ID   MVP_CLVK                Reviewed;         298 AA.
AC   P14981;
DT   01-APR-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-APR-1990, sequence version 1.
DT   03-AUG-2022, entry version 80.
DE   RecName: Full=Movement protein BC1;
DE   AltName: Full=33.7 kDa protein;
DE   AltName: Full=Movement protein BL1;
GN   ORFNames=BC1, BL1;
OS   African cassava mosaic virus (isolate West Kenyan 844) (ACMV) (Cassava
OS   latent virus (isolate West Kenyan 844)).
OC   Viruses; Monodnaviria; Shotokuvirae; Cressdnaviricota; Repensiviricetes;
OC   Geplafuvirales; Geminiviridae; Begomovirus.
OX   NCBI_TaxID=10818;
OH   NCBI_TaxID=197394; Hewittia sublobata.
OH   NCBI_TaxID=3996; Jatropha multifida (Coralbush).
OH   NCBI_TaxID=194268; Laportea.
OH   NCBI_TaxID=3983; Manihot esculenta (Cassava) (Jatropha manihot).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Stanley J., Gay M.R.;
RT   "Nucleotide sequence of cassava latent virus DNA.";
RL   Nature 301:260-262(1983).
CC   -!- FUNCTION: Transports viral genome to neighboring plant cells directly
CC       through plasmosdesmata, without any budding. The movement protein
CC       allows efficient cell to cell propagation, by bypassing the host cell
CC       wall barrier. Begomovirus genome is shuttled out of nucleus by Nuclear
CC       shuttle protein (NSP) and the movement protein transports the DNA-NSP
CC       complex to cell plasmodesmata and facilitates further movement across
CC       the cell wall (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Binds to dimeric supercoiled plasmid DNA. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Host cell membrane {ECO:0000250}; Peripheral
CC       membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Host
CC       microsome membrane {ECO:0000250}; Peripheral membrane protein
CC       {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Host endoplasmic
CC       reticulum membrane {ECO:0000250}; Peripheral membrane protein
CC       {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=Found on ER-derived
CC       vesicles. {ECO:0000250}.
CC   -!- PTM: Phosphorylated. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the begomovirus movement protein BC1 family.
CC       {ECO:0000305}.
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DR   EMBL; J02058; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   SMR; P14981; -.
DR   Proteomes; UP000008452; Genome.
DR   GO; GO:0044167; C:host cell endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0020002; C:host cell plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046740; P:transport of virus in host, cell to cell; IEA:UniProtKB-KW.
DR   InterPro; IPR000211; Gemini_BL.
DR   Pfam; PF00845; Gemini_BL1; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Host cell membrane; Host endoplasmic reticulum; Host membrane;
KW   Host microsome; Membrane; Phosphoprotein; Transport;
KW   Viral movement protein.
FT   CHAIN           1..298
FT                   /note="Movement protein BC1"
FT                   /id="PRO_0000222253"
SQ   SEQUENCE   298 AA;  33773 MW;  D1E37C3F3B4CBFA5 CRC64;
     MDTSVPVISS DYIHSARTEY KLTNDESPIT LQFPSTLERT RVRIMGKCMK VDHVVIEYRN
     QVPFNAQGSV IVTIRDTRLS DEQQDQAQFT FPIGCNVDLH YFSASYFSID DNVPWQLLYK
     VEDSNVKNGI TFAQIKAKLK LSAAKHSTDI KFKQPTIKIL SKDYGPDCVD FWSVGKPKPI
     RRLIQNEPGT DYDTGPKYRP ITVQPGETWA TKSTIGRYTS MRYTRPNPID IDDSSSKQYT
     SEAEFPLRGL HQLPEASLDP GDSISQTQSM SKKDIESIIE QTVNKCLIAH RGSSHKDL