ID   MUKF_VIBC1              Reviewed;         445 AA.
AC   A7N1J9;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   02-OCT-2007, sequence version 1.
DT   03-AUG-2022, entry version 81.
DE   RecName: Full=Chromosome partition protein MukF {ECO:0000255|HAMAP-Rule:MF_01803};
GN   Name=mukF {ECO:0000255|HAMAP-Rule:MF_01803};
GN   OrderedLocusNames=VIBHAR_01587;
OS   Vibrio campbellii (strain ATCC BAA-1116).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=2902295;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-1116 / BB120;
RG   The Vibrio harveyi Genome Sequencing Project;
RA   Bassler B., Clifton S.W., Fulton L., Delehaunty K., Fronick C.,
RA   Harrison M., Markivic C., Fulton R., Tin-Wollam A.-M., Shah N., Pepin K.,
RA   Nash W., Thiruvilangam P., Bhonagiri V., Waters C., Tu K.C., Irgon J.,
RA   Wilson R.K.;
RL   Submitted (AUG-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Involved in chromosome condensation, segregation and cell
CC       cycle progression. May participate in facilitating chromosome
CC       segregation by condensation DNA from both sides of a centrally located
CC       replisome during cell division. Not required for mini-F plasmid
CC       partitioning. Probably acts via its interaction with MukB and MukE.
CC       Overexpression results in anucleate cells. It has a calcium binding
CC       activity. {ECO:0000255|HAMAP-Rule:MF_01803}.
CC   -!- SUBUNIT: Interacts, and probably forms a ternary complex, with MukE and
CC       MukB via its C-terminal region. The complex formation is stimulated by
CC       calcium or magnesium. It is required for an interaction between MukE
CC       and MukB. {ECO:0000255|HAMAP-Rule:MF_01803}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, nucleoid {ECO:0000255|HAMAP-
CC       Rule:MF_01803}. Note=Restricted to the nucleoid region.
CC       {ECO:0000255|HAMAP-Rule:MF_01803}.
CC   -!- SIMILARITY: Belongs to the MukF family. {ECO:0000255|HAMAP-
CC       Rule:MF_01803}.
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DR   EMBL; CP000789; ABU70557.1; -; Genomic_DNA.
DR   RefSeq; WP_005426221.1; NC_022269.1.
DR   AlphaFoldDB; A7N1J9; -.
DR   SMR; A7N1J9; -.
DR   EnsemblBacteria; ABU70557; ABU70557; VIBHAR_01587.
DR   KEGG; vha:VIBHAR_01587; -.
DR   PATRIC; fig|338187.25.peg.1075; -.
DR   OMA; AIYNNER; -.
DR   OrthoDB; 231724at2; -.
DR   Proteomes; UP000008152; Chromosome I.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-UniRule.
DR   GO; GO:0009295; C:nucleoid; IEA:UniProtKB-SubCell.
DR   GO; GO:0005509; F:calcium ion binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0030261; P:chromosome condensation; IEA:UniProtKB-KW.
DR   GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd16337; MukF_C; 1.
DR   Gene3D; 1.10.10.10; -; 1.
DR   Gene3D; 1.10.225.40; -; 1.
DR   Gene3D; 1.20.58.590; -; 1.
DR   HAMAP; MF_01803; MukF; 1.
DR   InterPro; IPR005582; Chromosome_partition_MukF.
DR   InterPro; IPR033441; MukF_C.
DR   InterPro; IPR038198; MukF_C_sf.
DR   InterPro; IPR033440; MukF_M.
DR   InterPro; IPR036141; MukF_M_sp.
DR   InterPro; IPR033439; MukF_WHTH.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF03882; KicB; 1.
DR   Pfam; PF17193; MukF_C; 1.
DR   Pfam; PF17192; MukF_M; 1.
DR   PIRSF; PIRSF018282; MukF; 1.
DR   SUPFAM; SSF140570; SSF140570; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
PE   3: Inferred from homology;
KW   Calcium; Cell cycle; Cell division; Chromosome partition; Cytoplasm;
KW   DNA condensation.
FT   CHAIN           1..445
FT                   /note="Chromosome partition protein MukF"
FT                   /id="PRO_1000069944"
FT   REGION          213..241
FT                   /note="Leucine-zipper"
SQ   SEQUENCE   445 AA;  51015 MW;  487A6F0A7DABE63E CRC64;
     MSEMTLNAAE QPIDELVGWV KQHDFSLNLT TERLAFLIAI AVLSNERFDE ELGEGELHDA
     FAIVTRLFDE TGEASAFRAN NAINEMVKQR LISRFVSEIT DGASIYRLSP LAIGITDYYV
     RHREFSKLRL SIQLSMVADE MAKAIEAAQK GGTPGHWKKN VYGILKYSVG EIFDQIDLNQ
     RVMDEQQQSV KQQIADLLNK DWREAINNCE ALLSETSSTL RELQDTLQAA SDELQTQILD
     IQEIVYGDPE LEFIEEALFG LQMKLDRITS WGQQAIDLWI GYDRHVHKFI RTAIDMDKNR
     AFSSRLRQSV KDYFDSPWYL TYADAERLSD LRDEALVLRD DEVTGQVPME VEYEEFQQVN
     DELAERIGDM LKAHKDQGAP IDLSVVLRDY LAQHPHTHHF DLARIVVDQA VRLGYSESDY
     QAVQPDWKAI NEFGAKVQAN VIDRY