ID   MVP_CMVQ                Reviewed;         279 AA.
AC   P03604; Q83266;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1990, sequence version 2.
DT   25-MAY-2022, entry version 76.
DE   RecName: Full=Movement protein;
DE            Short=MP;
DE   AltName: Full=Protein 3A;
GN   ORFNames=ORF3a;
OS   Cucumber mosaic virus (strain Q) (CMV).
OC   Viruses; Riboviria; Orthornavirae; Kitrinoviricota; Alsuviricetes;
OC   Martellivirales; Bromoviridae; Cucumovirus.
OX   NCBI_TaxID=12310;
OH   NCBI_TaxID=3659; Cucumis sativus (Cucumber).
OH   NCBI_TaxID=4097; Nicotiana tabacum (Common tobacco).
OH   NCBI_TaxID=4081; Solanum lycopersicum (Tomato) (Lycopersicon esculentum).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=6927855;
RA   Gould A.R., Symons R.H.;
RT   "Cucumber mosaic virus RNA 3. Determination of the nucleotide sequence
RT   provides the amino acid sequences of protein 3A and viral coat protein.";
RL   Eur. J. Biochem. 126:217-226(1982).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA], AND SEQUENCE REVISION.
RX   PubMed=3388769; DOI=10.1016/0042-6822(88)90675-7;
RA   Davies C., Symons R.H.;
RT   "Further implications for the evolutionary relationships between tripartite
RT   plant viruses based on cucumber mosaic virus RNA 3.";
RL   Virology 165:216-224(1988).
CC   -!- FUNCTION: Transports viral genome to neighboring plant cells directly
CC       through plasmosdesmata, without any budding. The movement protein
CC       allows efficient cell to cell propagation, by bypassing the host cell
CC       wall barrier. Acts by forming a tubular structure at the host
CC       plasmodesmata, enlarging it enough to allow free passage of virion
CC       capsids (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Host cell junction, host plasmodesma
CC       {ECO:0000250}. Note=Assembles into long tubular structures at the
CC       surface of the infected protoplast. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the cucumovirus movement protein family.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAA46413.1; Type=Frameshift; Evidence={ECO:0000305};
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DR   EMBL; J02059; AAA46413.1; ALT_FRAME; Genomic_RNA.
DR   EMBL; M21464; AAA46415.1; -; Genomic_RNA.
DR   PIR; JA0107; P3VXUV.
DR   Proteomes; UP000008454; Genome.
DR   GO; GO:0044219; C:host cell plasmodesma; IEA:UniProtKB-SubCell.
DR   GO; GO:0046740; P:transport of virus in host, cell to cell; IEA:UniProtKB-KW.
DR   InterPro; IPR000603; MPV.
DR   Pfam; PF00803; 3A; 1.
PE   3: Inferred from homology;
KW   Host cell junction; Reference proteome; Transport; Viral movement protein.
FT   CHAIN           1..279
FT                   /note="Movement protein"
FT                   /id="PRO_0000083247"
FT   REGION          256..279
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        261..279
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   279 AA;  30348 MW;  E1EF4E7DEA29076B CRC64;
     MAFQGPSRTL TQQSSAASSD DLQKILFSPD AIKKMATECD LGRHHWMRAD NAISVRPLVP
     QVTSNNLLPF FKSGYDAGEL RSKGYMSVPQ VLCAVTRTVS TDAEGSLKIY LADLGDKELS
     PIDGQCVTLH NHELPALISF QPTYDCPMEL VGNRHRCFAV VVERHGYIGY GGTTASVCSN
     WQAQFSSKNN NYTHAAAGKT LVLPYNRLAE HSKPSAVARL LKSQLNNVSS SRYLLPNVAL
     NQNASGHESE ILKESPPIAI GSPSASRNNS FRSQVVNGL