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MVP_CAMVD
ID   MVP_CAMVD               Reviewed;         327 AA.
AC   P03547;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   21-JUL-1986, sequence version 1.
DT   25-MAY-2022, entry version 70.
DE   RecName: Full=Movement protein;
DE            Short=Mov;
DE   AltName: Full=Cell-to-cell transport protein;
GN   ORFNames=ORF I;
OS   Cauliflower mosaic virus (strain D/H) (CaMV).
OC   Viruses; Riboviria; Pararnavirae; Artverviricota; Revtraviricetes;
OC   Ortervirales; Caulimoviridae; Caulimovirus.
OX   NCBI_TaxID=10645;
OH   NCBI_TaxID=3702; Arabidopsis thaliana (Mouse-ear cress).
OH   NCBI_TaxID=3705; Brassica.
OH   NCBI_TaxID=3725; Raphanus.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=7152260; DOI=10.1016/0378-1119(82)90013-0;
RA   Balazs E., Guilley H., Jonard G., Richards K.;
RT   "Nucleotide sequence of DNA from an altered-virulence isolate D/H of the
RT   cauliflower mosaic virus.";
RL   Gene 19:239-249(1982).
CC   -!- FUNCTION: Transports viral genome to neighboring plant cells directly
CC       through plasmosdesmata, without any budding. The movement protein
CC       allows efficient cell to cell propagation, by bypassing the host cell
CC       wall barrier. Acts by forming tubules structures that increase the size
CC       exclusion limit (SEL) of plasmodesmata, thereby allowing viral
CC       ribonucleocapsids to spread directly to neighboring cells (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Homotrimer, through the coiled-coil domain. Interacts with
CC       VAP. May interact (via N-terminus) with host prenylated Rab acceptor
CC       protein 1D (PRA1D). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Host cell junction, host plasmodesma.
CC       Note=Assembles in tubules that are embedded within modified
CC       plasmodesmata.
CC   -!- SIMILARITY: Belongs to the caulimoviridae movement protein family.
CC       {ECO:0000305}.
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DR   EMBL; M10376; AAA46345.1; -; Genomic_DNA.
DR   Proteomes; UP000008439; Genome.
DR   GO; GO:0044219; C:host cell plasmodesma; IEA:UniProtKB-SubCell.
DR   GO; GO:0046740; P:transport of virus in host, cell to cell; IEA:UniProtKB-KW.
DR   InterPro; IPR028919; Viral_movement.
DR   Pfam; PF01107; MP; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Host cell junction; Host-virus interaction; Transport;
KW   Viral movement protein.
FT   CHAIN           1..327
FT                   /note="Movement protein"
FT                   /id="PRO_0000222059"
FT   COILED          297..327
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   327 AA;  36885 MW;  49CB6E1EF8CABACC CRC64;
     MDLYPEENTQ SEQSQNSENN MQIFKSETSD GFSSDLKISN DQLKNISKTQ LTLEKEKIFK
     MPNVLSQVMK KAFSRKNEIL YCVSTKELSV DIHDATGKVY LPLITKEEIN KRLSSLKPEV
     RRTMSMVHLG AVKILLKAQF RNGIDTPIKI ALIDDRINSR RDCLLGAAKG NLAYGKFMFT
     VYPKFGISLN TQRLNQTLSL IHDFENKNLM NKGDKVMTIT YIVGYALTNS HHSIDYQSNA
     TIELEDVFQE IGNIQQSEFC TIQNDECNWA IDIAQNKALL GAKTKTQIGN SLQIGNIASS
     SSTENELARV SQNIDLLKNK LKEICGE
 
 
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