ID   MUKF_PHOLL              Reviewed;         440 AA.
AC   Q7N6B9;
DT   16-JAN-2004, integrated into UniProtKB/Swiss-Prot.
DT   15-DEC-2003, sequence version 1.
DT   03-AUG-2022, entry version 111.
DE   RecName: Full=Chromosome partition protein MukF {ECO:0000255|HAMAP-Rule:MF_01803};
GN   Name=mukF {ECO:0000255|HAMAP-Rule:MF_01803}; OrderedLocusNames=plu1637;
OS   Photorhabdus laumondii subsp. laumondii (strain DSM 15139 / CIP 105565 /
OS   TT01).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Morganellaceae; Photorhabdus.
OX   NCBI_TaxID=243265;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 15139 / CIP 105565 / TT01;
RX   PubMed=14528314; DOI=10.1038/nbt886;
RA   Duchaud E., Rusniok C., Frangeul L., Buchrieser C., Givaudan A.,
RA   Taourit S., Bocs S., Boursaux-Eude C., Chandler M., Charles J.-F.,
RA   Dassa E., Derose R., Derzelle S., Freyssinet G., Gaudriault S., Medigue C.,
RA   Lanois A., Powell K., Siguier P., Vincent R., Wingate V., Zouine M.,
RA   Glaser P., Boemare N., Danchin A., Kunst F.;
RT   "The genome sequence of the entomopathogenic bacterium Photorhabdus
RT   luminescens.";
RL   Nat. Biotechnol. 21:1307-1313(2003).
CC   -!- FUNCTION: Involved in chromosome condensation, segregation and cell
CC       cycle progression. May participate in facilitating chromosome
CC       segregation by condensation DNA from both sides of a centrally located
CC       replisome during cell division. Not required for mini-F plasmid
CC       partitioning. Probably acts via its interaction with MukB and MukE.
CC       Overexpression results in anucleate cells. It has a calcium binding
CC       activity. {ECO:0000255|HAMAP-Rule:MF_01803}.
CC   -!- SUBUNIT: Interacts, and probably forms a ternary complex, with MukE and
CC       MukB via its C-terminal region. The complex formation is stimulated by
CC       calcium or magnesium. It is required for an interaction between MukE
CC       and MukB. {ECO:0000255|HAMAP-Rule:MF_01803}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, nucleoid {ECO:0000255|HAMAP-
CC       Rule:MF_01803}. Note=Restricted to the nucleoid region.
CC       {ECO:0000255|HAMAP-Rule:MF_01803}.
CC   -!- SIMILARITY: Belongs to the MukF family. {ECO:0000255|HAMAP-
CC       Rule:MF_01803}.
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DR   EMBL; BX571864; CAE13930.1; -; Genomic_DNA.
DR   RefSeq; WP_011145928.1; NC_005126.1.
DR   AlphaFoldDB; Q7N6B9; -.
DR   SMR; Q7N6B9; -.
DR   STRING; 243265.plu1637; -.
DR   EnsemblBacteria; CAE13930; CAE13930; plu1637.
DR   GeneID; 24166989; -.
DR   KEGG; plu:plu1637; -.
DR   eggNOG; COG3006; Bacteria.
DR   HOGENOM; CLU_049853_0_0_6; -.
DR   OMA; AIYNNER; -.
DR   OrthoDB; 231724at2; -.
DR   BioCyc; PLUM243265:PLU_RS08240-MON; -.
DR   Proteomes; UP000002514; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-UniRule.
DR   GO; GO:0009295; C:nucleoid; IEA:UniProtKB-SubCell.
DR   GO; GO:0005509; F:calcium ion binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0030261; P:chromosome condensation; IEA:UniProtKB-KW.
DR   GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd16337; MukF_C; 1.
DR   Gene3D; 1.10.10.10; -; 1.
DR   Gene3D; 1.10.225.40; -; 1.
DR   Gene3D; 1.20.58.590; -; 1.
DR   HAMAP; MF_01803; MukF; 1.
DR   InterPro; IPR005582; Chromosome_partition_MukF.
DR   InterPro; IPR033441; MukF_C.
DR   InterPro; IPR038198; MukF_C_sf.
DR   InterPro; IPR033440; MukF_M.
DR   InterPro; IPR036141; MukF_M_sp.
DR   InterPro; IPR033439; MukF_WHTH.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF03882; KicB; 1.
DR   Pfam; PF17193; MukF_C; 1.
DR   Pfam; PF17192; MukF_M; 1.
DR   PIRSF; PIRSF018282; MukF; 1.
DR   SUPFAM; SSF140570; SSF140570; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
PE   3: Inferred from homology;
KW   Calcium; Cell cycle; Cell division; Chromosome partition; Cytoplasm;
KW   DNA condensation; Reference proteome.
FT   CHAIN           1..440
FT                   /note="Chromosome partition protein MukF"
FT                   /id="PRO_0000211608"
FT   REGION          208..236
FT                   /note="Leucine-zipper"
SQ   SEQUENCE   440 AA;  50254 MW;  4056A090FA6CC659 CRC64;
     MSEYSQTVPE LVSWARKNDF SISLPVERLA FLMAIAVLNS ERLDGEMSES ELVDAFREVC
     KGFEQTTESV AVRANNAIND MVRQKLLNRF TSELADNNAI YRLTPLGMGI SDYYIRQREF
     STLRLSMQLS VVASELHRAA EAAEEGGDEF HWHRNVFAPL KYSVAEIFDS IDMSQRVMDE
     QQSSVKEDIA ALLNQDWQAA IANCEQLLSE TSGTLRELQD TLEAAGDKLQ ANLLRIQEAN
     MDSGGSELVD KLVFDLQSKL DRIISWGQQA IDLWIGYDRH VHKFIRTAID MDKNRIFSQR
     LRQSVQHYFD NPWTLTIANA ERLLDMRDEE LTLRNEEVTG ELPLALEYEE FSEINEQLAE
     MIEKALLIYR QEQRPLDLGA VLRDYLAQHP LSRHFDVARI LVDQAVRLGV AEADFSGLPA
     EWLAINDYGA KVQAHVIDTY