ID   MVP_CFMVN               Reviewed;         108 AA.
AC   Q66011; Q0PW26;
DT   28-JUN-2011, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   07-OCT-2020, entry version 39.
DE   RecName: Full=Movement protein P1;
DE   AltName: Full=Cell-to-cell transport protein;
GN   ORFNames=ORF1;
OS   Cocksfoot mottle virus (isolate Dactylis glomerata/Norway/CfMV-NO/1995)
OS   (CfMV).
OC   Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
OC   Sobelivirales; Solemoviridae; Sobemovirus.
OX   NCBI_TaxID=1005059;
OH   NCBI_TaxID=4509; Dactylis glomerata (Orchard grass) (Cock's-foot grass).
OH   NCBI_TaxID=4565; Triticum aestivum (Wheat).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=7595389; DOI=10.1099/0022-1317-76-11-2817;
RA   Maekinen K., Tamm T., Naess V., Truve E., Puurand U., Munthe T., Saarma M.;
RT   "Characterization of cocksfoot mottle sobemovirus genomic RNA and sequence
RT   comparison with related viruses.";
RL   J. Gen. Virol. 76:2817-2825(1995).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=16732485; DOI=10.1007/s11262-005-6917-x;
RA   Meier M., Paves H., Olspert A., Tamm T., Truve E.;
RT   "P1 protein of Cocksfoot mottle virus is indispensable for the systemic
RT   spread of the virus.";
RL   Virus Genes 32:321-326(2006).
RN   [3]
RP   FUNCTION.
RX   PubMed=16971015; DOI=10.1016/j.virusres.2006.07.013;
RA   Sarmiento C., Gomez E., Meier M., Kavanagh T.A., Truve E.;
RT   "Cocksfoot mottle virus P1 suppresses RNA silencing in Nicotiana
RT   benthamiana and Nicotiana tabacum.";
RL   Virus Res. 123:95-99(2007).
CC   -!- FUNCTION: Transports viral genome to neighboring plant cells directly
CC       through plasmosdesmata, without any budding. The movement protein
CC       allows efficient cell to cell propagation, by bypassing the host cell
CC       wall barrier (Potential). Also likely to act as a suppressor of RNA-
CC       mediated gene silencing, also known as post-transcriptional gene
CC       silencing (PTGS), a mechanism of plant viral defense that performs
CC       sequence-specific inhibition of viral mRNAs expression. Silencing
CC       activity has been seen in Nicotiana benthamiana and Nicotiana tabacum,
CC       two non-host plants. {ECO:0000269|PubMed:16971015, ECO:0000305}.
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DR   EMBL; Z48630; CAA88560.1; -; Genomic_RNA.
DR   EMBL; DQ680848; ABG73617.1; -; Genomic_RNA.
DR   RefSeq; NP_941375.1; NC_002618.2.
DR   GeneID; 2654593; -.
DR   KEGG; vg:2654593; -.
DR   Proteomes; UP000001461; Genome.
DR   Proteomes; UP000008994; Genome.
DR   GO; GO:0046740; P:transport of virus in host, cell to cell; IEA:UniProtKB-KW.
PE   4: Predicted;
KW   Reference proteome; Suppressor of RNA silencing; Transport;
KW   Viral movement protein.
FT   CHAIN           1..108
FT                   /note="Movement protein P1"
FT                   /id="PRO_0000409862"
FT   CONFLICT        56
FT                   /note="S -> L (in Ref. 2; ABG73617)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        78
FT                   /note="V -> E (in Ref. 2; ABG73617)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   108 AA;  12263 MW;  775B7D537E679E27 CRC64;
     MCEPPPGFIT VQCYTSDDLL TGDSTIVKSI PVRSCFFRQG VEVVLFRCES NKHRWSKIRG
     PVSLTVHCDI CEFRETVVIP SLPKGFKVSS DFSYSVTWNC CYSRGRTE