ID   MVP_CCMV                Reviewed;         302 AA.
AC   P20180;
DT   01-FEB-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1991, sequence version 1.
DT   03-AUG-2022, entry version 74.
DE   RecName: Full=Movement protein;
DE            Short=MP;
DE   AltName: Full=Protein 3A;
GN   ORFNames=ORF3a;
OS   Cowpea chlorotic mottle virus (CCMV).
OC   Viruses; Riboviria; Orthornavirae; Kitrinoviricota; Alsuviricetes;
OC   Martellivirales; Bromoviridae; Bromovirus.
OX   NCBI_TaxID=12303;
OH   NCBI_TaxID=3847; Glycine max (Soybean) (Glycine hispida).
OH   NCBI_TaxID=3917; Vigna unguiculata (Cowpea).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=2773323; DOI=10.1016/0042-6822(89)90134-7;
RA   Allison R.F., Janda M., Ahlquist P.;
RT   "Sequence of cowpea chlorotic mottle virus RNAs 2 and 3 and evidence of a
RT   recombination event during bromovirus evolution.";
RL   Virology 172:321-330(1989).
RN   [2]
RP   FUNCTION.
RX   PubMed=10374951; DOI=10.1099/0022-1317-80-6-1357;
RA   Osman F., Schmitz I., Rao A.L.;
RT   "Effect of C-terminal deletions in the movement protein of cowpea chlorotic
RT   mottle virus on cell-to-cell and long-distance movement.";
RL   J. Gen. Virol. 80:1357-1365(1999).
CC   -!- FUNCTION: Transports viral genome to neighboring plant cells directly
CC       through plasmosdesmata, without any budding. The movement protein
CC       allows efficient cell to cell propagation, by bypassing the host cell
CC       wall barrier. Acts by forming a tubular structure at the host
CC       plasmodesmata, enlarging it enough to allow free passage of virion
CC       capsids (By similarity). {ECO:0000250, ECO:0000269|PubMed:10374951}.
CC   -!- SUBCELLULAR LOCATION: Host cell junction, host plasmodesma
CC       {ECO:0000250}. Note=Assembles into long tubular structures at the
CC       surface of the infected protoplast. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the bromovirus movement protein family.
CC       {ECO:0000305}.
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DR   EMBL; M28818; AAA46372.1; -; Genomic_RNA.
DR   PIR; JU0118; P3WMCC.
DR   RefSeq; NP_613276.1; NC_003542.1.
DR   GeneID; 962151; -.
DR   KEGG; vg:962151; -.
DR   Proteomes; UP000008445; Genome.
DR   GO; GO:0044219; C:host cell plasmodesma; IEA:UniProtKB-SubCell.
DR   GO; GO:0046740; P:transport of virus in host, cell to cell; IEA:UniProtKB-KW.
DR   InterPro; IPR000603; MPV.
DR   Pfam; PF00803; 3A; 1.
PE   3: Inferred from homology;
KW   Host cell junction; Reference proteome; Transport; Viral movement protein.
FT   CHAIN           1..302
FT                   /note="Movement protein"
FT                   /id="PRO_0000083232"
SQ   SEQUENCE   302 AA;  33363 MW;  EDD1367D029008E5 CRC64;
     MSNTTFRPFT GSSRTVVEGE QAGAQDDMSL LQSLFSDKSR EEFAKECKLG MYTNLSSNNR
     LNYIDLVPKN TGSRALNLFK SEYEKGHIPS SGVLSIPRVL VFLVRTTTVT ESGSVTIRLV
     DLISASSVEI LEPVDGTQEA TIPISSLPAI VCFSPSYDCP MQMIGNRHRC FGLVTQLDGV
     ISSGSTVVMS HAYWSANFRS KPNNYKQYAP MYKYVEPFDR LKRLSRKQLK NYVRGITNQS
     VNHGYLLGKP LLKTDEQDPE MIVLEEESLT PTDSNGVGKD KIAVTAKSVA GLPTASLSIN
     RR