ID   MVP_AMVLE               Reviewed;         300 AA.
AC   P03595;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1988, sequence version 1.
DT   03-AUG-2022, entry version 67.
DE   RecName: Full=Movement protein;
DE            Short=MP;
DE   AltName: Full=Protein 3A;
GN   ORFNames=ORF3a;
OS   Alfalfa mosaic virus (strain 425 / isolate Leiden).
OC   Viruses; Riboviria; Orthornavirae; Kitrinoviricota; Alsuviricetes;
OC   Martellivirales; Bromoviridae; Alfamovirus.
OX   NCBI_TaxID=12322;
OH   NCBI_TaxID=4045; Apium graveolens (Celery).
OH   NCBI_TaxID=83862; Astragalus glycyphyllos (Wild liquorice).
OH   NCBI_TaxID=4072; Capsicum annuum (Capsicum pepper).
OH   NCBI_TaxID=41386; Caryopteris incana.
OH   NCBI_TaxID=3827; Cicer arietinum (Chickpea) (Garbanzo).
OH   NCBI_TaxID=3847; Glycine max (Soybean) (Glycine hispida).
OH   NCBI_TaxID=35936; Lablab purpureus (Hyacinth bean) (Dolichos lablab).
OH   NCBI_TaxID=4236; Lactuca sativa (Garden lettuce).
OH   NCBI_TaxID=3864; Lens culinaris (Lentil) (Cicer lens).
OH   NCBI_TaxID=3869; Lupinus.
OH   NCBI_TaxID=145753; Malva parviflora (Little mallow) (Cheeseweed mallow).
OH   NCBI_TaxID=3879; Medicago sativa (Alfalfa).
OH   NCBI_TaxID=4097; Nicotiana tabacum (Common tobacco).
OH   NCBI_TaxID=3885; Phaseolus vulgaris (Kidney bean) (French bean).
OH   NCBI_TaxID=23113; Philadelphus.
OH   NCBI_TaxID=3888; Pisum sativum (Garden pea).
OH   NCBI_TaxID=4081; Solanum lycopersicum (Tomato) (Lycopersicon esculentum).
OH   NCBI_TaxID=4113; Solanum tuberosum (Potato).
OH   NCBI_TaxID=157662; Teramnus repens.
OH   NCBI_TaxID=60916; Trifolium incarnatum (Crimson clover).
OH   NCBI_TaxID=85293; Viburnum opulus (High-bush cranberry).
OH   NCBI_TaxID=3916; Vigna radiata var. radiata (Mung bean) (Phaseolus aureus).
OH   NCBI_TaxID=3917; Vigna unguiculata (Cowpea).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RA   Langereis K., Mugnier M.-A., Cornelissen B.J.C., Pinck L., Bol J.F.;
RT   "Variable repeats and poly(A)-stretches in the leader sequence of alfalfa
RT   mosaic virus RNA 3.";
RL   Virology 154:409-414(1986).
RN   [2]
RP   SUBCELLULAR LOCATION.
RX   PubMed=9267012; DOI=10.1099/0022-1317-78-8-2089;
RA   Kasteel D.T., van der Wel N.N., Jansen K.A., Goldbach R.W., van Lent J.W.;
RT   "Tubule-forming capacity of the movement proteins of alfalfa mosaic virus
RT   and brome mosaic virus.";
RL   J. Gen. Virol. 78:2089-2093(1997).
CC   -!- FUNCTION: Transports viral genome to neighboring plant cells directly
CC       through plasmosdesmata, without any budding. The movement protein
CC       allows efficient cell to cell propagation, by bypassing the host cell
CC       wall barrier. Acts by forming a tubular structure at the host
CC       plasmodesmata, enlarging it enough to allow free passage of virion
CC       capsids.
CC   -!- SUBCELLULAR LOCATION: Host cell junction, host plasmodesma
CC       {ECO:0000269|PubMed:9267012}. Note=Assembles into long tubular
CC       structures at the surface of the infected protoplast.
CC   -!- SIMILARITY: Belongs to the alfamovirus movement protein family.
CC       {ECO:0000305}.
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DR   EMBL; K03542; AAA46295.1; -; Genomic_RNA.
DR   Proteomes; UP000000358; Genome.
DR   GO; GO:0044219; C:host cell plasmodesma; IEA:UniProtKB-SubCell.
DR   GO; GO:0046740; P:transport of virus in host, cell to cell; IEA:UniProtKB-KW.
DR   InterPro; IPR002538; Bromo_MP.
DR   Pfam; PF01573; Bromo_MP; 1.
PE   3: Inferred from homology;
KW   Host cell junction; Reference proteome; Transport; Viral movement protein.
FT   CHAIN           1..300
FT                   /note="Movement protein"
FT                   /id="PRO_0000083226"
SQ   SEQUENCE   300 AA;  32374 MW;  78DBBC79406C0360 CRC64;
     MENTKTNASS SGMSSSSSFS VSYAEEMLLA DEVSKTNSMS ILGPNQLKLC TQLVLSNGAA
     PVVLSLVSKE KKSILNRMLP KIGQRMYVHH SAIYLLYMPN ILKSSSGSIT LKLFNEATGE
     LVDVDTDHDA TQACIFAGRY PRSILAKDAA KGHDLKLVVH AVASTNMNSA VGVLYPIWED
     ELSRKQILER GADFLKFPIA KTEPVRDLLN AGKLTDFVLN RTRLGVGSKS DPSPVLLEPR
     AKIAGKAKTL FIPEGPSVPS TTINGMAPTV RIDAGSPKGL GVPKGFTYES FIKDEILPDH