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MUP_CAVPO
ID   MUP_CAVPO               Reviewed;          15 AA.
AC   P83507;
DT   03-JUL-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2003, sequence version 1.
DT   11-DEC-2019, entry version 43.
DE   RecName: Full=Major urinary protein;
DE            Short=MUP;
DE   AltName: Allergen=Cav p 1;
DE   Flags: Fragment;
OS   Cavia porcellus (Guinea pig).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Caviidae;
OC   Cavia.
OX   NCBI_TaxID=10141 {ECO:0000305};
RN   [1] {ECO:0000305}
RP   PROTEIN SEQUENCE, AND ALLERGEN.
RC   STRAIN=Dunkin-Hartley; TISSUE=Hair;
RX   PubMed=11972481; DOI=10.1034/j.1398-9995.2002.13540.x;
RA   Fahlbusch B., Rudeschko O., Szilagyi U., Schlott B., Henzgen M.,
RA   Schlenvoigt G., Schubert H.;
RT   "Purification and partial characterization of the major allergen, Cav p 1,
RT   from guinea pig Cavia porcellus.";
RL   Allergy 57:417-422(2002).
CC   -!- FUNCTION: Binds pheromones that are released from drying urine of
CC       males. These pheromones affect the sexual behavior of females (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC   -!- ALLERGEN: Causes an allergic reaction in human. Binds to IgE. Is a
CC       cause of guinea pig hair allergy. {ECO:0000269|PubMed:11972481}.
CC   -!- SIMILARITY: Belongs to the calycin superfamily. Lipocalin family.
CC       {ECO:0000305}.
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DR   Allergome; 195; Cav p 1.
DR   Allergome; 3184; Cav p 1.0101.
DR   Proteomes; UP000005447; Unassembled WGS sequence.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0019863; F:IgE binding; IDA:UniProtKB.
DR   GO; GO:0005550; F:pheromone binding; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Allergen; Direct protein sequencing; Pheromone-binding; Reference proteome;
KW   Secreted; Transport.
FT   CHAIN           1..>15
FT                   /note="Major urinary protein"
FT                   /id="PRO_0000201022"
FT   NON_TER         15
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   15 AA;  1606 MW;  1F32C67081A8167B CRC64;
     SEINGDWNTI ALSAD
 
 
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