ID   MUG97_SCHPO             Reviewed;         345 AA.
AC   Q9Y800; Q3LFP6;
DT   19-JUL-2004, integrated into UniProtKB/Swiss-Prot.
DT   11-JUL-2012, sequence version 2.
DT   25-MAY-2022, entry version 90.
DE   RecName: Full=Meiotically up-regulated gene 97 protein;
DE   AltName: Full=Meiotic expression up-regulated protein 33;
GN   Name=mug97; Synonyms=meu33; ORFNames=SPBC146.11c;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Saito T.T., Nojima H.;
RT   "Meiotic expression upregulated.";
RL   Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [3]
RP   REVISION OF GENE MODEL.
RX   PubMed=21511999; DOI=10.1126/science.1203357;
RA   Rhind N., Chen Z., Yassour M., Thompson D.A., Haas B.J., Habib N.,
RA   Wapinski I., Roy S., Lin M.F., Heiman D.I., Young S.K., Furuya K., Guo Y.,
RA   Pidoux A., Chen H.M., Robbertse B., Goldberg J.M., Aoki K., Bayne E.H.,
RA   Berlin A.M., Desjardins C.A., Dobbs E., Dukaj L., Fan L., FitzGerald M.G.,
RA   French C., Gujja S., Hansen K., Keifenheim D., Levin J.Z., Mosher R.A.,
RA   Mueller C.A., Pfiffner J., Priest M., Russ C., Smialowska A., Swoboda P.,
RA   Sykes S.M., Vaughn M., Vengrova S., Yoder R., Zeng Q., Allshire R.,
RA   Baulcombe D., Birren B.W., Brown W., Ekwall K., Kellis M., Leatherwood J.,
RA   Levin H., Margalit H., Martienssen R., Nieduszynski C.A., Spatafora J.W.,
RA   Friedman N., Dalgaard J.Z., Baumann P., Niki H., Regev A., Nusbaum C.;
RT   "Comparative functional genomics of the fission yeasts.";
RL   Science 332:930-936(2011).
RN   [4]
RP   FUNCTION IN MEIOSIS/SPORULATION.
RX   PubMed=16303567; DOI=10.1016/j.cub.2005.10.038;
RA   Martin-Castellanos C., Blanco M., Rozalen A.E., Perez-Hidalgo L.,
RA   Garcia A.I., Conde F., Mata J., Ellermeier C., Davis L., San-Segundo P.,
RA   Smith G.R., Moreno S.;
RT   "A large-scale screen in S. pombe identifies seven novel genes required for
RT   critical meiotic events.";
RL   Curr. Biol. 15:2056-2062(2005).
CC   -!- FUNCTION: Required for correct meiotic chromosome segregation. Appears
CC       to also have role in sporulation. {ECO:0000269|PubMed:16303567}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAE46409.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; AB237169; BAE46409.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; CU329671; CAB46764.2; -; Genomic_DNA.
DR   PIR; T39425; T39425.
DR   RefSeq; NP_595400.2; NM_001021307.2.
DR   AlphaFoldDB; Q9Y800; -.
DR   BioGRID; 276689; 2.
DR   STRING; 4896.SPBC146.11c.1; -.
DR   PaxDb; Q9Y800; -.
DR   PRIDE; Q9Y800; -.
DR   EnsemblFungi; SPBC146.11c.1; SPBC146.11c.1:pep; SPBC146.11c.
DR   GeneID; 2540153; -.
DR   KEGG; spo:SPBC146.11c; -.
DR   PomBase; SPBC146.11c; mug97.
DR   VEuPathDB; FungiDB:SPBC146.11c; -.
DR   HOGENOM; CLU_804503_0_0_1; -.
DR   PRO; PR:Q9Y800; -.
DR   Proteomes; UP000002485; Chromosome II.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.
DR   GO; GO:0051321; P:meiotic cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Chromosome partition; Meiosis; Membrane; Reference proteome; Sporulation;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..345
FT                   /note="Meiotically up-regulated gene 97 protein"
FT                   /id="PRO_0000116850"
FT   TRANSMEM        292..312
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        319..329
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   345 AA;  39385 MW;  B74AAFBA1CA31CD0 CRC64;
     MSILNSGSCM MTDTNQNMEC KVDFKKGEFD LQPLQINQFG FTKTQLHKPL TRNLSNKEDT
     HVPKRQKVSE PYFRGETERN VKSHQDRAAS IYHEAMNGAS GIHKQMSLPE YSPQMGNSWE
     IQVPMTTRHS ISETPTKPFT ATTAIAGSAG SLPRNTTIGL PGPSALLKHE SGKNENQVRV
     CLYHKHYSRW YLPFDKDDDN QLVEAYAKYF SSENRPSIFY VLQGISFGPE CEYVLRRKHW
     WNPWAEKVMR REIVERKIDT HPGCRTVAER YEQIEASGSE ELLIIPIYKI NMWVLSLLLF
     SAGGSVLIGL WMRLSDPSFA HGMLLNLGIG SIGSFLYLLS NTWCR