MVP_CGMVW
ID MVP_CGMVW Reviewed; 264 AA.
AC P19522;
DT 01-FEB-1991, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1991, sequence version 1.
DT 02-JUN-2021, entry version 62.
DE RecName: Full=Movement protein;
DE AltName: Full=28.8 kDa protein;
DE AltName: Full=Cell-to-cell transport protein;
GN Name=MP;
OS Cucumber green mottle mosaic virus (strain watermelon W) (CGMMV).
OC Viruses; Riboviria; Orthornavirae; Kitrinoviricota; Alsuviricetes;
OC Martellivirales; Virgaviridae; Tobamovirus.
OX NCBI_TaxID=12237;
OH NCBI_TaxID=3653; Citrullus.
OH NCBI_TaxID=3659; Cucumis sativus (Cucumber).
OH NCBI_TaxID=3668; Lagenaria siceraria (Bottle gourd) (Lagenaria leucantha).
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX PubMed=3201760; DOI=10.1016/s0042-6822(88)90132-8;
RA Saito T., Imai Y., Meshi T., Okada Y.;
RT "Interviral homologies of the 30K proteins of tobamoviruses.";
RL Virology 167:653-656(1988).
CC -!- FUNCTION: Transports viral genome to neighboring plant cells directly
CC through plasmosdesmata, without any budding. The movement protein
CC allows efficient cell to cell propagation, by bypassing the host cell
CC wall barrier. Forms a ribonucleoprotein complex with viral RNA. Binds
CC microtubules and modulates microtubule stability. Can bind double-
CC stranded DNA. {ECO:0000250|UniProtKB:P03583,
CC ECO:0000250|UniProtKB:P69513}.
CC -!- SUBCELLULAR LOCATION: Host cytoplasm, host cytoskeleton
CC {ECO:0000250|UniProtKB:P69513}. Host cell junction, host plasmodesma
CC {ECO:0000250|UniProtKB:P69513}.
CC -!- SIMILARITY: Belongs to the tobamovirus movement protein family.
CC {ECO:0000305}.
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DR EMBL; J04322; AAA46383.1; -; Genomic_RNA.
DR PIR; JS0261; WMTMCV.
DR GO; GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0044219; C:host cell plasmodesma; IEA:UniProtKB-SubCell.
DR GO; GO:0044163; C:host cytoskeleton; IEA:UniProtKB-SubCell.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046740; P:transport of virus in host, cell to cell; IEA:UniProtKB-KW.
DR InterPro; IPR001022; TMV_movement.
DR InterPro; IPR028919; Viral_movement.
DR Pfam; PF01107; MP; 1.
DR PRINTS; PR00964; MOVEMENT.
PE 3: Inferred from homology;
KW Host cell junction; Host cytoplasm; Host cytoskeleton; RNA-binding;
KW Transport; Viral movement protein.
FT CHAIN 1..264
FT /note="Movement protein"
FT /id="PRO_0000144957"
FT REGION 221..264
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 264 AA; 28881 MW; 9412ACA560158DCC CRC64;
MSLSKVSVEN SLKPEKFVKI SWVDKLLPNY FSILKYLSIT DFSVVKAQSY ESLVPVKLLR
GVDLTKHLYV TLLGVVVSGV WNVPESCRGG ATVALVDTRM HSVAEGTICK FSAPATVREF
SVRFIPNYSV VAADALRDPW SLFVRLSNVG IKDGFHPLTL EVACLVATTN SIIKKGLRAS
VVESVVSSDQ SIVLDSLSEK VEPFFDKVPI SAAVMARDPS YRSRSQSVSG RGKRHSKPPN
RRLDSASEES SSVSFDDGLQ SDHT