ID   MUKE_VIBCH              Reviewed;         231 AA.
AC   Q9KRC7;
DT   16-JAN-2004, integrated into UniProtKB/Swiss-Prot.
DT   15-JAN-2008, sequence version 3.
DT   25-MAY-2022, entry version 86.
DE   RecName: Full=Chromosome partition protein MukE {ECO:0000255|HAMAP-Rule:MF_01802};
GN   Name=mukE {ECO:0000255|HAMAP-Rule:MF_01802}; OrderedLocusNames=VC_1715;
OS   Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=243277;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 39315 / El Tor Inaba N16961;
RX   PubMed=10952301; DOI=10.1038/35020000;
RA   Heidelberg J.F., Eisen J.A., Nelson W.C., Clayton R.A., Gwinn M.L.,
RA   Dodson R.J., Haft D.H., Hickey E.K., Peterson J.D., Umayam L.A., Gill S.R.,
RA   Nelson K.E., Read T.D., Tettelin H., Richardson D.L., Ermolaeva M.D.,
RA   Vamathevan J.J., Bass S., Qin H., Dragoi I., Sellers P., McDonald L.A.,
RA   Utterback T.R., Fleischmann R.D., Nierman W.C., White O., Salzberg S.L.,
RA   Smith H.O., Colwell R.R., Mekalanos J.J., Venter J.C., Fraser C.M.;
RT   "DNA sequence of both chromosomes of the cholera pathogen Vibrio
RT   cholerae.";
RL   Nature 406:477-483(2000).
CC   -!- FUNCTION: Involved in chromosome condensation, segregation and cell
CC       cycle progression. May participate in facilitating chromosome
CC       segregation by condensation DNA from both sides of a centrally located
CC       replisome during cell division. Probably acts via its interaction with
CC       MukB and MukF. {ECO:0000255|HAMAP-Rule:MF_01802}.
CC   -!- SUBUNIT: Interacts, and probably forms a ternary complex, with MukF and
CC       MukB. The complex formation is stimulated by calcium or magnesium.
CC       {ECO:0000255|HAMAP-Rule:MF_01802}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, nucleoid {ECO:0000255|HAMAP-
CC       Rule:MF_01802}. Note=Restricted to the nucleoid region.
CC       {ECO:0000255|HAMAP-Rule:MF_01802}.
CC   -!- SIMILARITY: Belongs to the MukE family. {ECO:0000255|HAMAP-
CC       Rule:MF_01802}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAF94865.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AE003852; AAF94865.1; ALT_INIT; Genomic_DNA.
DR   PIR; E82166; E82166.
DR   RefSeq; NP_231351.1; NC_002505.1.
DR   AlphaFoldDB; Q9KRC7; -.
DR   SMR; Q9KRC7; -.
DR   STRING; 243277.VC_1715; -.
DR   DNASU; 2613720; -.
DR   EnsemblBacteria; AAF94865; AAF94865; VC_1715.
DR   KEGG; vch:VC_1715; -.
DR   PATRIC; fig|243277.26.peg.1641; -.
DR   eggNOG; COG3095; Bacteria.
DR   HOGENOM; CLU_1146408_0_0_6; -.
DR   OMA; FLMDYQE; -.
DR   Proteomes; UP000000584; Chromosome 1.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-UniRule.
DR   GO; GO:0009295; C:nucleoid; IEA:UniProtKB-SubCell.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0030261; P:chromosome condensation; IEA:UniProtKB-KW.
DR   GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.10.2250; -; 1.
DR   Gene3D; 1.10.10.2260; -; 1.
DR   HAMAP; MF_01802; MukE; 1.
DR   InterPro; IPR042037; MukE_C.
DR   InterPro; IPR042038; MukE_N.
DR   InterPro; IPR007385; Scp_MukE.
DR   Pfam; PF04288; MukE; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Chromosome partition; Cytoplasm;
KW   DNA condensation; Reference proteome.
FT   CHAIN           1..231
FT                   /note="Chromosome partition protein MukE"
FT                   /id="PRO_0000206804"
FT   REGION          204..231
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        204..218
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   231 AA;  26442 MW;  BFA43B9A1796E0D9 CRC64;
     MPENLAKAIA NPLFPALDSL LRAGRHVSSD DLDNHAFLSD FEPDLALFYQ RYHTELVRAP
     EGFFYLRPRS TSLINRSVLS ELDMLVGKVL CFLYLSPERL AHEGIFTNQE LYDELLTLVE
     EKKLMKLVTN RASGSDLDRE KLFEKVRTSL RRLRRLGMVI TIGDTGKFRI TEAVFRFGAD
     VRLGGDVREA QLRLIRDGEA VVHTPEPSQQ SLLENPTAEY DEEQTEWEDE A