ID   MUTT_STRAM              Reviewed;         154 AA.
AC   P32091;
DT   01-OCT-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1993, sequence version 1.
DT   03-AUG-2022, entry version 72.
DE   RecName: Full=MutT-like protein;
DE   AltName: Full=ORF154;
OS   Streptomyces ambofaciens.
OG   Plasmid pSAM2.
OC   Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
OC   Streptomyces.
OX   NCBI_TaxID=1889;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 23877 / 3486 / DSM 40053 / JCM 4204 / NBRC 12836 / NRRL B-2516;
RX   PubMed=7934842; DOI=10.1111/j.1365-2958.1993.tb00950.x;
RA   Hagege J., Pernodet J.L., Friedmann A., Guerineau M.;
RT   "Mode and origin of replication of pSAM2, a conjugative integrating element
RT   of Streptomyces ambofaciens.";
RL   Mol. Microbiol. 10:799-812(1993).
CC   -!- SIMILARITY: Belongs to the Nudix hydrolase family. {ECO:0000305}.
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DR   EMBL; Z19590; CAA79638.1; -; Genomic_DNA.
DR   PIR; S39873; S39873.
DR   AlphaFoldDB; P32091; -.
DR   SMR; P32091; -.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   InterPro; IPR020476; Nudix_hydrolase.
DR   InterPro; IPR015797; NUDIX_hydrolase-like_dom_sf.
DR   InterPro; IPR020084; NUDIX_hydrolase_CS.
DR   InterPro; IPR000086; NUDIX_hydrolase_dom.
DR   Pfam; PF00293; NUDIX; 1.
DR   PRINTS; PR00502; NUDIXFAMILY.
DR   SUPFAM; SSF55811; SSF55811; 1.
DR   PROSITE; PS51462; NUDIX; 1.
DR   PROSITE; PS00893; NUDIX_BOX; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Magnesium; Metal-binding; Plasmid.
FT   CHAIN           1..154
FT                   /note="MutT-like protein"
FT                   /id="PRO_0000056951"
FT   DOMAIN          15..136
FT                   /note="Nudix hydrolase"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00794"
FT   MOTIF           48..69
FT                   /note="Nudix box"
FT   BINDING         48
FT                   /ligand="Mg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:18420"
FT                   /evidence="ECO:0000250"
FT   BINDING         63
FT                   /ligand="Mg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:18420"
FT                   /evidence="ECO:0000250"
FT   BINDING         66
FT                   /ligand="Mg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:18420"
FT                   /evidence="ECO:0000250"
FT   BINDING         67
FT                   /ligand="Mg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:18420"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   154 AA;  16689 MW;  8EC2EE99D272D656 CRC64;
     MLLYMSQPQE ATSPPLHSVS VAGVVVREDG RLLAIRRADN GTWELPGGVL ELDETPETGV
     AREVWEETGI RVEVDELTGV YKNTTRGIVA LVFRCKPSGG VERTSSESTA VSWLTPDEVS
     ERMAEVYAIR LLDALDGAGP HVRSHDGKHL IPAG