ID   MUTS_CHLPM              Reviewed;         874 AA.
AC   A4SFT1;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   15-MAY-2007, sequence version 1.
DT   03-AUG-2022, entry version 84.
DE   RecName: Full=DNA mismatch repair protein MutS {ECO:0000255|HAMAP-Rule:MF_00096};
GN   Name=mutS {ECO:0000255|HAMAP-Rule:MF_00096}; OrderedLocusNames=Cvib_1328;
OS   Chlorobium phaeovibrioides (strain DSM 265 / 1930) (Prosthecochloris
OS   vibrioformis (strain DSM 265)).
OC   Bacteria; Chlorobi; Chlorobia; Chlorobiales; Chlorobiaceae;
OC   Chlorobium/Pelodictyon group; Chlorobium.
OX   NCBI_TaxID=290318;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 265 / 1930;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Pitluck S., Schmutz J.,
RA   Larimer F., Land M., Hauser L., Mikhailova N., Li T., Overmann J.,
RA   Schuster S.C., Bryant D.A., Richardson P.;
RT   "Complete sequence of Prosthecochloris vibrioformis DSM 265.";
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: This protein is involved in the repair of mismatches in DNA.
CC       It is possible that it carries out the mismatch recognition step. This
CC       protein has a weak ATPase activity. {ECO:0000255|HAMAP-Rule:MF_00096}.
CC   -!- SIMILARITY: Belongs to the DNA mismatch repair MutS family.
CC       {ECO:0000255|HAMAP-Rule:MF_00096}.
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DR   EMBL; CP000607; ABP37340.1; -; Genomic_DNA.
DR   RefSeq; WP_011890563.1; NC_009337.1.
DR   AlphaFoldDB; A4SFT1; -.
DR   SMR; A4SFT1; -.
DR   STRING; 290318.Cvib_1328; -.
DR   EnsemblBacteria; ABP37340; ABP37340; Cvib_1328.
DR   KEGG; pvi:Cvib_1328; -.
DR   eggNOG; COG0249; Bacteria.
DR   HOGENOM; CLU_002472_4_0_10; -.
DR   OMA; TPMMAQY; -.
DR   OrthoDB; 15991at2; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR   GO; GO:0003684; F:damaged DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR   GO; GO:0006298; P:mismatch repair; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.30.420.110; -; 1.
DR   Gene3D; 3.40.1170.10; -; 1.
DR   Gene3D; 3.40.50.300; -; 1.
DR   HAMAP; MF_00096; MutS; 1.
DR   InterPro; IPR005748; DNA_mismatch_repair_MutS.
DR   InterPro; IPR007695; DNA_mismatch_repair_MutS-lik_N.
DR   InterPro; IPR017261; DNA_mismatch_repair_MutS/MSH.
DR   InterPro; IPR000432; DNA_mismatch_repair_MutS_C.
DR   InterPro; IPR007861; DNA_mismatch_repair_MutS_clamp.
DR   InterPro; IPR007696; DNA_mismatch_repair_MutS_core.
DR   InterPro; IPR016151; DNA_mismatch_repair_MutS_N.
DR   InterPro; IPR036187; DNA_mismatch_repair_MutS_sf.
DR   InterPro; IPR007860; DNA_mmatch_repair_MutS_con_dom.
DR   InterPro; IPR036678; MutS_con_dom_sf.
DR   InterPro; IPR045076; MutS_family.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR11361; PTHR11361; 1.
DR   Pfam; PF01624; MutS_I; 1.
DR   Pfam; PF05188; MutS_II; 1.
DR   Pfam; PF05192; MutS_III; 1.
DR   Pfam; PF05190; MutS_IV; 1.
DR   Pfam; PF00488; MutS_V; 1.
DR   PIRSF; PIRSF037677; DNA_mis_repair_Msh6; 1.
DR   SMART; SM00534; MUTSac; 1.
DR   SMART; SM00533; MUTSd; 1.
DR   SUPFAM; SSF48334; SSF48334; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   SUPFAM; SSF53150; SSF53150; 1.
DR   SUPFAM; SSF55271; SSF55271; 1.
DR   TIGRFAMs; TIGR01070; mutS1; 1.
DR   PROSITE; PS00486; DNA_MISMATCH_REPAIR_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding; DNA damage; DNA repair; DNA-binding; Nucleotide-binding.
FT   CHAIN           1..874
FT                   /note="DNA mismatch repair protein MutS"
FT                   /id="PRO_0000335202"
FT   BINDING         630..637
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00096"
SQ   SEQUENCE   874 AA;  97458 MW;  C64C0592058A6D26 CRC64;
     MAAKKSGASK ELSPMMRQYL DVKKQYADYL LLFRVGDFYE TFFDDAATIS AAVNIVLTRR
     SNGSAPDIPM AGFPYHASEG YIARLVRKGF KVAVCEQVED PAEAKGIVKR EITEIVTPGV
     TYSDSILEDR HNNYLAAVAF LKEGRTPVAG IAYLDVTTAE FRIASLPPHS LRDTILSLGP
     AELLVSSSEK SRLEDLVRGY ATGMLVTGLD DWMFSEEQAE TVLSRQFRTH SLKGFGIEGN
     RAGRVAAGVV LQYLDETRQS RRAYITRISE MQGGEFMTLD LQTKRNLEIV SSMQDGSPHG
     SLLQVMDRTV NPMGARLIRR WLQRPLRVAE AIAERHDGVE ELLQSSELSE GVRCSLSEIN
     DLERSLARIA TFRTSPREVL QMGRSLAVFP QLRDLLLPAL SARLRSLAAV LQPLPELVSE
     IERSVDPECG ATVRDGGYIR SGCNDELDEL RSVSSMAKER LMDIQREERE KTGISSLKVQ
     YNRVFGYYIE ISRANLDRVP EGYMKKQTLV NAERYTIPAL KAYEEKILNA EERSLRLEAE
     IFQALCASIA ERAASIQESA LAIAEIDTLA SFALSAKEYG YCKPEMKEHE GLLITEGRHP
     VLERIMKPDE PFVKNDCHFD GQQRMLMITG PNMAGKSSYL RQTGLIVLLA QAGSFVPAER
     AEIGMVDRIF TRVGASDNLA SGESTFLVEM NEAASILNNA TSSSLILLDE IGRGTSTFDG
     MSIAWSMSEY IITRLGARTL FATHYHELSE LEERLPGVVN YNATVVESGE RVIFLRKIVR
     GSTDNSYGIE VARMAGMPNE VIERAREIMS GLERKDVSFA DRSFSVQENM QISLFDEVDS
     RLKTALQDLD LERLTPIEAL LELEKLQKLL RGHS