MUKE_VIBPA
ID MUKE_VIBPA Reviewed; 232 AA.
AC Q87QW3;
DT 16-JAN-2004, integrated into UniProtKB/Swiss-Prot.
DT 15-JAN-2008, sequence version 3.
DT 25-MAY-2022, entry version 88.
DE RecName: Full=Chromosome partition protein MukE {ECO:0000255|HAMAP-Rule:MF_01802};
GN Name=mukE {ECO:0000255|HAMAP-Rule:MF_01802}; OrderedLocusNames=VP1036;
OS Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Vibrio.
OX NCBI_TaxID=223926;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RIMD 2210633;
RX PubMed=12620739; DOI=10.1016/s0140-6736(03)12659-1;
RA Makino K., Oshima K., Kurokawa K., Yokoyama K., Uda T., Tagomori K.,
RA Iijima Y., Najima M., Nakano M., Yamashita A., Kubota Y., Kimura S.,
RA Yasunaga T., Honda T., Shinagawa H., Hattori M., Iida T.;
RT "Genome sequence of Vibrio parahaemolyticus: a pathogenic mechanism
RT distinct from that of V. cholerae.";
RL Lancet 361:743-749(2003).
CC -!- FUNCTION: Involved in chromosome condensation, segregation and cell
CC cycle progression. May participate in facilitating chromosome
CC segregation by condensation DNA from both sides of a centrally located
CC replisome during cell division. Probably acts via its interaction with
CC MukB and MukF. {ECO:0000255|HAMAP-Rule:MF_01802}.
CC -!- SUBUNIT: Interacts, and probably forms a ternary complex, with MukF and
CC MukB. The complex formation is stimulated by calcium or magnesium.
CC {ECO:0000255|HAMAP-Rule:MF_01802}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, nucleoid {ECO:0000255|HAMAP-
CC Rule:MF_01802}. Note=Restricted to the nucleoid region.
CC {ECO:0000255|HAMAP-Rule:MF_01802}.
CC -!- SIMILARITY: Belongs to the MukE family. {ECO:0000255|HAMAP-
CC Rule:MF_01802}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAC59299.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; BA000031; BAC59299.1; ALT_INIT; Genomic_DNA.
DR RefSeq; NP_797415.1; NC_004603.1.
DR AlphaFoldDB; Q87QW3; -.
DR SMR; Q87QW3; -.
DR STRING; 223926.28806023; -.
DR EnsemblBacteria; BAC59299; BAC59299; BAC59299.
DR KEGG; vpa:VP1036; -.
DR PATRIC; fig|223926.6.peg.982; -.
DR eggNOG; COG3095; Bacteria.
DR HOGENOM; CLU_1146408_0_0_6; -.
DR OMA; FLMDYQE; -.
DR Proteomes; UP000002493; Chromosome 1.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-UniRule.
DR GO; GO:0009295; C:nucleoid; IEA:UniProtKB-SubCell.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0030261; P:chromosome condensation; IEA:UniProtKB-KW.
DR GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-UniRule.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.10.2250; -; 1.
DR Gene3D; 1.10.10.2260; -; 1.
DR HAMAP; MF_01802; MukE; 1.
DR InterPro; IPR042037; MukE_C.
DR InterPro; IPR042038; MukE_N.
DR InterPro; IPR007385; Scp_MukE.
DR Pfam; PF04288; MukE; 1.
PE 3: Inferred from homology;
KW Cell cycle; Cell division; Chromosome partition; Cytoplasm;
KW DNA condensation; Reference proteome.
FT CHAIN 1..232
FT /note="Chromosome partition protein MukE"
FT /id="PRO_0000206805"
FT REGION 203..232
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 217..232
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 232 AA; 26275 MW; CA883EA993618A92 CRC64;
MSDNLAKAIS NPLFPALDSM LRAGRHISTE DLDNHALLSD FELELSSFYQ RYNTELVKAP
EGFFYLRPRS TSLIGRSVLS ELDMLVGKVL CFLYLSPERL AHEGIFTNQE LYDELLALAD
EKKLMKLVTN RATGSDLDKE KLFEKVRTSL RRLRRLGMII NIGETGKFSI SEAVFRFGAD
VRVGDDIREA QLRLIRDGEA VVHTKEPSQG SLLSEEDQEE QAQEEMTEEG EA
