MVP_CAMVW
ID MVP_CAMVW Reviewed; 327 AA.
AC Q01089;
DT 01-APR-1993, integrated into UniProtKB/Swiss-Prot.
DT 01-APR-1993, sequence version 1.
DT 07-OCT-2020, entry version 55.
DE RecName: Full=Movement protein;
DE Short=Mov;
DE AltName: Full=Cell-to-cell transport protein;
GN ORFNames=ORF I;
OS Cauliflower mosaic virus (strain W260) (CaMV).
OC Viruses; Riboviria; Pararnavirae; Artverviricota; Revtraviricetes;
OC Ortervirales; Caulimoviridae; Caulimovirus.
OX NCBI_TaxID=31558;
OH NCBI_TaxID=3702; Arabidopsis thaliana (Mouse-ear cress).
OH NCBI_TaxID=3705; Brassica.
OH NCBI_TaxID=3725; Raphanus.
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=1519358; DOI=10.1016/0042-6822(92)90915-c;
RA Qiu S.G., Schoelz J.E.;
RT "Three regions of cauliflower mosaic virus strain W260 are involved in
RT systemic infection of solanaceous hosts.";
RL Virology 190:773-782(1992).
CC -!- FUNCTION: Transports viral genome to neighboring plant cells directly
CC through plasmosdesmata, without any budding. The movement protein
CC allows efficient cell to cell propagation, by bypassing the host cell
CC wall barrier. Acts by forming tubules structures that increase the size
CC exclusion limit (SEL) of plasmodesmata, thereby allowing viral
CC ribonucleocapsids to spread directly to neighboring cells (By
CC similarity). {ECO:0000250}.
CC -!- SUBUNIT: Homotrimer, through the coiled-coil domain. Interacts with
CC VAP. May interact (via N-terminus) with host prenylated Rab acceptor
CC protein 1D (PRA1D). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Host cell junction, host plasmodesma.
CC Note=Assembles in tubules that are embedded within modified
CC plasmodesmata.
CC -!- SIMILARITY: Belongs to the caulimoviridae movement protein family.
CC {ECO:0000305}.
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DR EMBL; M94887; AAA46363.1; -; Genomic_DNA.
DR GO; GO:0044219; C:host cell plasmodesma; IEA:UniProtKB-SubCell.
DR GO; GO:0046740; P:transport of virus in host, cell to cell; IEA:UniProtKB-KW.
DR InterPro; IPR028919; Viral_movement.
DR Pfam; PF01107; MP; 1.
PE 3: Inferred from homology;
KW Coiled coil; Host cell junction; Host-virus interaction; Transport;
KW Viral movement protein.
FT CHAIN 1..327
FT /note="Movement protein"
FT /id="PRO_0000222063"
FT COILED 297..327
FT /evidence="ECO:0000250"
SQ SEQUENCE 327 AA; 36855 MW; CC3904510287EC08 CRC64;
MDLYPEENTQ SEQSHNSENN MQIFKSENSD GFSSDLMISN DQLKNISKTQ LTLEKEKIFK
MPNVLSQVMK KAFSRKNEIL YCVSTKELSV DIHDATGKVY LPLITKEEIN KRLSSLKPEV
RRTMSMVHLG AVKILLKAQF RNGIDTPIKI ALIDDRINSR KDCLLGAAKG NLAYGKFMFT
VYPKFGISLN TQRLNQTLSL IHDFENKNLM NKGDKVMTIT YIVGYALTNS HHSIDYQSNA
TIELEDVFQE IGNVQQSEFC TIQNDECNWA IDIAQNKALL GAKTKSQIGN SLQIGNSASS
SNTENELARV SQNIDLLKNK LKEICGE