MVP_CAMVE
ID MVP_CAMVE Reviewed; 327 AA.
AC Q02968;
DT 01-JUL-1993, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1995, sequence version 2.
DT 07-OCT-2020, entry version 60.
DE RecName: Full=Movement protein;
DE Short=Mov;
DE AltName: Full=Cell-to-cell transport protein;
GN ORFNames=ORF I;
OS Cauliflower mosaic virus (strain BBC) (CaMV).
OC Viruses; Riboviria; Pararnavirae; Artverviricota; Revtraviricetes;
OC Ortervirales; Caulimoviridae; Caulimovirus.
OX NCBI_TaxID=31556;
OH NCBI_TaxID=3702; Arabidopsis thaliana (Mouse-ear cress).
OH NCBI_TaxID=3705; Brassica.
OH NCBI_TaxID=3725; Raphanus.
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=8428667; DOI=10.1016/0378-1119(93)90133-n;
RA Chenault K.D., Melcher U.K.;
RT "The complete nucleotide sequence of cauliflower mosaic virus isolate
RT BBC.";
RL Gene 123:255-257(1993).
CC -!- FUNCTION: Transports viral genome to neighboring plant cells directly
CC through plasmosdesmata, without any budding. The movement protein
CC allows efficient cell to cell propagation, by bypassing the host cell
CC wall barrier. Acts by forming tubules structures that increase the size
CC exclusion limit (SEL) of plasmodesmata, thereby allowing viral
CC ribonucleocapsids to spread directly to neighboring cells (By
CC similarity). {ECO:0000250}.
CC -!- SUBUNIT: Homotrimer, through the coiled-coil domain. Interacts with
CC VAP. May interact (via N-terminus) with host prenylated Rab acceptor
CC protein 1D (PRA1D). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Host cell junction, host plasmodesma.
CC Note=Assembles in tubules that are embedded within modified
CC plasmodesmata.
CC -!- SIMILARITY: Belongs to the caulimoviridae movement protein family.
CC {ECO:0000305}.
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DR EMBL; M90542; AAA62371.1; -; Genomic_DNA.
DR Proteomes; UP000008440; Genome.
DR GO; GO:0044219; C:host cell plasmodesma; IEA:UniProtKB-SubCell.
DR GO; GO:0046740; P:transport of virus in host, cell to cell; IEA:UniProtKB-KW.
DR InterPro; IPR028919; Viral_movement.
DR Pfam; PF01107; MP; 1.
PE 3: Inferred from homology;
KW Coiled coil; Host cell junction; Host-virus interaction; Transport;
KW Viral movement protein.
FT CHAIN 1..327
FT /note="Movement protein"
FT /id="PRO_0000222060"
FT COILED 297..327
FT /evidence="ECO:0000250"
SQ SEQUENCE 327 AA; 36943 MW; C0C8EB985F46CCF9 CRC64;
MDLYPEENTQ SEQSQNSENN MQIFKSENSD GFSSDLMISN DQLKNISKTQ LTLEKEKIFK
MPNVLSQVMK RAFSRKNEIL YCVSTKELSV DIHDATGKVY LPLITREEIN KRLSSLKPEV
RKTMSMVHLG AVKILLKAQF RNGIDTPIKI ALIDDRINSR RDCLLGAAKG NLAYGKFMFT
VYPKFGISLN TQRLNQTLSL IHDFENKNLM NKGDKVMTIT YMVGYALTNS HHSIDYQSNA
TIELEDVFQE IGNVHESDFC TIQNDECNWA IDIAQNKALL GAKTKSQIGN NLQIGNSASS
SNTENELARV SQNIDLLKNK LKEICGE