MURE_ORYSJ
ID MURE_ORYSJ Reviewed; 757 AA.
AC Q94LU9; Q7XCG3;
DT 25-OCT-2017, integrated into UniProtKB/Swiss-Prot.
DT 01-DEC-2001, sequence version 1.
DT 03-AUG-2022, entry version 138.
DE RecName: Full=UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase MurE homolog, chloroplastic {ECO:0000305};
DE Flags: Precursor;
GN Name=MURE {ECO:0000305};
GN OrderedLocusNames=Os10g0548900 {ECO:0000312|EMBL:BAF27145.1},
GN LOC_Os10g40130 {ECO:0000312|EMBL:AAP54910.1};
GN ORFNames=OSJNBa0082M15.18 {ECO:0000312|EMBL:AAK43503.1};
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12791992; DOI=10.1126/science.1083523;
RA Yu Y., Rambo T., Currie J., Saski C., Kim H.-R., Collura K., Thompson S.,
RA Simmons J., Yang T.-J., Nah G., Patel A.J., Thurmond S., Henry D.,
RA Oates R., Palmer M., Pries G., Gibson J., Anderson H., Paradkar M.,
RA Crane L., Dale J., Carver M.B., Wood T., Frisch D., Engler F.,
RA Soderlund C., Palmer L.E., Teytelman L., Nascimento L., De la Bastide M.,
RA Spiegel L., Ware D., O'Shaughnessy A., Dike S., Dedhia N., Preston R.,
RA Huang E., Ferraro K., Kuit K., Miller B., Zutavern T., Katzenberger F.,
RA Muller S., Balija V., Martienssen R.A., Stein L., Minx P., Johnson D.,
RA Cordum H., Mardis E., Cheng Z., Jiang J., Wilson R., McCombie W.R.,
RA Wing R.A., Yuan Q., Ouyang S., Liu J., Jones K.M., Gansberger K.,
RA Moffat K., Hill J., Tsitrin T., Overton L., Bera J., Kim M., Jin S.,
RA Tallon L., Ciecko A., Pai G., Van Aken S., Utterback T., Reidmuller S.,
RA Bormann J., Feldblyum T., Hsiao J., Zismann V., Blunt S., de Vazeille A.R.,
RA Shaffer T., Koo H., Suh B., Yang Q., Haas B., Peterson J., Pertea M.,
RA Volfovsky N., Wortman J., White O., Salzberg S.L., Fraser C.M., Buell C.R.,
RA Messing J., Song R., Fuks G., Llaca V., Kovchak S., Young S., Bowers J.E.,
RA Paterson A.H., Johns M.A., Mao L., Pan H., Dean R.A.;
RT "In-depth view of structure, activity, and evolution of rice chromosome
RT 10.";
RL Science 300:1566-1569(2003).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
CC -!- FUNCTION: Required for the activity of the plastid-encoded RNA
CC polymerase (PEP) and full expression of genes transcribed by PEP.
CC {ECO:0000250|UniProtKB:K7WCC7}.
CC -!- SUBUNIT: Component of the plastid-encoded plastid RNA polymerase (PEP)
CC complex. {ECO:0000250|UniProtKB:K7WCC7}.
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast {ECO:0000255}.
CC -!- SIMILARITY: Belongs to the MurCDEF family. MurE subfamily.
CC {ECO:0000305}.
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DR EMBL; AC020666; AAK43503.1; -; Genomic_DNA.
DR EMBL; DP000086; AAP54910.1; -; Genomic_DNA.
DR EMBL; AP008216; BAF27145.1; -; Genomic_DNA.
DR EMBL; AP014966; BAT11935.1; -; Genomic_DNA.
DR RefSeq; XP_015614047.1; XM_015758561.1.
DR AlphaFoldDB; Q94LU9; -.
DR SMR; Q94LU9; -.
DR STRING; 4530.OS10T0548900-01; -.
DR PaxDb; Q94LU9; -.
DR PRIDE; Q94LU9; -.
DR EnsemblPlants; Os10t0548900-01; Os10t0548900-01; Os10g0548900.
DR GeneID; 4349304; -.
DR Gramene; Os10t0548900-01; Os10t0548900-01; Os10g0548900.
DR KEGG; osa:4349304; -.
DR eggNOG; ENOG502QTHZ; Eukaryota.
DR InParanoid; Q94LU9; -.
DR OMA; FIPGRML; -.
DR OrthoDB; 1363473at2759; -.
DR PlantReactome; R-OSA-1119436; Peptidoglycan biosynthesis I.
DR PlantReactome; R-OSA-1119523; Tetrahydrofolate biosynthesis II.
DR PlantReactome; R-OSA-1119617; Folate polyglutamylation I.
DR Proteomes; UP000000763; Chromosome 10.
DR Proteomes; UP000059680; Chromosome 10.
DR ExpressionAtlas; Q94LU9; baseline and differential.
DR GO; GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
DR GO; GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR GO; GO:0051301; P:cell division; IEA:InterPro.
DR GO; GO:0010020; P:chloroplast fission; IEA:EnsemblPlants.
DR GO; GO:0008360; P:regulation of cell shape; IEA:InterPro.
DR Gene3D; 3.40.1190.10; -; 1.
DR Gene3D; 3.90.190.20; -; 1.
DR InterPro; IPR036565; Mur-like_cat_sf.
DR InterPro; IPR004101; Mur_ligase_C.
DR InterPro; IPR036615; Mur_ligase_C_dom_sf.
DR InterPro; IPR013221; Mur_ligase_cen.
DR InterPro; IPR035911; MurE/MurF_N.
DR InterPro; IPR005761; UDP-N-AcMur-Glu-dNH2Pim_ligase.
DR Pfam; PF02875; Mur_ligase_C; 1.
DR Pfam; PF08245; Mur_ligase_M; 1.
DR SUPFAM; SSF53244; SSF53244; 1.
DR SUPFAM; SSF53623; SSF53623; 1.
DR SUPFAM; SSF63418; SSF63418; 1.
DR TIGRFAMs; TIGR01085; murE; 1.
PE 3: Inferred from homology;
KW Chloroplast; Plastid; Reference proteome; Transcription;
KW Transcription regulation; Transit peptide.
FT TRANSIT 1..53
FT /note="Chloroplast"
FT /evidence="ECO:0000255"
FT CHAIN 54..757
FT /note="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-
FT diaminopimelate ligase MurE homolog, chloroplastic"
FT /id="PRO_0000441846"
FT REGION 1..112
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 126..152
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 172..195
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 14..29
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 42..84
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 757 AA; 82195 MW; 8EF030AFADE51F80 CRC64;
MATAPLAFHL PFPFPSASRP PPRLLPPSRR PPAARLAATR RFRPPTADDE PPEAAEDSSH
GLNRYDQLTR HVERARRRQQ AEQPEITPDH PLFSSPPSSG EAGSYDPDDE FFDEIDRAIA
EKREEFTRRG LIKPSAPAPS QPEEEDGLAD ELSPEEVIDL DEIRRLQGLS VVSLADEEDE
EANGGGGGVD YGDDGVPLDD DGEVFDVADE VGLEGARVRY PAFRMTLAEL LDESKLVPVA
VTGDQDVALA GVQRDASLVA AGDLYVCVGE EGLAGLTEAD KRGAVAVVAD QTVDIEGTLA
CRALVIVDDI TAALRMLPAC LYRRPSKDMA VIGVAGTDGV TTTAHLVRAM YEAMGVRTGM
VGVLGAYAFG NNKLDAQPDA SGDPIAVQRL MATMLYNGAE AALLEATTDG MPSSGVDSEI
DYDIAVLTNV RHAGDEAGMT YEEYMNSMAS LFSRMVDPER HRKVVNIDDP SAPFFAAQGG
QDVPVVTYSF ENKKADVHTL KYQLSLFETE VLVQTPHGIL EISSGLLGRD NIYNILASVA
VGVAVGAPLE DIVKGIEEVD AIPGRCELID EEQAFGVIVD HARTPESLSR LLDGVKELGP
RRIVTVIGCC GERERGKRPV MTKVAAEKSD VVMLTSDNPA NEDPLDILDD MLAGVGWTME
EYLKHGTNDY YPPLPNGHRI FLHDIRRVAV RAAVAMGEQG DVVVITGKGN DTYQIEVDKK
EFFDDREECR EALQYVDQLH RAGIDTSEFP WRLPESH
