MUKE_PHOPR
ID MUKE_PHOPR Reviewed; 235 AA.
AC Q6LPL4;
DT 21-DEC-2004, integrated into UniProtKB/Swiss-Prot.
DT 15-JAN-2008, sequence version 3.
DT 25-MAY-2022, entry version 79.
DE RecName: Full=Chromosome partition protein MukE {ECO:0000255|HAMAP-Rule:MF_01802};
GN Name=mukE {ECO:0000255|HAMAP-Rule:MF_01802}; OrderedLocusNames=PBPRA2377;
OS Photobacterium profundum (strain SS9).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Photobacterium.
OX NCBI_TaxID=298386;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-1253 / SS9;
RX PubMed=15746425; DOI=10.1126/science.1103341;
RA Vezzi A., Campanaro S., D'Angelo M., Simonato F., Vitulo N., Lauro F.M.,
RA Cestaro A., Malacrida G., Simionati B., Cannata N., Romualdi C.,
RA Bartlett D.H., Valle G.;
RT "Life at depth: Photobacterium profundum genome sequence and expression
RT analysis.";
RL Science 307:1459-1461(2005).
CC -!- FUNCTION: Involved in chromosome condensation, segregation and cell
CC cycle progression. May participate in facilitating chromosome
CC segregation by condensation DNA from both sides of a centrally located
CC replisome during cell division. Probably acts via its interaction with
CC MukB and MukF. {ECO:0000255|HAMAP-Rule:MF_01802}.
CC -!- SUBUNIT: Interacts, and probably forms a ternary complex, with MukF and
CC MukB. The complex formation is stimulated by calcium or magnesium.
CC {ECO:0000255|HAMAP-Rule:MF_01802}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, nucleoid {ECO:0000255|HAMAP-
CC Rule:MF_01802}. Note=Restricted to the nucleoid region.
CC {ECO:0000255|HAMAP-Rule:MF_01802}.
CC -!- SIMILARITY: Belongs to the MukE family. {ECO:0000255|HAMAP-
CC Rule:MF_01802}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAG20762.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; CR378670; CAG20762.1; ALT_INIT; Genomic_DNA.
DR AlphaFoldDB; Q6LPL4; -.
DR SMR; Q6LPL4; -.
DR STRING; 298386.PBPRA2377; -.
DR PRIDE; Q6LPL4; -.
DR EnsemblBacteria; CAG20762; CAG20762; PBPRA2377.
DR KEGG; ppr:PBPRA2377; -.
DR eggNOG; COG3095; Bacteria.
DR HOGENOM; CLU_1146408_0_0_6; -.
DR Proteomes; UP000000593; Chromosome 1.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-UniRule.
DR GO; GO:0009295; C:nucleoid; IEA:UniProtKB-SubCell.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0030261; P:chromosome condensation; IEA:UniProtKB-KW.
DR GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-UniRule.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.10.2250; -; 1.
DR Gene3D; 1.10.10.2260; -; 1.
DR HAMAP; MF_01802; MukE; 1.
DR InterPro; IPR042037; MukE_C.
DR InterPro; IPR042038; MukE_N.
DR InterPro; IPR007385; Scp_MukE.
DR Pfam; PF04288; MukE; 1.
PE 3: Inferred from homology;
KW Cell cycle; Cell division; Chromosome partition; Cytoplasm;
KW DNA condensation; Reference proteome.
FT CHAIN 1..235
FT /note="Chromosome partition protein MukE"
FT /id="PRO_0000206800"
FT REGION 204..235
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 217..235
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 235 AA; 26809 MW; C02C8F8CD506CED4 CRC64;
MPEKLAKAIA NPLFPALDNA LRSGRHVSSE DLDNHALLIE FERELGMFYR RYNTELIRAP
EGFFYLRPRS TSLIGRSVLS EIDMLVGKVL CFLYLSPERL AHEGIFTNQE LFDELLVLAD
EKKLMKFVTH RASGSDLDRE KLYDKVKTSL RRLRRIGMLI PIGENGKFRI SESVFRFGAD
VRTGDDVREA QLRLIRDGEA VVHQQEPSQS SLLDGFDADD TGHHDSELTM QEGEV
