ID   MUKE_HAES1              Reviewed;         247 AA.
AC   Q0I3K1;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   03-OCT-2006, sequence version 1.
DT   25-MAY-2022, entry version 71.
DE   RecName: Full=Chromosome partition protein MukE {ECO:0000255|HAMAP-Rule:MF_01802};
GN   Name=mukE {ECO:0000255|HAMAP-Rule:MF_01802}; OrderedLocusNames=HS_0865;
OS   Haemophilus somnus (strain 129Pt) (Histophilus somni).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Histophilus.
OX   NCBI_TaxID=205914;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=129Pt;
RX   PubMed=17172329; DOI=10.1128/jb.01422-06;
RA   Challacombe J.F., Duncan A.J., Brettin T.S., Bruce D., Chertkov O.,
RA   Detter J.C., Han C.S., Misra M., Richardson P., Tapia R., Thayer N.,
RA   Xie G., Inzana T.J.;
RT   "Complete genome sequence of Haemophilus somnus (Histophilus somni) strain
RT   129Pt and comparison to Haemophilus ducreyi 35000HP and Haemophilus
RT   influenzae Rd.";
RL   J. Bacteriol. 189:1890-1898(2007).
CC   -!- FUNCTION: Involved in chromosome condensation, segregation and cell
CC       cycle progression. May participate in facilitating chromosome
CC       segregation by condensation DNA from both sides of a centrally located
CC       replisome during cell division. Probably acts via its interaction with
CC       MukB and MukF. {ECO:0000255|HAMAP-Rule:MF_01802}.
CC   -!- SUBUNIT: Interacts, and probably forms a ternary complex, with MukF and
CC       MukB. The complex formation is stimulated by calcium or magnesium.
CC       {ECO:0000255|HAMAP-Rule:MF_01802}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, nucleoid {ECO:0000255|HAMAP-
CC       Rule:MF_01802}. Note=Restricted to the nucleoid region.
CC       {ECO:0000255|HAMAP-Rule:MF_01802}.
CC   -!- SIMILARITY: Belongs to the MukE family. {ECO:0000255|HAMAP-
CC       Rule:MF_01802}.
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DR   EMBL; CP000436; ABI25140.1; -; Genomic_DNA.
DR   RefSeq; WP_011609018.1; NC_008309.1.
DR   AlphaFoldDB; Q0I3K1; -.
DR   SMR; Q0I3K1; -.
DR   STRING; 205914.HS_0865; -.
DR   EnsemblBacteria; ABI25140; ABI25140; HS_0865.
DR   GeneID; 56964895; -.
DR   KEGG; hso:HS_0865; -.
DR   eggNOG; COG3095; Bacteria.
DR   HOGENOM; CLU_1146408_0_0_6; -.
DR   OMA; FLMDYQE; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-UniRule.
DR   GO; GO:0009295; C:nucleoid; IEA:UniProtKB-SubCell.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0030261; P:chromosome condensation; IEA:UniProtKB-KW.
DR   GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.10.2250; -; 1.
DR   Gene3D; 1.10.10.2260; -; 1.
DR   HAMAP; MF_01802; MukE; 1.
DR   InterPro; IPR042037; MukE_C.
DR   InterPro; IPR042038; MukE_N.
DR   InterPro; IPR007385; Scp_MukE.
DR   Pfam; PF04288; MukE; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Chromosome partition; Cytoplasm;
KW   DNA condensation.
FT   CHAIN           1..247
FT                   /note="Chromosome partition protein MukE"
FT                   /id="PRO_1000069922"
FT   REGION          213..247
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   247 AA;  27967 MW;  66803155A1424E80 CRC64;
     MTDNIQDLLS IKLARAIANP LFPEVDSQLR SGKHIGQEYL DNYSFLADFQ HELDSFYRRY
     NVELIRAPEG FFYLRPKATT LIARSVLSEL EMLVGKVLCY LYLSPERLAQ QGIFTVQEVH
     DELINLADET KLLKAINLRA GGSDLDKQKL AEKVRSAISR LRRLGMIHAV GDQHSGKFTI
     SESVFRFGAE VRSGDDPLEA QLRLIREGEA ATAQSLQEEK NGLKDNMDQS AVENEQYFEN
     EENEGIA