanco M., Rozalen A.E., Perez-Hidalgo L.,
RA   Garcia A.I., Conde F., Mata J., Ellermeier C., Davis L., San-Segundo P.,
RA   Smith G.R., Moreno S.;
RT   "A large-scale screen in S. pombe identifies seven novel genes required for
RT   critical meiotic events.";
RL   Curr. Biol. 15:2056-2062(2005).
RN   [4]
RP   SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX   PubMed=16823372; DOI=10.1038/nbt1222;
RA   Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA   Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA   Yoshida M.;
RT   "ORFeome cloning and global analysis of protein localization in the fission
RT   yeast Schizosaccharomyces pombe.";
RL   Nat. Biotechnol. 24:841-847(2006).
RN   [5]
RP   PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-343 AND SER-392, AND
RP   IDENTIFICATION BY MASS SPECTROMETRY.
RX   PubMed=18257517; DOI=10.1021/pr7006335;
RA   Wilson-Grady J.T., Villen J., Gygi S.P.;
RT   "Phosphoproteome analysis of fission yeast.";
RL   J. Proteome Res. 7:1088-1097(2008).
CC   -!- FUNCTION: Has a role in meiosis. {ECO:0000269|PubMed:16303567}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:10759889,
CC       ECO:0000269|PubMed:16823372}. Note=Localizes at the cell tip and
CC       barrier septum.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CU329672; CAB40004.1; -; Genomic_DNA.
DR   EMBL; AB027984; BAA87288.1; -; Genomic_DNA.
DR   PIR; T41207; T41207.
DR   RefSeq; NP_588277.1; NM_001023267.3.
DR   AlphaFoldDB; Q9Y7P6; -.
DR   SMR; Q9Y7P6; -.
DR   BioGRID; 275899; 8.
DR   STRING; 4896.SPCC1902.02.1; -.
DR   iPTMnet; Q9Y7P6; -.
DR   MaxQB; Q9Y7P6; -.
DR   PaxDb; Q9Y7P6; -.
DR   PRIDE; Q9Y7P6; -.
DR   EnsemblFungi; SPCC1902.02.1; SPCC1902.02.1:pep; SPCC1902.02.
DR   GeneID; 2539333; -.
DR   KEGG; spo:SPCC1902.02; -.
DR   PomBase; SPCC1902.02; mug72.
DR   VEuPathDB; FungiDB:SPCC1902.02; -.
DR   eggNOG; ENOG502QT3Z; Eukaryota.
DR   HOGENOM; CLU_471855_0_0_1; -.
DR   InParanoid; Q9Y7P6; -.
DR   OMA; VQDAMIE; -.
DR   PhylomeDB; Q9Y7P6; -.
DR   PRO; PR:Q9Y7P6; -.
DR   Proteomes; UP000002485; Chromosome III.
DR   GO; GO:0032153; C:cell division site; HDA:PomBase.
DR   GO; GO:0051286; C:cell tip; HDA:PomBase.
DR   GO; GO:0005737; C:cytoplasm; HDA:PomBase.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0051321; P:meiotic cell cycle; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.1040.10; -; 1.
DR   InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR   InterPro; IPR013328; 6PGD_dom2.
DR   InterPro; IPR013752; KPA_reductase.
DR   InterPro; IPR013332; KPR_N.
DR   Pfam; PF02558; ApbA; 1.
DR   Pfam; PF08546; ApbA_C; 1.
DR   SUPFAM; SSF48179; SSF48179; 1.
PE   1: Evidence at protein level;
KW   Cytoplasm; Meiosis; Phosphoprotein; Reference proteome.
FT   CHAIN           1..574
FT                   /note="Meiotically up-regulated gene 72 protein"
FT                   /id="PRO_0000116550"
FT   REGION          339..374
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          422..451
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          495..574
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        339..353
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        495..509
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        542..563
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         343
FT                   /note="Phosphothreonine"
FT                   /evidence="ECO:0000269|PubMed:18257517"
FT   MOD_RES         392
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000269|PubMed:18257517"
FT   CONFLICT        358..364
FT                   /note="PVGAASR -> SGCLPHG (in Ref. 2)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   574 AA;  62847 MW;  6A4D8DF5F4858F92 CRC64;
     MSEEDTSKLR ILSVGSNAIS AFISWRLSES KACHTTLIWR NRCESVLSEG IRIRSSVFGS
     TKWKPDVVAP TVEQLAMNSE PFDYIFVCLK ILPSVYNLDT AIKEVVTPGH TCIVLNTTGI
     VGAEKELQHA FPNNPVLSFV LPDQFAQRGP LQFEHTTFAA DSAKSVIYVG LTEEEDDVPD
     SVQDAMIETL TLTLEAGGVS CDFLSKIQKK QWETGVGHMC FYPLSIINDE PNLALMYRLK
     SFAKVIDGLM DEAFSIAQAQ GCEFEPEKLD VLKRHIVNRM LATPRPSYPY QDYIAHRPLE
     VAVLLGYPVE IAKELGVSVP RMETLLALFD AKNKRNLTVR AGTPQSSPNF NPAMRRSPVG
     AASRSPSRST IGISNRIGSV DDLLNTRQFT SSPIGGSMPK GPNSIYKIPS ASMVNLSSPL
     VTSPSGLNPT GRPSRFGGRV RGNPLTMNKA GSVSDLLSTS TNMASSDALE TASMIGVPSA
     MPPNSFDMLT LTQRRNRRNN QSSSPPAPSD RRYTMGARRP VQTRGMTDSV IPILEDPMST
     LYDTSRYPTR NSKPATPKAS RPPSIASTVH RRMD
 
 
维奥蛋白资源库 - 中文蛋白资源 CopyRight © 2010-2024