ID   A13_VARV                Reviewed;          68 AA.
AC   P0DSW2; P33838;
DT   16-OCT-2019, integrated into UniProtKB/Swiss-Prot.
DT   16-OCT-2019, sequence version 1.
DT   23-FEB-2022, entry version 11.
DE   RecName: Full=Virion membrane protein A13;
GN   ORFNames=A13L;
OS   Variola virus.
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Chitovirales; Poxviridae; Chordopoxvirinae; Orthopoxvirus.
OX   NCBI_TaxID=10255;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=Bangladesh-1975;
RX   PubMed=8264798; DOI=10.1038/366748a0;
RA   Massung R.F., Esposito J.J., Liu L.I., Qi J., Utterback T.R., Knight J.C.,
RA   Aubin L., Yuran T.E., Parsons J.M., Loparev V.N., Selivanov N.A.,
RA   Cavallaro K.F., Kerlavage A.R., Mahy B.W.J., Venter J.C.;
RT   "Potential virulence determinants in terminal regions of variola smallpox
RT   virus genome.";
RL   Nature 366:748-751(1993).
CC   -!- FUNCTION: Essential for the encapsidation of DNA into immature virions
CC       (IV) and the subsequent maturation of IV into mature virions (MV).
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Virion membrane {ECO:0000250}; Single-pass
CC       membrane protein {ECO:0000250}. Note=The mature virion is located in
CC       the cytoplasm of infected cells and is probably released by cell lysis.
CC       {ECO:0000250}.
CC   -!- INDUCTION: Expressed in the late phase of the viral replicative cycle.
CC   -!- SIMILARITY: Belongs to the chordopoxvirinae A13 family. {ECO:0000305}.
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DR   EMBL; L22579; AAA60865.1; -; Genomic_DNA.
DR   PIR; T28555; T28555.
DR   RefSeq; NP_042161.1; NC_001611.1.
DR   SMR; P0DSW2; -.
DR   GeneID; 1486488; -.
DR   KEGG; vg:1486488; -.
DR   Proteomes; UP000119805; Genome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0055036; C:virion membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR009236; Chordopox_A13L.
DR   Pfam; PF05961; Chordopox_A13L; 1.
PE   2: Evidence at transcript level;
KW   Late protein; Membrane; Transmembrane; Transmembrane helix; Virion.
FT   CHAIN           1..68
FT                   /note="Virion membrane protein A13"
FT                   /id="PRO_0000448152"
FT   TRANSMEM        1..21
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        22..68
FT                   /note="Virion surface"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   68 AA;  7541 MW;  15BB909719033147 CRC64;
     MIGILLLIGI CVAVTVAILY AMYNKIKNSQ NPSPNVNLPP PETRNTRFVN NLEKDHISSL
     YNLVKSSV