MUKE_ALISL
ID MUKE_ALISL Reviewed; 238 AA.
AC B6ERZ8;
DT 28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT 25-NOV-2008, sequence version 1.
DT 25-MAY-2022, entry version 54.
DE RecName: Full=Chromosome partition protein MukE {ECO:0000255|HAMAP-Rule:MF_01802};
GN Name=mukE {ECO:0000255|HAMAP-Rule:MF_01802}; OrderedLocusNames=VSAL_II0728;
OS Aliivibrio salmonicida (strain LFI1238) (Vibrio salmonicida (strain
OS LFI1238)).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Aliivibrio.
OX NCBI_TaxID=316275;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LFI1238;
RX PubMed=19099551; DOI=10.1186/1471-2164-9-616;
RA Hjerde E., Lorentzen M.S., Holden M.T., Seeger K., Paulsen S., Bason N.,
RA Churcher C., Harris D., Norbertczak H., Quail M.A., Sanders S.,
RA Thurston S., Parkhill J., Willassen N.P., Thomson N.R.;
RT "The genome sequence of the fish pathogen Aliivibrio salmonicida strain
RT LFI1238 shows extensive evidence of gene decay.";
RL BMC Genomics 9:616-616(2008).
CC -!- FUNCTION: Involved in chromosome condensation, segregation and cell
CC cycle progression. May participate in facilitating chromosome
CC segregation by condensation DNA from both sides of a centrally located
CC replisome during cell division. Probably acts via its interaction with
CC MukB and MukF. {ECO:0000255|HAMAP-Rule:MF_01802}.
CC -!- SUBUNIT: Interacts, and probably forms a ternary complex, with MukF and
CC MukB. The complex formation is stimulated by calcium or magnesium.
CC {ECO:0000255|HAMAP-Rule:MF_01802}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, nucleoid {ECO:0000255|HAMAP-
CC Rule:MF_01802}. Note=Restricted to the nucleoid region.
CC {ECO:0000255|HAMAP-Rule:MF_01802}.
CC -!- SIMILARITY: Belongs to the MukE family. {ECO:0000255|HAMAP-
CC Rule:MF_01802}.
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DR EMBL; FM178380; CAQ81482.1; -; Genomic_DNA.
DR AlphaFoldDB; B6ERZ8; -.
DR SMR; B6ERZ8; -.
DR STRING; 316275.VSAL_II0728; -.
DR EnsemblBacteria; CAQ81482; CAQ81482; VSAL_II0728.
DR KEGG; vsa:VSAL_II0728; -.
DR eggNOG; COG3095; Bacteria.
DR HOGENOM; CLU_1146408_0_0_6; -.
DR OMA; FLMDYQE; -.
DR Proteomes; UP000001730; Chromosome 2.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-UniRule.
DR GO; GO:0009295; C:nucleoid; IEA:UniProtKB-SubCell.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0030261; P:chromosome condensation; IEA:UniProtKB-KW.
DR GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-UniRule.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.10.2250; -; 1.
DR Gene3D; 1.10.10.2260; -; 1.
DR HAMAP; MF_01802; MukE; 1.
DR InterPro; IPR042037; MukE_C.
DR InterPro; IPR042038; MukE_N.
DR InterPro; IPR007385; Scp_MukE.
DR Pfam; PF04288; MukE; 1.
PE 3: Inferred from homology;
KW Cell cycle; Cell division; Chromosome partition; Cytoplasm;
KW DNA condensation.
FT CHAIN 1..238
FT /note="Chromosome partition protein MukE"
FT /id="PRO_1000187495"
FT REGION 206..238
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 210..231
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 238 AA; 27082 MW; 09CCC025B80463C9 CRC64;
MPEKLAKAIA NPLFPALDSL LRSGRHIASE DLDNHALLCE FEHELGMFYQ RYHAELVKAP
EGFFYLRPRS TSLIARSVLA EVDMLVGKVL CFLYLSPERL AHEGIFTNQE LFDELLVLAD
EQKLMKLVTN RASGSDLDKE KLFDKVRTSL RRLKRLGMII QVGEQGKFRI SEAVFRFGAD
VRSNDDMKEA QLRLIRDGEA VVVHNEESSQ SSFDLDENEK LSDISAEEQH ELELEGDA
