ID   MVP_CERV                Reviewed;         319 AA.
AC   P05396;
DT   01-NOV-1988, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1988, sequence version 1.
DT   02-JUN-2021, entry version 64.
DE   RecName: Full=Movement protein;
DE            Short=Mov;
DE   AltName: Full=Cell-to-cell transport protein;
GN   ORFNames=ORF I;
OS   Carnation etched ring virus (CERV).
OC   Viruses; Riboviria; Pararnavirae; Artverviricota; Revtraviricetes;
OC   Ortervirales; Caulimoviridae; Caulimovirus.
OX   NCBI_TaxID=10640;
OH   NCBI_TaxID=3570; Dianthus caryophyllus (Carnation) (Clove pink).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=16453731; DOI=10.1002/j.1460-2075.1986.tb04614.x;
RA   Hull R., Sadler J., Longstaff M.;
RT   "The sequence of carnation etched ring virus DNA: comparison with
RT   cauliflower mosaic virus and retroviruses.";
RL   EMBO J. 5:3083-3090(1986).
CC   -!- FUNCTION: Transports viral genome to neighboring plant cells directly
CC       through plasmosdesmata, without any budding. The movement protein
CC       allows efficient cell to cell propagation, by bypassing the host cell
CC       wall barrier. Acts by forming tubules structures that increase the size
CC       exclusion limit (SEL) of plasmodesmata, thereby allowing viral
CC       ribonucleocapsids to spread directly to neighboring cells (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Homotrimer, through the coiled-coil domain. Interacts with
CC       VAP.
CC   -!- SUBCELLULAR LOCATION: Host cell junction, host plasmodesma
CC       {ECO:0000250}. Note=Assembles in tubules that are embedded within
CC       modified plasmodesmata.
CC   -!- SIMILARITY: Belongs to the caulimoviridae movement protein family.
CC       {ECO:0000305}.
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DR   EMBL; X04658; CAA28356.1; -; Genomic_DNA.
DR   PIR; S00850; S00850.
DR   RefSeq; NP_612573.1; NC_003498.1.
DR   GeneID; 935425; -.
DR   KEGG; vg:935425; -.
DR   Proteomes; UP000008446; Genome.
DR   GO; GO:0044219; C:host cell plasmodesma; IEA:UniProtKB-SubCell.
DR   GO; GO:0046740; P:transport of virus in host, cell to cell; IEA:UniProtKB-KW.
DR   InterPro; IPR028919; Viral_movement.
DR   Pfam; PF01107; MP; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Host cell junction; Reference proteome; Transport;
KW   Viral movement protein.
FT   CHAIN           1..319
FT                   /note="Movement protein"
FT                   /id="PRO_0000222064"
FT   REGION          1..20
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          289..319
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   319 AA;  36530 MW;  C7BBEF4ED5F43C41 CRC64;
     MNSSVEKQNS EIPEKENEEF TFQDNSQGFE LEFSTNKKTL SKIQKANLSL KTNDAFNISF
     LKAFSRKNHI YYHVNYKEFS VDICDTHGKN YLPLVTKSEI KKNLDKIKDE KVRSTISDIH
     FGAIKVLIKA RFREGINSPI KMALIDDRIT DRQDSILGAA HGNLVYGKFM FTVYPKYTTS
     ILDQRLDRTL AFIHHFERND LMRKGDKVFS ITYLVAYALA NSHHSIDYKE KDAIEIDDVF
     SEIGSVKSPT FTELDPEPNS WAIDIAQGKQ PIGFKPKPTV SNNFLRFDKE TSPSSSHQKS
     LEEISDKIDT LVVKLNNIS