9DC1_SOLPI
ID 9DC1_SOLPI Reviewed; 863 AA.
AC P0DO05; Q946D6;
DT 31-JAN-2018, integrated into UniProtKB/Swiss-Prot.
DT 31-JAN-2018, sequence version 1.
DT 25-MAY-2022, entry version 9.
DE RecName: Full=Receptor-like protein 9DC1 {ECO:0000312|EMBL:AAT77548.1};
DE Flags: Precursor;
GN Name=9DC1 {ECO:0000312|EMBL:AAT77548.1};
GN Synonyms=9DC {ECO:0000312|EMBL:AAK97628.1};
OS Solanum pimpinellifolium (Currant tomato) (Lycopersicon pimpinellifolium).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum;
OC Solanum subgen. Lycopersicon.
OX NCBI_TaxID=4084;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND FUNCTION.
RC STRAIN=cv. LA1301;
RX PubMed=11517316; DOI=10.1073/pnas.181241798;
RA Van Der Hoorn R.A.L., Kruijt M., Roth R., Brandwagt B.F., Joosten M.H.A.J.,
RA De Wit P.J.G.M.;
RT "Intragenic recombination generated two distinct Cf genes that mediate AVR9
RT recognition in the natural population of Lycopersicon pimpinellifolium.";
RL Proc. Natl. Acad. Sci. U.S.A. 98:10493-10498(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND FUNCTION.
RC STRAIN=cv. LA1301;
RX PubMed=15579714; DOI=10.1534/genetics.104.028985;
RA Kruijt M., Brandwagt B.F., de Wit P.J.;
RT "Rearrangements in the Cf-9 disease resistance gene cluster of wild tomato
RT have resulted in three genes that mediate Avr9 responsiveness.";
RL Genetics 168:1655-1663(2004).
CC -!- FUNCTION: Involved in plant defense. Confers resistance to the fungal
CC pathogen C.fulvum through recognition of the AVR9 elicitor protein.
CC {ECO:0000269|PubMed:11517316, ECO:0000269|PubMed:15579714}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Single-pass type I
CC membrane protein {ECO:0000305}.
CC -!- DOMAIN: The extracellular leucine-rich repeats are required for the
CC specificity of the elicitor protein recognition.
CC {ECO:0000250|UniProtKB:Q40235}.
CC -!- SIMILARITY: Belongs to the RLP family. {ECO:0000305}.
CC -!- CAUTION: In cv. LA101, 9DC1 results from the rearrangement in the Cf-9
CC disease resistance gene cluster between Cf-9 and Hcr9-9D, both
CC originating from the cv. Cf9. {ECO:0000305|PubMed:15579714}.
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DR EMBL; AF401036; AAK97628.1; -; Genomic_DNA.
DR EMBL; AY569331; AAT77548.1; -; Genomic_DNA.
DR AlphaFoldDB; P0DO05; -.
DR SMR; P0DO05; -.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0050832; P:defense response to fungus; IDA:UniProtKB.
DR Gene3D; 3.80.10.10; -; 4.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR013210; LRR_N_plant-typ.
DR Pfam; PF00560; LRR_1; 1.
DR Pfam; PF13855; LRR_8; 4.
DR Pfam; PF08263; LRRNT_2; 1.
DR SMART; SM00369; LRR_TYP; 7.
PE 3: Inferred from homology;
KW Cell membrane; Glycoprotein; Leucine-rich repeat; Membrane; Plant defense;
KW Receptor; Repeat; Signal; Transmembrane; Transmembrane helix.
FT SIGNAL 1..21
FT /evidence="ECO:0000255"
FT CHAIN 22..863
FT /note="Receptor-like protein 9DC1"
FT /id="PRO_5007715774"
FT TOPO_DOM 22..812
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 813..833
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 834..863
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT REPEAT 91..114
FT /note="LRR 1; degenerate"
FT /evidence="ECO:0000305"
FT REPEAT 115..138
FT /note="LRR 2"
FT /evidence="ECO:0000255"
FT REPEAT 140..163
FT /note="LRR 3"
FT /evidence="ECO:0000255"
FT REPEAT 164..190
FT /note="LRR 4; degenerate"
FT /evidence="ECO:0000305"
FT REPEAT 191..213
FT /note="LRR 5"
FT /evidence="ECO:0000255"
FT REPEAT 214..237
FT /note="LRR 6"
FT /evidence="ECO:0000255"
FT REPEAT 240..262
FT /note="LRR 7"
FT /evidence="ECO:0000255"
FT REPEAT 264..286
FT /note="LRR 8"
FT /evidence="ECO:0000255"
FT REPEAT 287..311
FT /note="LRR 9"
FT /evidence="ECO:0000255"
FT REPEAT 312..336
FT /note="LRR 10"
FT /evidence="ECO:0000255"
FT REPEAT 337..357
FT /note="LRR 11; degenerate"
FT /evidence="ECO:0000305"
FT REPEAT 358..382
FT /note="LRR 12"
FT /evidence="ECO:0000255"
FT REPEAT 383..406
FT /note="LRR 13"
FT /evidence="ECO:0000255"
FT REPEAT 408..428
FT /note="LRR 14"
FT /evidence="ECO:0000255"
FT REPEAT 429..452
FT /note="LRR 15"
FT /evidence="ECO:0000255"
FT REPEAT 454..476
FT /note="LRR 16"
FT /evidence="ECO:0000255"
FT REPEAT 477..500
FT /note="LRR 17"
FT /evidence="ECO:0000255"
FT REPEAT 502..524
FT /note="LRR 18"
FT /evidence="ECO:0000255"
FT REPEAT 525..549
FT /note="LRR 19"
FT /evidence="ECO:0000255"
FT REPEAT 551..572
FT /note="LRR 20"
FT /evidence="ECO:0000255"
FT REPEAT 573..597
FT /note="LRR 21"
FT /evidence="ECO:0000255"
FT REPEAT 599..623
FT /note="LRR 22"
FT /evidence="ECO:0000255"
FT REPEAT 667..690
FT /note="LRR 23"
FT /evidence="ECO:0000255"
FT REPEAT 691..714
FT /note="LRR 24"
FT /evidence="ECO:0000255"
FT REPEAT 715..739
FT /note="LRR 25"
FT /evidence="ECO:0000255"
FT REPEAT 741..759
FT /note="LRR 26"
FT /evidence="ECO:0000255"
FT REGION 24..90
FT /note="N-cap"
FT /evidence="ECO:0000305|PubMed:11517316"
FT REGION 760..812
FT /note="C-cap/acidic domain"
FT /evidence="ECO:0000305|PubMed:11517316"
FT CARBOHYD 71
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 108
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 190
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 203
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 211
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 261
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 299
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 310
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 378
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 396
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 416
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 464
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 519
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 563
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 674
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 698
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 714
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 746
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 767
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
SQ SEQUENCE 863 AA; 96522 MW; A6ACB7B3BC12AD40 CRC64;
MGCVKLVFFM LYVFLFQLVS SSSLPHLCPE DQALALLQFK NMFTVNPNAF HYCPDITGRE
IQSYPRTLSW NKSTSCCSWD GVHCDETTGQ VIALDLRCSQ LQGKFHSNSS LFQLSNLKRL
DLSNNNFIGS LISPKFGEFS DLTHLDLSDS SFTGVIPSEI SHLSKLHVLL IGDQYGLSIV
PHNFEPLLKN LTQLRELNLY EVNLSSTVPS NFSSHLTTLQ LSGTGLRGLL PERVFHLSDL
EFLDLSYNSQ LMVRFPTTKW NSSASLMKLY VHSVNIADRI PESFSHLTSL HELDMGYTNL
SGPIPKPLWN LTNIESLDLR YNHLEGPIPQ LPIFEKLKKL SLFRNDNLDG GLEFLSFNTQ
LERLDLSSNS LTGPIPSNIS GLQNLECLYL SSNHLNGSIP SWIFSLPSLV ELDLSNNTFS
GKIQEFKSKT LSAVTLKQNK LKGRIPNSLL NQKNLQLLLL SHNNISGHIS SAICNLKTLI
LLDLGSNNLE GTIPQCVVER NEYLSHLDLS KNRLSGTINT TFSVGNILRV ISLHGNKLTG
KVPRSMINCK YLTLLDLGNN MLNDTFPNWL GYLFQLKILS LRSNKLHGPI KSSGNTNLFM
GLQILDLSSN GFSGNLPERI LGNLQTMKEI DESTGFPEYI SDPYDIYYNY LTTISTKGQD
YDSVRILDSN MIINLSKNRF EGHIPSIIGD LVGLRTLNLS HNVLEGHIPA SFQNLSVLES
LDLSSNKISG EIPQQLASLT FLEVLNLSHN HLVGCIPKGK QFDSFGNTSY QGNDGLRGFP
LSKLCGGEDQ VTTPAELDQE EEEEDSPMIS WQGVLVGYGC GLVIGLSVIY IMWSTQYPAW
FSRMDLKLEH IITTKMKKHK KRY
