ID   MUKE_HISS2              Reviewed;         247 AA.
AC   B0UU63;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   08-APR-2008, sequence version 1.
DT   25-MAY-2022, entry version 58.
DE   RecName: Full=Chromosome partition protein MukE {ECO:0000255|HAMAP-Rule:MF_01802};
GN   Name=mukE {ECO:0000255|HAMAP-Rule:MF_01802}; OrderedLocusNames=HSM_1340;
OS   Histophilus somni (strain 2336) (Haemophilus somnus).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Histophilus.
OX   NCBI_TaxID=228400;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=2336;
RG   US DOE Joint Genome Institute;
RA   Siddaramappa S., Duncan A.J., Challacombe J.F., Rainey D., Gillaspy A.F.,
RA   Carson M., Gipson J., Gipson M., Bruce D., Detter J.C., Han C.S., Land M.,
RA   Tapia R., Thompson L.S., Orvis J., Zaitshik J., Barnes G., Brettin T.S.,
RA   Dyer D.W., Inzana T.J.;
RT   "Complete sequence of Haemophilus somnus 2336.";
RL   Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Involved in chromosome condensation, segregation and cell
CC       cycle progression. May participate in facilitating chromosome
CC       segregation by condensation DNA from both sides of a centrally located
CC       replisome during cell division. Probably acts via its interaction with
CC       MukB and MukF. {ECO:0000255|HAMAP-Rule:MF_01802}.
CC   -!- SUBUNIT: Interacts, and probably forms a ternary complex, with MukF and
CC       MukB. The complex formation is stimulated by calcium or magnesium.
CC       {ECO:0000255|HAMAP-Rule:MF_01802}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, nucleoid {ECO:0000255|HAMAP-
CC       Rule:MF_01802}. Note=Restricted to the nucleoid region.
CC       {ECO:0000255|HAMAP-Rule:MF_01802}.
CC   -!- SIMILARITY: Belongs to the MukE family. {ECO:0000255|HAMAP-
CC       Rule:MF_01802}.
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DR   EMBL; CP000947; ACA31077.1; -; Genomic_DNA.
DR   RefSeq; WP_012340496.1; NC_010519.1.
DR   AlphaFoldDB; B0UU63; -.
DR   SMR; B0UU63; -.
DR   STRING; 228400.HSM_1340; -.
DR   EnsemblBacteria; ACA31077; ACA31077; HSM_1340.
DR   KEGG; hsm:HSM_1340; -.
DR   HOGENOM; CLU_1146408_0_0_6; -.
DR   OMA; FLMDYQE; -.
DR   OrthoDB; 1412262at2; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-UniRule.
DR   GO; GO:0009295; C:nucleoid; IEA:UniProtKB-SubCell.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0030261; P:chromosome condensation; IEA:UniProtKB-KW.
DR   GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.10.2250; -; 1.
DR   Gene3D; 1.10.10.2260; -; 1.
DR   HAMAP; MF_01802; MukE; 1.
DR   InterPro; IPR042037; MukE_C.
DR   InterPro; IPR042038; MukE_N.
DR   InterPro; IPR007385; Scp_MukE.
DR   Pfam; PF04288; MukE; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Chromosome partition; Cytoplasm;
KW   DNA condensation.
FT   CHAIN           1..247
FT                   /note="Chromosome partition protein MukE"
FT                   /id="PRO_1000088222"
FT   REGION          213..247
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   247 AA;  27940 MW;  C6803150C30B6A1B CRC64;
     MTDSIQDLLS IKLARAIANP LFPEVDSQLR SGKHIGQEYL DNYSFLADFQ HELDSFYRRY
     NVELIRAPEG FFYLRPKATT LIARSVLSEL EMLVGKVLCY LYLSPERLAQ QGIFTVQEVH
     DELINLADET KLLKAINLRA GGSDLDKQKL AEKVRSAISR LRRLGMIHAV GDQHSGKFTI
     SESVFRFGAE VRSGDDPLEA QLRLIREGEA ATAQSLQEEK NGLKDNMDQS AVENEQYFEN
     EENEGIA