MUP_CAVPO
ID MUP_CAVPO Reviewed; 15 AA.
AC P83507;
DT 03-JUL-2003, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 11-DEC-2019, entry version 43.
DE RecName: Full=Major urinary protein;
DE Short=MUP;
DE AltName: Allergen=Cav p 1;
DE Flags: Fragment;
OS Cavia porcellus (Guinea pig).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Caviidae;
OC Cavia.
OX NCBI_TaxID=10141 {ECO:0000305};
RN [1] {ECO:0000305}
RP PROTEIN SEQUENCE, AND ALLERGEN.
RC STRAIN=Dunkin-Hartley; TISSUE=Hair;
RX PubMed=11972481; DOI=10.1034/j.1398-9995.2002.13540.x;
RA Fahlbusch B., Rudeschko O., Szilagyi U., Schlott B., Henzgen M.,
RA Schlenvoigt G., Schubert H.;
RT "Purification and partial characterization of the major allergen, Cav p 1,
RT from guinea pig Cavia porcellus.";
RL Allergy 57:417-422(2002).
CC -!- FUNCTION: Binds pheromones that are released from drying urine of
CC males. These pheromones affect the sexual behavior of females (By
CC similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC -!- ALLERGEN: Causes an allergic reaction in human. Binds to IgE. Is a
CC cause of guinea pig hair allergy. {ECO:0000269|PubMed:11972481}.
CC -!- SIMILARITY: Belongs to the calycin superfamily. Lipocalin family.
CC {ECO:0000305}.
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DR Allergome; 195; Cav p 1.
DR Allergome; 3184; Cav p 1.0101.
DR Proteomes; UP000005447; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0019863; F:IgE binding; IDA:UniProtKB.
DR GO; GO:0005550; F:pheromone binding; IEA:UniProtKB-KW.
PE 1: Evidence at protein level;
KW Allergen; Direct protein sequencing; Pheromone-binding; Reference proteome;
KW Secreted; Transport.
FT CHAIN 1..>15
FT /note="Major urinary protein"
FT /id="PRO_0000201022"
FT NON_TER 15
FT /evidence="ECO:0000305"
SQ SEQUENCE 15 AA; 1606 MW; 1F32C67081A8167B CRC64;
SEINGDWNTI ALSAD