ID   MVHG_METTM              Reviewed;         308 AA.
AC   P60239; D9PXZ9;
DT   16-JAN-2004, integrated into UniProtKB/Swiss-Prot.
DT   30-NOV-2010, sequence version 2.
DT   25-MAY-2022, entry version 62.
DE   RecName: Full=F420-non-reducing hydrogenase subunit G;
DE            EC=1.12.99.-;
DE   AltName: Full=Methyl viologen-reducing hydrogenase subunit gamma;
DE            Short=MVH subunit G;
GN   Name=mvhG; OrderedLocusNames=MTBMA_c15180;
OS   Methanothermobacter marburgensis (strain ATCC BAA-927 / DSM 2133 / JCM
OS   14651 / NBRC 100331 / OCM 82 / Marburg) (Methanobacterium
OS   thermoautotrophicum).
OC   Archaea; Euryarchaeota; Methanomada group; Methanobacteria;
OC   Methanobacteriales; Methanobacteriaceae; Methanothermobacter.
OX   NCBI_TaxID=79929;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-927 / DSM 2133 / JCM 14651 / NBRC 100331 / OCM 82 /
RC   Marburg;
RX   PubMed=20802048; DOI=10.1128/jb.00844-10;
RA   Liesegang H., Kaster A.K., Wiezer A., Goenrich M., Wollherr A., Seedorf H.,
RA   Gottschalk G., Thauer R.K.;
RT   "Complete genome sequence of Methanothermobacter marburgensis, a
RT   methanoarchaeon model organism.";
RL   J. Bacteriol. 192:5850-5851(2010).
RN   [2]
RP   PROTEIN SEQUENCE OF 2-21, SUBUNIT, AND ASSOCIATION WITH HETERODISULFIDE
RP   REDUCTASE.
RC   STRAIN=ATCC BAA-927 / DSM 2133 / JCM 14651 / NBRC 100331 / OCM 82 /
RC   Marburg;
RX   PubMed=8119281; DOI=10.1111/j.1432-1033.1994.tb18608.x;
RA   Setzke E., Hedderich R., Heiden S., Thauer R.K.;
RT   "H2: heterodisulfide oxidoreductase complex from Methanobacterium
RT   thermoautotrophicum. Composition and properties.";
RL   Eur. J. Biochem. 220:139-148(1994).
RN   [3]
RP   FUNCTION, AND ASSOCIATION WITH HETERODISULFIDE REDUCTASE.
RC   STRAIN=ATCC BAA-927 / DSM 2133 / JCM 14651 / NBRC 100331 / OCM 82 /
RC   Marburg;
RX   PubMed=12856108; DOI=10.1007/s00203-003-0577-9;
RA   Stojanowic A., Mander G.J., Duin E.C., Hedderich R.;
RT   "Physiological role of the F420-non-reducing hydrogenase (Mvh) from
RT   Methanothermobacter marburgensis.";
RL   Arch. Microbiol. 180:194-203(2003).
CC   -!- FUNCTION: Part of a complex that provides reducing equivalents for
CC       heterodisulfide reductase. {ECO:0000269|PubMed:12856108}.
CC   -!- SUBUNIT: The F420-non-reducing hydrogenase is composed of three
CC       subunits; MvhA, MvhD and MvhG. It forms a complex with the
CC       heterodisulfide reductase (hdr). {ECO:0000269|PubMed:8119281}.
CC   -!- SIMILARITY: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit
CC       family. {ECO:0000305}.
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DR   EMBL; CP001710; ADL59097.1; -; Genomic_DNA.
DR   RefSeq; WP_013296308.1; NC_014408.1.
DR   AlphaFoldDB; P60239; -.
DR   SMR; P60239; -.
DR   DIP; DIP-59605N; -.
DR   IntAct; P60239; 1.
DR   STRING; 79929.MTBMA_c15180; -.
DR   TCDB; 3.D.7.2.4; the h2:heterodisulfide oxidoreductase (hho) family.
DR   EnsemblBacteria; ADL59097; ADL59097; MTBMA_c15180.
DR   GeneID; 9705227; -.
DR   KEGG; mmg:MTBMA_c15180; -.
DR   PATRIC; fig|79929.8.peg.1471; -.
DR   HOGENOM; CLU_053270_0_0_2; -.
DR   OMA; VKIATTW; -.
DR   OrthoDB; 44934at2157; -.
DR   Proteomes; UP000000345; Chromosome.
DR   GO; GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.700; -; 1.
DR   InterPro; IPR006137; NADH_UbQ_OxRdtase-like_20kDa.
DR   InterPro; IPR037024; NiFe_Hase_small_N_sf.
DR   Pfam; PF01058; Oxidored_q6; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Oxidoreductase.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000269|PubMed:8119281"
FT   CHAIN           2..308
FT                   /note="F420-non-reducing hydrogenase subunit G"
FT                   /id="PRO_0000204358"
FT   CONFLICT        15
FT                   /note="Missing (in Ref. 2; AA sequence)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        21
FT                   /note="S -> I (in Ref. 2; AA sequence)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   308 AA;  33755 MW;  5D15ECA78B9F3EDB CRC64;
     MAEKIKIGTM WLGGCSGCHL SIADFHEKLL DVMEHADFEF SPVLMDTKYD EIPELDVVVI
     EGGIVNDENR EFAEELREKA KFVISYGTCA VYGGIPGLRN LWDKDEVIEE AYINSITTPN
     EEGVIPSEDV PHLEGRVKPL GEVIDVDFEV PGCPPRSDVA AEVVMALLKG EEIELPSTNL
     CEVCPREKPP EGLAMDFIKR QFEVGKPEDD LCLIPQGLIC MGPATVSICG AECPSIAIPC
     RGCYGPTARV EDQGAKMISA IASDYKVEED KTVDPEEVAE QLDDIVGTFY TFTLPAALIP
     MKIKKEGK