ID   MUG87_SCHPO             Reviewed;         851 AA.
AC   O94418;
DT   20-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1999, sequence version 1.
DT   03-AUG-2022, entry version 114.
DE   RecName: Full=Meiotically up-regulated gene 87 protein;
GN   Name=mug87; ORFNames=SPCC1620.11;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   FUNCTION IN MEIOSIS.
RX   PubMed=16303567; DOI=10.1016/j.cub.2005.10.038;
RA   Martin-Castellanos C., Blanco M., Rozalen A.E., Perez-Hidalgo L.,
RA   Garcia A.I., Conde F., Mata J., Ellermeier C., Davis L., San-Segundo P.,
RA   Smith G.R., Moreno S.;
RT   "A large-scale screen in S. pombe identifies seven novel genes required for
RT   critical meiotic events.";
RL   Curr. Biol. 15:2056-2062(2005).
RN   [3]
RP   SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX   PubMed=16823372; DOI=10.1038/nbt1222;
RA   Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA   Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA   Yoshida M.;
RT   "ORFeome cloning and global analysis of protein localization in the fission
RT   yeast Schizosaccharomyces pombe.";
RL   Nat. Biotechnol. 24:841-847(2006).
CC   -!- FUNCTION: Has a role in meiosis. {ECO:0000269|PubMed:16303567}.
CC   -!- SUBCELLULAR LOCATION: Nucleus envelope {ECO:0000269|PubMed:16823372}.
CC   -!- SIMILARITY: Belongs to the nucleoporin interacting component (NIC)
CC       family. {ECO:0000305}.
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DR   EMBL; CU329672; CAA22495.1; -; Genomic_DNA.
DR   PIR; T41041; T41041.
DR   RefSeq; NP_588469.1; NM_001023460.2.
DR   AlphaFoldDB; O94418; -.
DR   SMR; O94418; -.
DR   BioGRID; 275441; 35.
DR   STRING; 4896.SPCC1620.11.1; -.
DR   iPTMnet; O94418; -.
DR   MaxQB; O94418; -.
DR   PaxDb; O94418; -.
DR   PRIDE; O94418; -.
DR   EnsemblFungi; SPCC1620.11.1; SPCC1620.11.1:pep; SPCC1620.11.
DR   GeneID; 2538861; -.
DR   KEGG; spo:SPCC1620.11; -.
DR   PomBase; SPCC1620.11; -.
DR   VEuPathDB; FungiDB:SPCC1620.11; -.
DR   eggNOG; KOG2168; Eukaryota.
DR   HOGENOM; CLU_011846_0_0_1; -.
DR   InParanoid; O94418; -.
DR   OMA; NMAATMP; -.
DR   PhylomeDB; O94418; -.
DR   Reactome; R-SPO-159227; Transport of the SLBP independent Mature mRNA.
DR   Reactome; R-SPO-159231; Transport of Mature mRNA Derived from an Intronless Transcript.
DR   Reactome; R-SPO-159236; Transport of Mature mRNA derived from an Intron-Containing Transcript.
DR   Reactome; R-SPO-3232142; SUMOylation of ubiquitinylation proteins.
DR   Reactome; R-SPO-4085377; SUMOylation of SUMOylation proteins.
DR   Reactome; R-SPO-4551638; SUMOylation of chromatin organization proteins.
DR   Reactome; R-SPO-4570464; SUMOylation of RNA binding proteins.
DR   Reactome; R-SPO-5578749; Transcriptional regulation by small RNAs.
DR   Reactome; R-SPO-9615933; Postmitotic nuclear pore complex (NPC) reformation.
DR   PRO; PR:O94418; -.
DR   Proteomes; UP000002485; Chromosome III.
DR   GO; GO:0005829; C:cytosol; HDA:PomBase.
DR   GO; GO:0005635; C:nuclear envelope; HDA:PomBase.
DR   GO; GO:0005643; C:nuclear pore; IDA:PomBase.
DR   GO; GO:0017056; F:structural constituent of nuclear pore; IBA:GO_Central.
DR   GO; GO:0051321; P:meiotic cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0016973; P:poly(A)+ mRNA export from nucleus; IMP:PomBase.
DR   GO; GO:0006606; P:protein import into nucleus; IBA:GO_Central.
DR   InterPro; IPR007231; Nucleoporin_int_Nup93/Nic96.
DR   PANTHER; PTHR11225; PTHR11225; 1.
DR   Pfam; PF04097; Nic96; 1.
PE   1: Evidence at protein level;
KW   Meiosis; Nucleus; Reference proteome.
FT   CHAIN           1..851
FT                   /note="Meiotically up-regulated gene 87 protein"
FT                   /id="PRO_0000278569"
SQ   SEQUENCE   851 AA;  97564 MW;  EC5D52D1CD4F3D16 CRC64;
     MTVASDDSPK EARGIPFLDQ KSRKLANELL EPCLPFIQFN LGEIEQRAKH YLNTVPTSKD
     GNTKAHYLLA GSGINAEQTW KKIESLSLQV RPPTTLELSF TDVDMFLKYH REKNVLNSLE
     ALVQNTQIAF DQYLEEEWRS KAAKSRPSFD NILLENKKRV SFYPFSVQRS QKFASTLKMC
     LEEEALHGFQ SKLVSSFCEV AREFAHDTKS LLLYESWKLL SSVILDKDSV TVFGNKGIIS
     KAFDIETEDG SVNSRFYQRI SDCSRKFLEA QFFEVLNKEI AKTPQAALVG GVPSIRNKIR
     AYLNIRLLRN GVWINPDLEI IQDVPIWAFI FYLLRCGFLK EAVDFTEENR DLFEKVAEKF
     PFYINAYAKA PNGILPRQLR SQLFSEFNQT IRLQESSDPY KYAVYKIIGR CDLSKTSCPS
     ICSVTEDYIW FQLILSREFT EKSVSAHEFF SLEDVQHILL SYGSDYFTNN GSNPVMYFFL
     LMLCGLYERA INFLYPYFPT DAVHFAITCA YYGLLRTAPS SSVVSNEPGK IQSMLVETKS
     GKPSLEFDRL LIDYTQTCQE LSPVMSACYL IPMCKIDKYI SMCHKSLCSL VLSTRDYVNL
     LGDIRGDGER TPSFLENHRS LIGLSSVKEY LSKITLTAAK QADDQGLLSD AILLYHLAED
     YDAAVTVINR RLGSALLRFL DQFVFPDKLI SLTKSMMDVY NRNPSLYAKV DYKNRETTNL
     LLLTVEAFNA YTNKDYEQAL SSLQQLEILP LDPLDSDCET FVVRKLAKEF RFLNENLLQN
     VPGIVLIAMN SLKELYAKQK SSSFGNDAIS VDKLRLYRQK ARRIVMYSFL IEYRMPSQIL
     EQLNRCEIEM T