ID   A13_VACCC               Reviewed;          70 AA.
AC   P20990;
DT   01-FEB-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1991, sequence version 1.
DT   23-FEB-2022, entry version 53.
DE   RecName: Full=Protein A13;
DE   AltName: Full=Protein P8;
GN   ORFNames=A13L;
OS   Vaccinia virus (strain Copenhagen) (VACV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Chitovirales; Poxviridae; Chordopoxvirinae; Orthopoxvirus; Vaccinia virus.
OX   NCBI_TaxID=10249;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=2219722; DOI=10.1016/0042-6822(90)90294-2;
RA   Goebel S.J., Johnson G.P., Perkus M.E., Davis S.W., Winslow J.P.,
RA   Paoletti E.;
RT   "The complete DNA sequence of vaccinia virus.";
RL   Virology 179:247-266(1990).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Goebel S.J., Johnson G.P., Perkus M.E., Davis S.W., Winslow J.P.,
RA   Paoletti E.;
RT   "Appendix to 'The complete DNA sequence of vaccinia virus'.";
RL   Virology 179:517-563(1990).
CC   -!- FUNCTION: Essential for the encapsidation of DNA into immature virions
CC       (IV) and the subsequent maturation of IV into mature virions (MV).
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Virion membrane {ECO:0000250}; Single-pass
CC       membrane protein {ECO:0000250}. Note=The mature virion is located in
CC       the cytoplasm of infected cells and is probably released by cell lysis.
CC       {ECO:0000250}.
CC   -!- INDUCTION: Expressed in the late phase of the viral replicative cycle.
CC   -!- PTM: Phosphorylated by a F10-independent mechanism. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the chordopoxvirinae A13 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; M35027; AAA48135.1; -; Genomic_DNA.
DR   PIR; F42518; F42518.
DR   SMR; P20990; -.
DR   Proteomes; UP000008269; Genome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0055036; C:virion membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR009236; Chordopox_A13L.
DR   Pfam; PF05961; Chordopox_A13L; 1.
PE   2: Evidence at transcript level;
KW   Late protein; Membrane; Phosphoprotein; Reference proteome; Transmembrane;
KW   Transmembrane helix; Virion.
FT   CHAIN           1..70
FT                   /note="Protein A13"
FT                   /id="PRO_0000099239"
FT   TRANSMEM        1..21
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        22..70
FT                   /note="Virion surface"
FT                   /evidence="ECO:0000255"
FT   REGION          30..50
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         40
FT                   /note="Phosphoserine; by host"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   70 AA;  7696 MW;  DB2F50B6E75F7955 CRC64;
     MIGILLLIGI CVAVTVAILY SMYNKIKNSQ NPNPSPNLNS PPPEPKNTKF VNNLEKDHIS
     SLYNLVKSSV