MUG73_SCHPO
ID MUG73_SCHPO Reviewed; 306 AA.
AC O74870;
DT 20-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1998, sequence version 1.
DT 25-MAY-2022, entry version 111.
DE RecName: Full=Meiotically up-regulated gene 73 protein;
GN Name=mug73; ORFNames=SPCC31H12.02c;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP FUNCTION IN MEIOSIS.
RX PubMed=16303567; DOI=10.1016/j.cub.2005.10.038;
RA Martin-Castellanos C., Blanco M., Rozalen A.E., Perez-Hidalgo L.,
RA Garcia A.I., Conde F., Mata J., Ellermeier C., Davis L., San-Segundo P.,
RA Smith G.R., Moreno S.;
RT "A large-scale screen in S. pombe identifies seven novel genes required for
RT critical meiotic events.";
RL Curr. Biol. 15:2056-2062(2005).
CC -!- FUNCTION: Has a role in meiosis. {ECO:0000269|PubMed:16303567}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the archaeal/bacterial/fungal opsin family.
CC {ECO:0000305}.
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DR EMBL; CU329672; CAA21219.1; -; Genomic_DNA.
DR PIR; T41290; T41290.
DR RefSeq; NP_587895.1; NM_001022887.2.
DR AlphaFoldDB; O74870; -.
DR SMR; O74870; -.
DR BioGRID; 275314; 39.
DR STRING; 4896.SPCC31H12.02c.1; -.
DR iPTMnet; O74870; -.
DR SwissPalm; O74870; -.
DR PaxDb; O74870; -.
DR EnsemblFungi; SPCC31H12.02c.1; SPCC31H12.02c.1:pep; SPCC31H12.02c.
DR GeneID; 2538730; -.
DR KEGG; spo:SPCC31H12.02c; -.
DR PomBase; SPCC31H12.02c; mug73.
DR VEuPathDB; FungiDB:SPCC31H12.02c; -.
DR eggNOG; ENOG502RWTP; Eukaryota.
DR HOGENOM; CLU_054785_4_0_1; -.
DR InParanoid; O74870; -.
DR OMA; IFHYITA; -.
DR PhylomeDB; O74870; -.
DR PRO; PR:O74870; -.
DR Proteomes; UP000002485; Chromosome III.
DR GO; GO:0016021; C:integral component of membrane; ISO:PomBase.
DR GO; GO:0005886; C:plasma membrane; ISO:PomBase.
DR GO; GO:0051321; P:meiotic cell cycle; IEA:UniProtKB-KW.
DR CDD; cd15239; 7tm_YRO2_fungal-like; 1.
DR InterPro; IPR001425; Arc/bac/fun_rhodopsins.
DR InterPro; IPR043476; Yro2-like_7TM.
DR PANTHER; PTHR28286; PTHR28286; 1.
DR Pfam; PF01036; Bac_rhodopsin; 1.
DR PRINTS; PR00251; BACTRLOPSIN.
DR SMART; SM01021; Bac_rhodopsin; 1.
PE 1: Evidence at protein level;
KW Meiosis; Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT CHAIN 1..306
FT /note="Meiotically up-regulated gene 73 protein"
FT /id="PRO_0000278563"
FT TRANSMEM 28..48
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 59..79
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 103..123
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 125..145
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 154..174
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 190..210
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 224..244
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 306 AA; 34664 MW; 5C18E637628DF080 CRC64;
MNAKLSSSGM VLKELPEVAL QKISSNYYWA VFAVFLLCAI VFPLVSIFSL PQKQTYHRFF
SILSLVSCLA YFTMACNYGL KNVFSSASFF REVSVRMVYY VRYIQWLINF PLIIVMLHWT
VGVSILEIAY VVCYVLFAIV CLLAAALTSS PYKWAYYGFS FVGYFIALAH SVVLHKKYAS
RLETSARLGF LWSIVYLHVI WFLYYACWIL SEGLNVISPI GEAIFYSILD LFEFGFFGAA
FSWMLDLVGI ENFKSPQSIP LGACSPADDK FSMCPDMEAQ NQADDLAVET RIQISNLPSS
PTKNNC
