ID   MUTS_PSEPG              Reviewed;         861 AA.
AC   B0KSD2;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   20-MAY-2008, sequence version 2.
DT   03-AUG-2022, entry version 71.
DE   RecName: Full=DNA mismatch repair protein MutS {ECO:0000255|HAMAP-Rule:MF_00096};
GN   Name=mutS {ECO:0000255|HAMAP-Rule:MF_00096};
GN   OrderedLocusNames=PputGB1_1179;
OS   Pseudomonas putida (strain GB-1).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=76869;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GB-1;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E.,
RA   Tice H., Pitluck S., Bruce D., Goodwin L., Chertkov O., Brettin T.,
RA   Detter J.C., Han C., Kuske C.R., Schmutz J., Larimer F., Land M.,
RA   Hauser L., Kyrpides N., Kim E., McCarthy J.K., Richardson P.;
RT   "Complete sequence of Pseudomonas putida GB-1.";
RL   Submitted (JAN-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: This protein is involved in the repair of mismatches in DNA.
CC       It is possible that it carries out the mismatch recognition step. This
CC       protein has a weak ATPase activity. {ECO:0000255|HAMAP-Rule:MF_00096}.
CC   -!- SIMILARITY: Belongs to the DNA mismatch repair MutS family.
CC       {ECO:0000255|HAMAP-Rule:MF_00096}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=ABY97087.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; CP000926; ABY97087.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_041166643.1; NC_010322.1.
DR   AlphaFoldDB; B0KSD2; -.
DR   SMR; B0KSD2; -.
DR   STRING; 76869.PputGB1_1179; -.
DR   EnsemblBacteria; ABY97087; ABY97087; PputGB1_1179.
DR   KEGG; ppg:PputGB1_1179; -.
DR   eggNOG; COG0249; Bacteria.
DR   HOGENOM; CLU_002472_4_0_6; -.
DR   Proteomes; UP000002157; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR   GO; GO:0003684; F:damaged DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR   GO; GO:0006298; P:mismatch repair; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.30.420.110; -; 1.
DR   Gene3D; 3.40.1170.10; -; 1.
DR   Gene3D; 3.40.50.300; -; 1.
DR   HAMAP; MF_00096; MutS; 1.
DR   InterPro; IPR005748; DNA_mismatch_repair_MutS.
DR   InterPro; IPR007695; DNA_mismatch_repair_MutS-lik_N.
DR   InterPro; IPR017261; DNA_mismatch_repair_MutS/MSH.
DR   InterPro; IPR000432; DNA_mismatch_repair_MutS_C.
DR   InterPro; IPR007861; DNA_mismatch_repair_MutS_clamp.
DR   InterPro; IPR007696; DNA_mismatch_repair_MutS_core.
DR   InterPro; IPR016151; DNA_mismatch_repair_MutS_N.
DR   InterPro; IPR036187; DNA_mismatch_repair_MutS_sf.
DR   InterPro; IPR007860; DNA_mmatch_repair_MutS_con_dom.
DR   InterPro; IPR036678; MutS_con_dom_sf.
DR   InterPro; IPR045076; MutS_family.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR11361; PTHR11361; 1.
DR   Pfam; PF01624; MutS_I; 1.
DR   Pfam; PF05188; MutS_II; 1.
DR   Pfam; PF05192; MutS_III; 1.
DR   Pfam; PF05190; MutS_IV; 1.
DR   Pfam; PF00488; MutS_V; 1.
DR   PIRSF; PIRSF037677; DNA_mis_repair_Msh6; 1.
DR   SMART; SM00534; MUTSac; 1.
DR   SMART; SM00533; MUTSd; 1.
DR   SUPFAM; SSF48334; SSF48334; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   SUPFAM; SSF53150; SSF53150; 1.
DR   SUPFAM; SSF55271; SSF55271; 1.
DR   TIGRFAMs; TIGR01070; mutS1; 1.
DR   PROSITE; PS00486; DNA_MISMATCH_REPAIR_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding; DNA damage; DNA repair; DNA-binding; Nucleotide-binding.
FT   CHAIN           1..861
FT                   /note="DNA mismatch repair protein MutS"
FT                   /id="PRO_0000335204"
FT   REGION          799..822
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         617..624
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00096"
SQ   SEQUENCE   861 AA;  95531 MW;  D1C69269946058D4 CRC64;
     MNKAISDFTA HTPMMQQYWK LKNQHPDQLM FYRMGDFYEI FYEDAKKAAK LLDITLTARG
     QSAGQSIPMC GIPFHSLEGY LAKLVKLGES VVICEQIGDP ATSKGPVERQ VVRIITPGTV
     SDEALLDERR DNLIAALLGD ERLFGLAVLD ITSGNFSVQE IKGWENLLAE LERLNPVELL
     IPDDWPRDLP AEKRPGARRR APWDFDRDSA RKALCQQFAT KDLKGFGCDK LTLAIGAAGC
     LLTYAKETQR TALPHLRSLR HERLDDTVIL DGASRRNLEL DINLAGGRDN TLQSVIDRCQ
     TAMASRLLSR WLNRPLRDLK VLQARQDSIR CLLDSYRFEK LQPQLKEIGD IERILARIGL
     RNARPRDLAR LRDALGALPE LQNAMTELEA PHLARLAAIT GTYPELASLL ERAIIDNPPA
     VIRDGGVLKA GYDNELDDLL AISENAGQFL IDLEAREKAR TGLANLKVGY NRVHGYFIEL
     PTKQAEQAPG DYIRRQTLKG AERFITPELK AFEDKALSAK SRALAREKML YDALLETLIS
     HLAPLQDSAA ALAELDVLSN LAERALNLDL NCPRFVDEPC LRIVQGRHPV VEQVLTTPFV
     ANDLGLDNST RMLIITGPNM GGKSTYMRQT ALIVLLAHIG SFVPAASCEL SLVDRIFTRI
     GSSDDLAGGR STFMVEMSET ANILHNATDR SLVLMDEVGR GTSTFDGLSL AWAAAERLAQ
     LRAYTLFATH YFELTVLPES EPLVANVHLN ATEHNERIVF LHHVLPGPAS QSYGLAVAQL
     AGVPTVVIQR AREHLGRLET TSLPHEQPPA AKAKDAPQVP HQSDLFASLP HPAIEKLGKL
     QLDDMTPRQA IEMLYQLKNL L