ID   MUKE_HAEDU              Reviewed;         238 AA.
AC   Q7VL95;
DT   16-JAN-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2003, sequence version 1.
DT   25-MAY-2022, entry version 89.
DE   RecName: Full=Chromosome partition protein MukE {ECO:0000255|HAMAP-Rule:MF_01802};
GN   Name=mukE {ECO:0000255|HAMAP-Rule:MF_01802}; OrderedLocusNames=HD_1584;
OS   Haemophilus ducreyi (strain 35000HP / ATCC 700724).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=233412;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=35000HP / ATCC 700724;
RA   Munson R.S. Jr., Ray W.C., Mahairas G., Sabo P., Mungur R., Johnson L.,
RA   Nguyen D., Wang J., Forst C., Hood L.;
RT   "The complete genome sequence of Haemophilus ducreyi.";
RL   Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Involved in chromosome condensation, segregation and cell
CC       cycle progression. May participate in facilitating chromosome
CC       segregation by condensation DNA from both sides of a centrally located
CC       replisome during cell division. Probably acts via its interaction with
CC       MukB and MukF. {ECO:0000255|HAMAP-Rule:MF_01802}.
CC   -!- SUBUNIT: Interacts, and probably forms a ternary complex, with MukF and
CC       MukB. The complex formation is stimulated by calcium or magnesium.
CC       {ECO:0000255|HAMAP-Rule:MF_01802}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, nucleoid {ECO:0000255|HAMAP-
CC       Rule:MF_01802}. Note=Restricted to the nucleoid region.
CC       {ECO:0000255|HAMAP-Rule:MF_01802}.
CC   -!- SIMILARITY: Belongs to the MukE family. {ECO:0000255|HAMAP-
CC       Rule:MF_01802}.
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DR   EMBL; AE017143; AAP96364.1; -; Genomic_DNA.
DR   RefSeq; WP_010945396.1; NC_002940.2.
DR   PDB; 3EUK; X-ray; 4.00 A; L/M=1-238.
DR   PDBsum; 3EUK; -.
DR   AlphaFoldDB; Q7VL95; -.
DR   SMR; Q7VL95; -.
DR   IntAct; Q7VL95; 2.
DR   STRING; 233412.HD_1584; -.
DR   EnsemblBacteria; AAP96364; AAP96364; HD_1584.
DR   KEGG; hdu:HD_1584; -.
DR   eggNOG; COG3095; Bacteria.
DR   HOGENOM; CLU_1146408_0_0_6; -.
DR   OMA; FLMDYQE; -.
DR   EvolutionaryTrace; Q7VL95; -.
DR   Proteomes; UP000001022; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-UniRule.
DR   GO; GO:0009295; C:nucleoid; IEA:UniProtKB-SubCell.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0030261; P:chromosome condensation; IEA:UniProtKB-KW.
DR   GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.10.2250; -; 1.
DR   Gene3D; 1.10.10.2260; -; 1.
DR   HAMAP; MF_01802; MukE; 1.
DR   InterPro; IPR042037; MukE_C.
DR   InterPro; IPR042038; MukE_N.
DR   InterPro; IPR007385; Scp_MukE.
DR   Pfam; PF04288; MukE; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Cell cycle; Cell division; Chromosome partition; Cytoplasm;
KW   DNA condensation; Reference proteome.
FT   CHAIN           1..238
FT                   /note="Chromosome partition protein MukE"
FT                   /id="PRO_0000206796"
SQ   SEQUENCE   238 AA;  26842 MW;  F4D5D59D0A9C1FEC CRC64;
     MTEYIQDAIP AKLAIAIANP IFPQLDSQLR AGRHISIEML DEHAFLMDFQ TELESFYRRY
     HVDLIRAPEG FFYLRPKAST LIARSAMSEM EMLVGKVLCY LYLSPERLAQ QGIFSQDDVY
     EELLNLADEN KLLKAVNPRS TGSDLDRAKL AEKVGGALRR LARIGIITRV GEQNSKKFII
     SEAVFRFGAD VRAGDDPREV QLRLIRDGEA TTPTLLTTEA IEFAEDGARD ELEESEAE